Skip to main content
Key Specialties
Anesthesiology Cardiology Dermatology Diabetology Endocrinology Gastroenterology and Hepatology General Medicine Geriatrics Hematology Infectious Diseases Internal Medicine Nephrology Neurology Obstetrics and Gynecology Oncology Ophthalmology Pediatrics Psychiatry Radiology Respiratory Medicine Rheumatology Surgery Urology
Congress Coverage
ASH 2024 Annual Meeting 2024 ESMO Congress 2024 ERS Congress 2024 EASD Congress 2024 ESC Congress 2024 EAN Congress 2024 ASCO Annual Meeting 2024 ACC Congress
Clinical Collections
Women’s Health Knowledge Hub Advances in Alzheimer’s

Navigating neuroimaging in Alzheimer disease care

PET imaging is playing an increasingly critical role in managing AD, but how can you effectively integrate it into clinical practice? Our expert-led program will empower you with practical strategies and real-world case studies.

This content is intended for healthcare professionals outside of the UK.
ADVANCED SEARCH
Log in
Top
Infectious Diseases and Therapy
Published in:

Open Access 09-05-2024 | Pseudomonas Aeruginosa | Original Research

Distribution of Nosocomial Pathogens and Antimicrobial Resistance among Patients with Burn Injuries in China: A Comprehensive Research Synopsis and Meta-Analysis

Authors: Yuhui Yang, Qingling Zeng, Guangyun Hu, Zhenkun Wang, Zongyue Chen, Lang Zhou, Aibo He, Wei Qian, Yu Luo, Gaoming Li

Published in: Infectious Diseases and Therapy | Issue 6/2024

Login to get access

Abstract

Introduction

Over the past decade, numerous studies have described the types of pathogens and their antibiotic resistance patterns in patients with burn injuries in China; however, the findings have generally been inconsistent. We conducted a literature search and meta-analysis to summarize the infection spectra and antimicrobial resistance patterns in patients with burn injuries.

Methods

We searched the PubMed, Embase, Web of Science, China National Knowledge Infrastructure, China Biomedical Literature, Wanfang, and Weipu databases for relevant articles published between January 2010 and December 2023. The DerSimonian–Laird random-effects model was used to estimate the proportions and 95% confidence intervals (CIs) of pathogens among Chinese patients with burn injuries. Meta-regression analyses were performed to explore differences in the proportions of pathogens among different subgroups and their resistance patterns. This study was registered with PROSPERO (CRD42024514386).

Results

The database searches yielded 2017 records; after removing duplicates and conducting initial screening, 219 articles underwent full-text screening. Ultimately, 60 studies comprising a total of 62,819 isolated strains reported the proportions of pathogens in patients with burn injuries and were included in this meta-analysis. Meta-analyses were conducted on 18 types of pathogens. The most common pathogens causing infections in Chinese patients with burn injuries were Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, and Staphylococcus epidermidis. Similar results were observed in the subgroup analysis focusing on wound infections. Since 2015, there has been a significant decrease in the proportion of Pseudomonas aeruginosa (R2 = 4.89%) and a significant increase in the proportion of Klebsiella pneumoniae (R2 = 9.60%). In terms of antibiotic resistance, there has been a significant decrease in the resistance of Staphylococcus aureus to multiple antibiotics and an increasing trend in the resistance of Klebsiella pneumoniae.

Conclusions

We systematically summarized the epidemiological characteristics and antibiotic resistance patterns of pathogens among individuals suffering from burns in China, thus providing guidance for controlling wound infections and promoting optimal empirical antimicrobial therapy. The observed high levels of antibiotic resistance underscore the need for ongoing monitoring of antibiotic usage trends.
Appendix
Available only for authorised users
Literature
1.
Price K, Lee KC, Woolley KE, et al. Burn injury prevention in low- and middle- income countries: scoping systematic review. Burns Trauma. 2021;9:tkab037.PubMedPubMedCentralCrossRef
2.
James SL, Lucchesi LR, Bisignano C, et al. Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study. Inj Prev. 2020;26(Supp 1):i36–45.PubMedCrossRef
3.
4.
Dabrowska AK, Spano F, Derler S, Adlhart C, Spencer ND, Rossi RM. The relationship between skin function, barrier properties, and body-dependent factors. Skin Res Technol. 2018;24(2):165–74.PubMedCrossRef
5.
Pruitt BA Jr, McManus AT, Kim SH, Goodwin CW. Burn wound infections: current status. World J Surg. 1998;22(2):135–45.PubMedCrossRef
6.
7.
Saaiq M, Ahmad S, Zaib MS. Burn wound infections and antibiotic susceptibility patterns at Pakistan Institute of Medical Sciences, Islamabad, Pakistan. World J Plast Surg. 2015;4(1):9–15.PubMedPubMedCentral
8.
Lachiewicz AM, Hauck CG, Weber DJ, Cairns BA, van Duin D. Bacterial infections after burn injuries: impact of multidrug resistance. Clin Infect Dis. 2017;65(12):2130–6.PubMedPubMedCentralCrossRef
9.
van Duin D, Strassle PD, DiBiase LM, et al. Timeline of health care-associated infections and pathogens after burn injuries. Am J Infect Control. 2016;44(12):1511–6.PubMedPubMedCentralCrossRef
10.
Wanis M, Walker SAN, Daneman N, et al. Impact of hospital length of stay on the distribution of Gram negative bacteria and likelihood of isolating a resistant organism in a Canadian burn center. Burns. 2016;42(1):104–11.PubMedCrossRef
11.
12.
Norbury W, Herndon DN, Tanksley J, Jeschke MG, Finnerty CC. Infection in burns. Surg Infect (Larchmt). 2016;17(2):250–5.PubMedCrossRef
13.
Zhou S, Xiao S, Wang X, Wang X, Han L. Risk factors and pathogens of wound infection in burn inpatients from East China. Antibiotics (Basel). 2023;12(9):1432.PubMedCrossRef
14.
Essayagh M, Essayagh T, Essayagh S, El Hamzaoui S. Epidemiology of burn wound infection in Rabat, Morocco: three-year review. Med Sante Trop. 2014;24(2):157–64.PubMed
15.
Organization WH. Antimicrobial resistance: global report on surveillance. World Health Organization; 2014.
16.
Pulingam T, Parumasivam T, Gazzali AM, et al. Antimicrobial resistance: prevalence, economic burden, mechanisms of resistance and strategies to overcome. Eur J Pharm Sci. 2022;170: 106103.PubMedCrossRef
17.
Gong Y, Peng Y, Luo X, et al. Different infection profiles and antimicrobial resistance patterns between burn ICU and common wards. Front Cell Infect Microbiol. 2021;11: 681731.PubMedPubMedCentralCrossRef
18.
Jin R, Yang M, Weng T, et al. Epidemiology and early bacteriology of extremely severe burns from an LPG tanker explosion in Eastern China. J Epidemiol Glob Health. 2022;12(4):478–85.PubMedPubMedCentralCrossRef
19.
20.
Hoy D, Brooks P, Woolf A, et al. Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement. J Clin Epidemiol. 2012;65(9):934–9.PubMedCrossRef
21.
Yang Y, Zhang L, Wang J, et al. Proportions of Pseudomonas aeruginosa and antimicrobial-resistant P. aeruginosa among patients with surgical site infections in China: a systematic review and meta-analysis. Open Forum Infect Dis. 2024;11(2):ofad647.PubMedCrossRef
22.
Barendregt JJ, Doi SA, Lee YY, Norman RE, Vos T. Meta-analysis of prevalence. J Epidemiol Community Health. 2013;67(11):974–8.PubMedCrossRef
23.
24.
25.
26.
Anderson-Sprecher R. Model comparisons and R2. Am Stat. 1994;48(2):113–7.
27.
Zhang J, Zhang G, Zhu C, Yang K, Song M. Analysis of distribution of pathogens and change tendency of their antimicrobial resistances in burn patients in a hospital between the year 2016 and 2020. Chin J Burns Wounds Surf Ulcers. 2023;35(4):276–82 (85).
28.
Han C, Ji P, Shang Y, et al. Epidemiological characteristics of nosocomial infection in hospitalized children with burns and the establishment and verification of a risk prediction model. Chin J Burns Wounds. 2023;39(11):1006–13.
29.
Hu J, Lu J. Analysis of distribution and drug resistance of pathogens in burn Intensive Care Unit. J Aerosp Med. 2023;34(10):1159–62.
30.
Han F, Zhang S. Changes of distribution and drug resistance of pathogenic bacteria in burn inpatients in a general hospital. Int J Lab Med. 2022;43(2):183–7 (93).
31.
Li J, Fu X, Shen K, et al. Analysis of distribution and drug resistance of pathogens in wound infection of 249 burn patients. Chin J Nosocomiol. 2022;32(24):3742–6.
32.
Liu W, Cheng X, Liang Y, Guo Y. Distribution and antimicrobial resistance of pathogens of wound infection in patients with different burn areas. Chin J Infect Control. 2022;21(1):30–6.
33.
Wang H, Zhao P, Sun D, Wu X, Yuan Q, Wang K. Epidemiological characteristics and the establishment and evaluation of a risk prediction model for nosocomial infection in burn patients. Chin J Burns Wounds. 2022;38(12):1170–8.
34.
Xu Y, Zhang G, Liu Y. Analysis of distribution and drug resistance of pathogenic bacteria in hospitalized patients with burn injuries. Chin Med J Metall Ind. 2022;39(2):217–8.
35.
Yang J, Liu M, Pan W, Liang K, Zhao Y, Yao Z. Analysis of pathogens distribution and risk factors of burn infections in burn patients. Chin J Lab Med. 2022;45(9):950–6.
36.
Yu M, Zhou X, Chen Z, et al. Distribution and drug resistance analysis of pathogenic bacteria in burned patients. Hainan Med J. 2022;33(15):1962–6.
37.
Zhu H, Qian H, Jiang J. Distribution and drug resistance of pathogenic bacteria on the wounds of burn patients in one hospital of Shaoxing. Int J Epidemiol Infect Dis. 2022;49(5):335–9.
38.
Liao W. Retrospective investigation and analysis of pathogen distribution and drug resistance in severe burn patient. Nanchang: Nanchang University; 2021.
39.
Zheng Y, Hu Q, Chi Y, et al. Analysis of wounds microbial culture in severe burn patients from 2015 to 2019. Chin J Med. 2021;56(06):616–9.
40.
Hu Y, Li D, Xu L, et al. Epidemiology and outcomes of bloodstream infections in severe burn patients: a six-year retrospective study. Antimicrob Resist Infect Control. 2021;10(1):98.PubMedPubMedCentralCrossRef
41.
Liu J, Gao W, Wang J, Han Z, Jia S, Song L. Drug resistance of pathogens of venous catheter infections in children with extensive burn. Med J Chin PAP. 2020;31(05):386–8+93.
42.
Wu P, Sun L, Zheng X. Investigation on pathogenic bacteria and drug sensitivity of burn wound infection in some hospitals in Hangzhou from 2015 to 2018. Chin J Health Lab Technol. 2020;30(24):3039–41.
43.
Chen Y-Y, Wu P-F, Chen C-S, Chen I-H, Huang W-T, Wang F-D. Trends in microbial profile of burn patients following an event of dust explosion at a tertiary medical center. BMC Infect Dis. 2020;20(1):193.PubMedPubMedCentralCrossRef
44.
Chang P, Ji R, Zhu H, et al. Analysis of bacterial distribution and drug resistance of burn patients in a hospital from 2014 to 2018. Chin Foreign Med Res. 2019;17(29):69–72.
45.
Liu Y, Huang X, Ma W, et al. Distribution and drug resistance of pathogens causing nosocomial infection in burn patients. Acad J Second Mil Univ. 2019;40(07):710–5.
46.
Ouyang A, Mao C, Che J, Xu Y, Deng F, Deng F. Analysis of the distribution and drug resistance of pathogenic bacteria that infected burn patients in 2018. Nanchang; 2019.
47.
Wu X, Liao L, Wang F, Yin J. Characteristics and drug resistance of bacterial infections in inpatients with burn surgery. Chin J Gerontol. 2019;39(7):1647–9.
48.
Xu Z, Wang S, Mi C, Han L, Wang W. Analysis of distribution and drug resistance of pathogens in burned patients. J Shanghai Jiaotong Univ. 2019;39(3):292–6.
49.
Fu Y, Yu F, Liu R, et al. Pathogenic bacteria and antimicrobial susceptibility of infected burn patients in the burn department from 2015 to 2016. J Shandong Med Coll. 2018;40(1):5–9.
50.
Yang L, Wu C, Li Q, Wang Y, Ji G, Shan B. Analysis of species distribution and drug resistance of 2073 strains of bacteria isolated from burn wounds. Chin J Antibiot. 2018;43(5):577–82.
51.
Zhang C, Gong Y, Luo X, Liu M, Peng Y. Analysis of distribution and drug resistance of pathogens from the wounds of 1310 thermal burn patients. Chin J Burns. 2018;34(11):802–8.
52.
Li L, Dai JX, Xu L, et al. Antimicrobial resistance and pathogen distribution in hospitalized burn patients: a multicenter study in Southeast China. Medicine (Baltimore). 2018;97(34): e11977.PubMedCrossRef
53.
Lin TC, Wu RX, Chiu CC, et al. The clinical and microbiological characteristics of infections in burn patients from the Formosa Fun Coast dust explosion. J Microbiol Immunol Infect. 2018;51(2):267–77.PubMedCrossRef
54.
Tang CQ, Li JQ, Shou BM, et al. Epidemiology and outcomes of bloodstream infections in 177 severe burn patients from an industrial disaster: a multicentre retrospective study. Clin Microbiol Infect. 2018;24(2):199 e1-e7.PubMedCrossRef
55.
Chen X. Analysis of the distribution trend and drug resistance of pathogens causing infections in burn patients in Shi Jiazhuang. Shijiazhuang: Hebei Medical University; 2017.
56.
Fan C, Di H, Xiang J, Tang Y. Distribution of pathogenic bacteria and analysis of drug resistance in burn inpatients of some hospital. J Logist Univ PAP. 2017;26(2):159–61.
57.
Lu K. Analysis of detection status and drug resistance changes of pathogenic bacteria caused by nosocomial infections in burn patients. World Latest Med Inf. 2017;17(91):278–9.
58.
Sun T. Comparative study on the characteristics and drug resistance of bacterial infections in inpatients with burn surgery and non-burn surgery. Contemp Med. 2017;23(3):102–3.
59.
Tan J, Hu C, Yuan L, Lei G. Study on the etiological characteristics and risk factors of nosocomial infection in burn patients. Chongqing Med. 2017;46(15):2106–8.
60.
Wang Y. Analysis of the use of antibacterial drugs and the distribution of pathogenic bacteria in patients of burns Department of People’s Hospital of Jiyuan. Chin J Burns Wounds Surf Ulcers. 2017;29(5):305–10.
61.
Xu Z, Wang S, Han L, Wang W. Analysis of distribution and drug resistance of pathogenic bacteria in burn wards. J Shanghai Jiaotong Univ. 2017;37(4):527–31.
62.
Zhang Y, Cai L, Yang Y, et al. Investigation and analysis of drug resistance of pathogens of wound infections in burned patients. Chin J Nosocomiol. 2017;27(18):4198–201.
63.
Zhang Z, Zhang L, Li C, Qi X, Jin S, Yang T. Clinical study on the distribution characteristics and prevention and treatment strategies of pathogenic bacteria in 161 patients with acute and severe burn injuries. Ningxia Med J. 2017;39(12):1155–8.
64.
Dai J, Li L, Xu L, et al. Analysis of distribution and drug resistance of pathogens isolated from 541 hospitalized children with burn infection. Chin J Burns. 2016;32(11):670–5.
65.
Li A. Analysis of drug resistance and prevention and control strategy of common pathogenic bacteria in burn ward. Qingdao: Qingdao University; 2016.
66.
Wang X, Su J, Wang Z, Fei Q, Jin X. Pathogenic bacteria distribution and drug resistance analysis of patients with large area burn. Chin J Nosocomiol. 2016;26(20):4689–91.
67.
Yan J. Analysis of pathogen distribution and drug resistance of burn patients in our hospital from 2013 to 2015. China Pharm. 2016;27(35):4930–3.
68.
Yin X, Xu X, Huang H, Shen X, Fang H. Analysis on infection pathogen and drug resistance of burned patients in dust explosion. Chin J Disinfect. 2016;33(11):1075–8.
69.
Zhang R, He Y, Pan W, Liu M. Analysis of infection etiology and drug resistance in burn patients in southern Yunnan. Med J Natl Defend Forces Southwest China. 2016;26(12):1513–6.
70.
Zhu J. Main bacteria and their drug-resistant trend that caused infection of burn patients in Wuxi during 2012–2014 and bacterial homology analysis in burn-ward’s environment. Suzhou: Soochow University; 2016.
71.
Zha B, Xu Q, Tang Y, Zhang J. Analysis of predominant pathogens of distribution and drug resistance in burn wards. Anhui Med J. 2015;36(5):536–40.
72.
Sun A, Wang W. Study on the distribution and drug resistance of pathogens in the infectious burn wound. Chin J Disinfect. 2015;32(12):1180–2.
73.
Tang W, Duan L, Chen L. Investigation and drug resistance analysis of bacterial infections in burn patients in Jingzhou City. J Yangtze Univ. 2015;12(24):39–41.
74.
Wang Y, Zheng D, Cheng D, Yan X. Distribution and drug resistance of pathogens causing burn wound infections. Chin J Nosocomiol. 2015;25(24):5663–5.
75.
Yin G, Liu Z, Dong H, Lin R, Wei J, Zhao Z. Distribution and drug resistance of pathogens in burn department of a hospital in Ningxia from 2011 to 2013. Lab Med Clin. 2015;12(04):460–2.
76.
Cen H, Wu Z, Wang F, Han C. Pathogen distribution and drug resistance in a burn ward: a three-year retrospective analysis of a single center in China. Int J Clin Exp Med. 2015;8(10):19188–99.PubMedPubMedCentral
77.
Chen C, Fan Y, Wu W, Xu X, Yang D. Distribution and drug susceptibility of pathogens causing wound infections in burn patients. Chin J Nosocomiol. 2014;24(04):841–3.
78.
Chen J, Jiang J. Analysis of bacterial resistance surveillance of infected patients in the burn department from 2010 to 2012. Int J Lab Med. 2014;35(01):111–3.
79.
Dong Y, Zhang J, Li H, Yu F. Risk factors for nosocomial infections in burn wound patients. Chin J Nosocomiol. 2014;24(09):2265–6+9.
80.
Liu H. Analyze resistant of bacteria and homology of Pseudomonas aeruginosa in Yunnan Burn Center. Kunming: Kunming Medical University; 2014. p. 35.
81.
Peng Y, He Z, Jin Q. Analysis of pathogenic bacteria and drug susceptibility results of nosocomial infections in burn patients. J Chin Med. 2014;B12:350.
82.
Wang Y, Du H, Zhou L, Yu W, Wang Y, Sui Y. Distribution and drug resistance of pathogens isolated from wound of burn patients. Chin J Nosocomiol. 2014;24(13):3185–7.
83.
Xu X, Shi C, Zhang B, Cheng S, Song J, Tang Y. Common routes of infection after burn and analysis of its pathogen distribution and drug-resistance. J Dalian Med Univ. 2014;36(5):452–5 (9).
84.
Yali G, Jing C, Chunjiang L, Cheng Z, Xiaoqiang L, Yizhi P. Comparison of pathogens and antibiotic resistance of burn patients in the burn ICU or in the common burn ward. Burns. 2014;40(3):402–7.PubMedCrossRef
85.
Alp E, Coruh A, Gunay GK, Yontar Y, Doganay M. Risk factors for nosocomial infection and mortality in burn patients: 10 years of experience at a university hospital. J Burn Care Res. 2012;33(3):379–85.PubMedCrossRef
86.
Keen EF 3rd, Robinson BJ, Hospenthal DR, et al. Incidence and bacteriology of burn infections at a military burn center. Burns. 2010;36(4):461–8.PubMedCrossRef
87.
Chaudhary NA, Munawar MD, Khan MT, et al. Epidemiology, bacteriological profile, and antibiotic sensitivity pattern of burn wounds in the burn unit of a tertiary care hospital. Cureus. 2019;11(6): e4794.PubMedPubMedCentral
88.
Ekrami A, Kalantar E. Bacterial infections in burn patients at a burn hospital in Iran. Indian J Med Res. 2007;126(6):541–4.PubMed
89.
Honnegowda TM, Kumar P, Udupa P, Rao P. Epidemiological study of burn patients hospitalised at a burns centre, Manipal. Int Wound J. 2019;16(1):79–83.PubMedCrossRef
90.
Ozkacmaz A, Dicle Y, Bayram Y, Parlak M, Akis F, Calli I. The distribution and the antimicrobial susceptibility features of microorganisms isolated from the burn wounds; a ten-year retrospective analysis. J Burn Care Res. 2024;45(2):384–97.PubMedCrossRef
91.
Foster TJ. The remarkably multifunctional fibronectin binding proteins of Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 2016;35(12):1923–31.PubMedCrossRef
92.
Foster TJ. Surface proteins of Staphylococcus aureus. Microbiol Spectr. 2019;7(4):10–1128.CrossRef
93.
Arciola CR, Campoccia D, Gamberini S, Baldassarri L, Montanaro L. Prevalence of cna, fnbA and fnbB adhesin genes among Staphylococcus aureus isolates from orthopedic infections associated to different types of implant. FEMS Microbiol Lett. 2005;246(1):81–6.PubMedCrossRef
94.
Sedaghat H, Narimani T, Nasr Esfahani B, Mobasherizadeh S, Havaei SA. Comparison of the prevalence of microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) among Staphylococcus aureus isolates in a burn unit with non-burning units. Iran J Public Health. 2021;50(1):146–51.PubMedPubMedCentral
95.
Severn MM, Horswill AR. Staphylococcus epidermidis and its dual lifestyle in skin health and infection. Nat Rev Microbiol. 2023;21(2):97–111.PubMedCrossRef
96.
Yoon J, Kym D, Hur J, et al. The clinical differentiation of blood culture-positive and -negative sepsis in burn patients: a retrospective cohort study. Burns Trauma. 2023;11:tkad031.PubMedPubMedCentralCrossRef
97.
Yang X, Liu Y, Wang L, et al. Clonal and drug resistance dynamics of methicillin-resistant Staphylococcus aureus in pediatric populations in China. Pediatr Investig. 2019;3(2):72–80.PubMedPubMedCentralCrossRef
98.
Olearo F, Albrich WC, Vernaz N, Harbarth S, Kronenberg A, Swiss Centre For Antibiotic Resistance A. Staphylococcus aureus and methicillin resistance in Switzerland: regional differences and trends from 2004 to 2014. Swiss Med Wkly. 2016;146:w14339.PubMed
99.
Amorim ML, Faria NA, Oliveira DC, et al. Changes in the clonal nature and antibiotic resistance profiles of methicillin-resistant Staphylococcus aureus isolates associated with spread of the EMRSA-15 clone in a tertiary care Portuguese hospital. J Clin Microbiol. 2007;45(9):2881–8.PubMedPubMedCentralCrossRef
100.
Otter JA, French GL. Community-associated meticillin-resistant Staphylococcus aureus strains as a cause of healthcare-associated infection. J Hosp Infect. 2011;79(3):189–93.PubMedCrossRef
101.
Organization WH. Global action plan on antimicrobial resistance. 2015.
102.
Tao Y, Wang Y, Zhang Y, et al. A qualitative study of the factors impacting implementation of the national action plan to contain antimicrobial resistance (2016–2020) in medical institutions. BMC Health Serv Res. 2024;24(1):120.PubMedPubMedCentralCrossRef
103.
104.
Gupta M, Naik AK, Singh SK. Bacteriological profile and antimicrobial resistance patterns of burn wound infections in a tertiary care hospital. Heliyon. 2019;5(12): e02956.PubMedPubMedCentralCrossRef
105.
Bayram Y, Parlak M, Aypak C, Bayram I. Three-year review of bacteriological profile and antibiogram of burn wound isolates in Van, Turkey. Int J Med Sci. 2013;10(1):19–23.PubMedCrossRef
106.
Lin XC, Li CL, Zhang SY, Yang XF, Jiang M. The global and regional prevalence of hospital-acquired carbapenem-resistant Klebsiella pneumoniae infection: a systematic review and meta-analysis. Open Forum Infect Dis. 2024;11(2):ofad649.PubMedCrossRef
107.
Darby EM, Trampari E, Siasat P, et al. Molecular mechanisms of antibiotic resistance revisited. Nat Rev Microbiol. 2023;21(5):280–95.PubMedCrossRef
108.
Shao F, Ren WJ, Meng WZ, Wang GZ, Wang TY. Burn wound bacteriological profiles, patient outcomes, and tangential excision timing: a prospective, observational study. Ostomy Wound Manag. 2018;64(9):28–36.CrossRef
109.
Luo G, Tan J, Peng Y, et al. Guideline for diagnosis, prophylaxis and treatment of invasive fungal infection post burn injury in China 2013. Burns Trauma. 2014;2(2):45–52.PubMedPubMedCentralCrossRef
110.
Babb J, Clark A, Gaffney D, Abdelfattah K, Prokesch BC. Little utility of fungal blood cultures in surgical and burn intensive care units. Microbiol Spectr. 2022;10(4): e0022822.PubMedCrossRef
111.
Köhler JR, Hube B, Puccia R, Casadevall A, Perfect JR. Fungi that infect humans. Microbiol Spectr. 2017;5(3):5.3.08.CrossRef
112.
Chayakulkeeree M, Ghannoum M, Perfect J. Zygomycosis: the re-emerging fungal infection. Eur J Clin Microbiol Infect Dis. 2006;25:215–29.PubMedCrossRef
113.
Zhou J, Tan J, Gong Y, Li N, Luo G. Candidemia in major burn patients and its possible risk factors: a 6-year period retrospective study at a burn ICU. Burns. 2019;45(5):1164–71.PubMedCrossRef
114.
Vaezi A, Fakhim H, Khodavaisy S, et al. Epidemiological and mycological characteristics of candidemia in Iran: a systematic review and meta-analysis. J Mycol Med. 2017;27(2):146–52.PubMedCrossRef
115.
Rodriguez L, Bustamante B, Huaroto L, et al. A multi-centric study of Candida bloodstream infection in Lima-Callao, Peru: species distribution, antifungal resistance and clinical outcomes. PLoS ONE. 2017;12(4): e0175172.PubMedPubMedCentralCrossRef
116.
Ronat JB, Kakol J, Khoury MN, et al. Highly drug-resistant pathogens implicated in burn-associated bacteremia in an Iraqi burn care unit. PLoS ONE. 2014;9(8): e101017.PubMedPubMedCentralCrossRef
117.
Dighriri IM, Alnomci BA, Aljahdali MM, et al. The role of clinical pharmacists in Antimicrobial Stewardship Programs (ASPs): a systematic review. Cureus. 2023;15(12): e50151.PubMedPubMedCentral
118.
Wang Y, Zhang X, Zhou Q, Xu X. Impact of selective reporting of antimicrobial susceptibility testing report on clinicians’ prescribing behavior of antibiotics. Front Pharmacol. 2023;14:1225531.PubMedPubMedCentralCrossRef
Metadata
Title
Distribution of Nosocomial Pathogens and Antimicrobial Resistance among Patients with Burn Injuries in China: A Comprehensive Research Synopsis and Meta-Analysis
Authors
Yuhui Yang
Qingling Zeng
Guangyun Hu
Zhenkun Wang
Zongyue Chen
Lang Zhou
Aibo He
Wei Qian
Yu Luo
Gaoming Li
Publication date
09-05-2024
Publisher
Springer Healthcare
Published in
Infectious Diseases and Therapy / Issue 6/2024
Print ISSN: 2193-8229
Electronic ISSN: 2193-6382
DOI
https://doi.org/10.1007/s40121-024-00983-6

Other articles of this Issue 6/2024

Implementation of AZD7442 (Tixagevimab/Cilgavimab) COVID-19 Pre-exposure Prophylaxis (PrEP) in the Largest Health Maintenance Organization in Israel: Real-world Uptake and Sociodemographic and Clinical Characteristics Across Immunocompromised Patient Groups

Nasal Staphylococcus aureus Carriage and Antimicrobial Resistance Profiles Among Community-Dwelling Adults in Jiangsu, China

  • Open Access
  • Original Research

Penetration Profiles of Four Topical Antifungals in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization–Fourier Transform Ion Cyclotron Resonance Imaging

Real-World Efficacy and Safety of Universal 8-Week Glecaprevir/Pibrentasvir for Treatment-Naïve Patients from a Nationwide HCV Registry in Taiwan

Molnupiravir Use Among Patients with COVID-19 in Real-World Settings: A Systematic Literature Review

Clinical Characteristics and Fatality Risk Factors for Patients with Listeria monocytogenes Infection: A 12-Year Hospital-Based Study in Xi’an, China

Keynote series | Spotlight on managing health in obesity

Obesity is a major contributor to cardiorenal metabolic disease, but its impact extends throughout the body. Understand how obesity can affect other organ systems and impact treatment, and whether weight-loss measures improve outcomes.

Prof. Eva L. Feldman
Prof. Jonette Keri
Developed by: Springer Medicine
Watch now
Video

Women’s health knowledge hub

Elevate your patient care with our comprehensive, evidence-based medical education on women's health. Designed to help you provide exceptional care for your female patients at every stage of life, we provide expert insights into topics such as reproductive health, menopause, breast cancer and sex-specific health risks and precision medicine.

Read more

Keynote webinar | Spotlight on advances in lupus

  • Live
  • Webinar | 27-05-2025 | 18:00 (CEST)

Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

Prof. Edward Vital
Prof. Ronald F. van Vollenhoven
Developed by: Springer Medicine
Register now
Webinar
Image Credits