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Japanese Journal of Radiology

Open Access 03-09-2024 | Prostate Cancer | Invited Review

PSMA PET/CT imaging and its application to prostate cancer treatment

Authors: Tomoaki Otani, Ryusuke Nakamoto, Shigeaki Umeoka, Yuji Nakamoto

Published in: Japanese Journal of Radiology

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Abstract

Recognition of the importance of prostate-specific membrane antigen (PSMA) PET/CT in the diagnosis of prostate cancer has steadily increased following the publication of extensive data on its diagnostic accuracy and impact on patient management over the past decade. Several recent clinical trials and investigations regarding PSMA PET/CT have been ongoing in our country, and this examination is expected to become increasingly widespread in the future. This review explains the characteristics of PSMA PET/CT, its diagnostic capabilities and superiority over other modalities, the three proposed PSMA PET/CT interpretation criteria (the European Association of Nuclear Medicine [EANM], the Prostate Cancer Molecular Imaging Standardized Evaluation [PROMISE], and the PSMA Reporting and Data System [PSMA-RADS]), and the application of PSMA PET/CT to prostate cancer treatment (improvement of local control, irradiation of oligometastases, and salvage radiotherapy), incorporating actual clinical images and the latest findings.
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Metadata
Title
PSMA PET/CT imaging and its application to prostate cancer treatment
Authors
Tomoaki Otani
Ryusuke Nakamoto
Shigeaki Umeoka
Yuji Nakamoto
Publication date
03-09-2024
Publisher
Springer Nature Singapore
Published in
Japanese Journal of Radiology
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-024-01646-9