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Current Cardiology Reports

Optimizing Sedation Strategies in the Cardiac ICU: Induction, Maintenance and Weaning

  • 01-12-2025
  • Propofol
  • Cardiovascular Critical Care (A Higgins and G Dahiya, Section Editors)
Published in:
Authors
Laith Alhuneafat
Effimia Maria Zacharia
Pratik Velangi
Jason Bartos
Alejandra Gutierrez
Published in
Current Cardiology Reports | Issue 1/2025

Abstract

Purpose of Review

We aim to summarize the available literature guiding tailored sedation practices for specific conditions encountered in the Cardiovascular Intensive Care Unit (CICU).

Recent Findings

Data specific for the CICU population is lacking. Preclinical data and observational studies guide sedation approaches for specific pathologies that we have used to generate a guideline for sedative choice for various scenarios. We discuss the challenges associated with extubation and highlight the importance of spontaneous breathing trials and role of non invasive ventilation.

Summary

Understanding the underlying pathology and the effects of sedation and positive pressure ventilation is the base to guide induction and sedation management for patients in the CICU. There is a pressing need for further research to generate high quality clinical data to improve sedation techniques in the CICU.
Title
Optimizing Sedation Strategies in the Cardiac ICU: Induction, Maintenance and Weaning
Authors
Laith Alhuneafat
Effimia Maria Zacharia
Pratik Velangi
Jason Bartos
Alejandra Gutierrez
Publication date
01-12-2025
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 1/2025
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-024-02161-z
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This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
Learn more Link opens in a new window
Image Credits
Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME