Synbiotics and Surgery: Can Prebiotics and Probiotics Affect Inflammatory Surgical Outcomes?
- 30-03-2023
- Probiotics
- REVIEW
Published in:
- Authors
- Kristin Trone
- Shahrose Rahman
- Caitlin Homberger Green
- Carla Venegas
- Robert Martindale
- Andrea Stroud
- Published in
- Current Nutrition Reports | Issue 2/2023
Abstract
Purpose of Review
Prebiotics, probiotics, and synbiotics have received increasing attention over the years for their beneficial impact on the gut microbiome and for their systemic anti-inflammatory effects. They have also been shown to improve surgical outcomes. Here, we review the inflammatory effects of surgery as well as the data which suggests a benefit of prebiotics, probiotics, and synbiotics taken in the perioperative period.
Recent Findings
Synbiotics and fermented foods may have an even greater anti-inflammatory effect than probiotics or prebiotics alone. Recent data suggest that the anti-inflammatory effects and microbiome changes brought on by prebiotics, probiotics, and synbiotics have the potential to improve surgical outcomes. We highlight the potential to alter systemic inflammation, surgical and hospital-acquired infections, colorectal cancer formation, recurrence, and anastomotic leak. Synbiotics could also impact metabolic syndrome.
Summary
Prebiotics, probiotics, and especially synbiotics may be extremely beneficial when taken in the perioperative period. Even short-term gut microbiome pre-habilitation could alter surgical outcomes significantly.
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- Title
- Synbiotics and Surgery: Can Prebiotics and Probiotics Affect Inflammatory Surgical Outcomes?
- Authors
-
Kristin Trone
Shahrose Rahman
Caitlin Homberger Green
Carla Venegas
Robert Martindale
Andrea Stroud
- Publication date
- 30-03-2023
- Publisher
- Springer US
- Keywords
-
Probiotics
Colorectal Cancer
Colorectal Cancer
Postoperative Wound Infection
Postoperative Wound Infection - Published in
-
Current Nutrition Reports / Issue 2/2023
Electronic ISSN: 2161-3311 - DOI
- https://doi.org/10.1007/s13668-023-00464-1
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