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International Urology and Nephrology
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03-01-2024 | Primary Glomerulonephritis | Nephrology - Original Paper

Demographic distribution analysis of different glomerular diseases in Southwest China from 2008 to 2022

Authors: Qianqian Han, Huan Xu, Lin Li, Song Lei, Mei Yang

Published in: International Urology and Nephrology | Issue 6/2024

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Abstract

Background

Environmental and lifestyle factors play an etiological role in the pathogenesis of different glomerular diseases. Thus, exploring the epidemic characteristics of renal disease in different nationalities and regions is important.

Materials and methods

Patients who underwent renal biopsy from October 2008 to October 2022 were included. The proportion and change tendency of glomerular diseases and the differences between the sexes and different ages and races were analyzed.

Results

There were 15,146 cases of glomerular diseases (98.5%), involving 7538 males (49.8%) and 7608 females (50.2%). The mean age was 37.0 years (range 0–80 years). The proportion of membranous nephropathy (MN) and diabetic nephropathy (DN) showed an increased trend. The most common primary glomerulonephritis (PGN) was IgA nephropathy (IgAN, 44.6%), followed by minimal-change disease (MCD, 24.3%) and MN (15.4%). Lupus nephritis (LN, 30%) accounted for the largest proportion of SGNs, followed by Henoch-Schonlein purpura nephritis (HSPN, 20.9%) and DN (19.8%). Compared with adults aged 18–60 years old, MCD and HSPN were more common in children and MN and DN in elderly individuals, statistically significant differences. Additionally, the sex and age distribution of PGN and SGN between the Tibetan and Han populations differed significantly, whereby LN was higher in the Han population and HSPN in the Tibetan population.

Conclusion

The distribution of glomerular diseases showed age, sex and race differences. This research will be beneficial for providing epidemiological evidence for clinical diagnosis, disease prevention and public health decision-making.
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Metadata
Title
Demographic distribution analysis of different glomerular diseases in Southwest China from 2008 to 2022
Authors
Qianqian Han
Huan Xu
Lin Li
Song Lei
Mei Yang
Publication date
03-01-2024
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 6/2024
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-023-03902-9

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