Skip to main content
Top
Published in:

Open Access 01-12-2024 | Research

Postoperative outcomes after splenectomy: a 20-year single-center experience in Colombia

Authors: Carlos Eduardo Rey Chaves, Sebastián Díaz, David Gómez Garnica, Oscar Cardenas, Paula Noguera, Manuela Ortíz Marín, Vanessa Velandia, Danny Conde, María Camila Rojas Gómez, María Gómez Zuleta

Published in: BMC Surgery | Issue 1/2024

Login to get access

Abstract

Background

Splenectomy indications are well documented; however, several infectious complications and potentially life-threatening conditions could arise after splenectomy. We aim to describe a 20-year single-center experience of postoperative outcomes after splenectomy and perform a subgroup analysis according to approach and surgical setting with a 30-day, 90-day, and 1-year follow-up.

Study design

A retrospective cohort study was conducted between 2003 and 2023. We included all patients aged 18 years and older who underwent splenectomy. A description of clinical and operative variables with infectious outcomes was performed. Subgroup analyses were performed between open or laparoscopic approach and surgical setting.

Results

A total of 134 patients were included. Female patients constituted 52.99% (n = 71) of cases, with a mean age of 51.01 ± 20.79 years. The most frequent surgical indication for splenectomy was trauma in 31.34% (n = 42), and a laparoscopic approach was indicated in 41.79% (n = 56). Overwhelming post-splenectomy syndrome (OPSI) was evidenced in 2.24% (n = 3) of the population. Surgical characteristics such as operative time, intraoperative blood loss, and intensive care requirement and unit length of stay were higher in open and trauma patients.

Conclusion

Our data describe the demographic, clinical and operative characteristics of patients undergoing splenectomy in Colombia, providing a solid basis for future research. The results obtained on overwhelming postsplenectomy syndrome (OPSI) and postoperative complications are comparable with those reported in the international literature, reinforcing the validity of our findings. Further prospective studies in this population are needed to optimize management strategies and improve clinical outcomes, particularly in higher risk subgroups.
Literature
1.
go back to reference Bonnet S, Guedon A, Ribeil J-A, Suarez F, Tamburini J, Gaujoux S. Indications and outcome of splenectomy in hematologic disease. J Visc Surg. 2017;154(6):421–9.CrossRefPubMed Bonnet S, Guedon A, Ribeil J-A, Suarez F, Tamburini J, Gaujoux S. Indications and outcome of splenectomy in hematologic disease. J Visc Surg. 2017;154(6):421–9.CrossRefPubMed
3.
go back to reference Lewis SM, Williams A, Eisenbarth SC. Structure-function of the immune system in the spleen. Sci Immunol. 2019;4(33):eaan6085.CrossRef Lewis SM, Williams A, Eisenbarth SC. Structure-function of the immune system in the spleen. Sci Immunol. 2019;4(33):eaan6085.CrossRef
6.
go back to reference Vercellati C, Zaninoni A, Marcello AP, Fermo E, Fattizzo B, Giannotta JA, Bianchi P, Zanella A, Barcellini W. Changing trends of splenectomy in hereditary spherocytosis: The experience of a reference Centre in the last 40 years. Br J Haematol. 2022;198(5):912–915. https://doi.org/10.1111/bjh.18106. Epub 2022 Mar 11. PMID: 35277856. Vercellati C, Zaninoni A, Marcello AP, Fermo E, Fattizzo B, Giannotta JA, Bianchi P, Zanella A, Barcellini W. Changing trends of splenectomy in hereditary spherocytosis: The experience of a reference Centre in the last 40 years. Br J Haematol. 2022;198(5):912–915. https://​doi.​org/​10.​1111/​bjh.​18106. Epub 2022 Mar 11. PMID: 35277856.
7.
go back to reference Lu Y, Li Y, Yang Y, Shi L, Ding W, Cai H, Duan Y, Chen X, Zhang Y, Nong K. Clinical effect of laparoscopic partial splenectomy for both benign tumours and trauma-10 years of experience at a single institution. ANZ J Surg. 2022;92(3):471–6. https://doi.org/10.1111/ans.17518. Epub 2022 Feb 10. PMID: 35146892.CrossRefPubMed Lu Y, Li Y, Yang Y, Shi L, Ding W, Cai H, Duan Y, Chen X, Zhang Y, Nong K. Clinical effect of laparoscopic partial splenectomy for both benign tumours and trauma-10 years of experience at a single institution. ANZ J Surg. 2022;92(3):471–6. https://​doi.​org/​10.​1111/​ans.​17518. Epub 2022 Feb 10. PMID: 35146892.CrossRefPubMed
10.
go back to reference Carr JA, Shurafa M, Velanovich V. Surgical indications in idiopathic splenomegaly. Arch Surg. 2002;137:64–8.CrossRefPubMed Carr JA, Shurafa M, Velanovich V. Surgical indications in idiopathic splenomegaly. Arch Surg. 2002;137:64–8.CrossRefPubMed
11.
go back to reference Delaitre B, Maignien B. Splenectomy by the laparoscopic approach. Report of a case. Presse Med. 1991;20:2263.PubMed Delaitre B, Maignien B. Splenectomy by the laparoscopic approach. Report of a case. Presse Med. 1991;20:2263.PubMed
12.
go back to reference Cheng J, Tao K, Yu P. Laparoscopic splenectomy is a better surgical approach for spleen-relevant disorders: a comprehensive meta-analysis based on 15-year literatures. Surg Endosc. 2016;30:1–4. Cheng J, Tao K, Yu P. Laparoscopic splenectomy is a better surgical approach for spleen-relevant disorders: a comprehensive meta-analysis based on 15-year literatures. Surg Endosc. 2016;30:1–4.
13.
go back to reference Sinwar PD. Overwhelming post-splenectomy infection syndrome—a review study. Int J Surg. 2014;12:1314–6.CrossRefPubMed Sinwar PD. Overwhelming post-splenectomy infection syndrome—a review study. Int J Surg. 2014;12:1314–6.CrossRefPubMed
14.
go back to reference Okabayashi T, Hanazaki K. Overwhelming postsplenectomy infection syndrome in adults—a clinically preventable disease. World J Gastroenterol. 2008;14:176–9.CrossRefPubMedPubMedCentral Okabayashi T, Hanazaki K. Overwhelming postsplenectomy infection syndrome in adults—a clinically preventable disease. World J Gastroenterol. 2008;14:176–9.CrossRefPubMedPubMedCentral
15.
go back to reference Newland A, Provan D, Myint S. Preventing severe infection after splenectomy. BMJ., Di Sabatino A, Lenti MV, Tinozzi FP, Lanave M, Aquino I, Klersy C, Marone P, Marena C, Pietrabissa A, Corazza GR. Vaccination coverage and mortality after splenectomy: results from an Italian single-centre study. Intern Emerg Med. 2017;12(8):1139–1147. https://doi.org/10.1007/s11739-017-1730-9. Epub 2017 Aug 10. PMID: 28799083. Newland A, Provan D, Myint S. Preventing severe infection after splenectomy. BMJ., Di Sabatino A, Lenti MV, Tinozzi FP, Lanave M, Aquino I, Klersy C, Marone P, Marena C, Pietrabissa A, Corazza GR. Vaccination coverage and mortality after splenectomy: results from an Italian single-centre study. Intern Emerg Med. 2017;12(8):1139–1147. https://​doi.​org/​10.​1007/​s11739-017-1730-9. Epub 2017 Aug 10. PMID: 28799083.
21.
go back to reference Davis JW, Chung R, Juarez DT. Prevalence of comorbid conditions with aging among patients with diabetes and cardiovascular disease. Hawaii Med J. 2011;70:209–13.PubMedPubMedCentral Davis JW, Chung R, Juarez DT. Prevalence of comorbid conditions with aging among patients with diabetes and cardiovascular disease. Hawaii Med J. 2011;70:209–13.PubMedPubMedCentral
Metadata
Title
Postoperative outcomes after splenectomy: a 20-year single-center experience in Colombia
Authors
Carlos Eduardo Rey Chaves
Sebastián Díaz
David Gómez Garnica
Oscar Cardenas
Paula Noguera
Manuela Ortíz Marín
Vanessa Velandia
Danny Conde
María Camila Rojas Gómez
María Gómez Zuleta
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2024
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-024-02637-3
SPONSORED

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

  • Webinar | 06-02-2024 | 20:00 (CET)

Severe pain is the most common symptom of chronic pancreatitis. In this webinar, experts share the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discuss pertinent cases and provide practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Healthcare
Watch now