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Digestive Diseases and Sciences

05-03-2025 | Portal Hypertension | Invited Commentary

Hot TIPS: Pre-emptive TIPS Is Effective and Should Be Used More Frequently

Authors: Anna Baiges, Joan Carles García-Pagán

Published in: Digestive Diseases and Sciences

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Excerpt

Transjugular intrahepatic portosystemic shunt (TIPS) has long been recognized as a life-changing intervention in the management of complications from portal hypertension. Initially reserved as a last resort for refractory variceal bleeding or ascites, growing evidence now supports that the pre-emptive use of TIPS (p-TIPS) in patients with variceal bleeding can significantly improve survival in selected high-risk patients [1]. Although the benefits of p-TIPS have been extensively documented, its universal application is far from realization. …
Literature
1.
García-Pagán JC, Caca K, Bureau C, et al. Early use of TIPS in patients with cirrhosis and variceal bleeding. N Engl J Med 2010; 362:2370–9CrossRefPubMed
2.
3.
Thabut D, Pauwels A, Carbonell N, et al. Cirrhotic patients with portal hypertension-related bleeding and an indication for early - TIPS: a large multicentre audit with real-life results. J Hepatol 2017; 68:73–81
4.
Nicoara-Farcau O, Han G, Rudler M, et al. Pre-emptive TIPS in high-risk acute variceal bleeding. An updated and revised individual patient meta-analysis. Hepatology 2024 1:624–635CrossRef
5.
Nicoara-Farcau O, Han G, Rudler M, et al Effects of early placement of transjugular portosystemic shunts in patients with high-risk acute variceal bleeding: a meta-analysis of individual patient data. Gastroenterology 2021;160:93–205.CrossRef
6.
Rudler M, Hernández-Gea V, Procopet B, et al. Hepatic encephalopathy is not a contraindication to pre-emptive TIPS in high-risk patients with cirrhosis with variceal bleeding.
Metadata
Title
Hot TIPS: Pre-emptive TIPS Is Effective and Should Be Used More Frequently
Authors
Anna Baiges
Joan Carles García-Pagán
Publication date
05-03-2025
Publisher
Springer US
Published in
Digestive Diseases and Sciences
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-025-08923-1

Keynote webinar | Spotlight on advances in lupus

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Systemic lupus erythematosus is a severe autoimmune disease that can cause damage to almost every system of the body. Join this session to learn more about novel biomarkers for diagnosis and monitoring and familiarise yourself with current and emerging targeted therapies.

Join us live: Tuesday 27th May, 18:00-19:15 (CEST)

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