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International Journal of Implant Dentistry
Published in:

Open Access 01-12-2017 | Short report

Porous titanium granules in the treatment of peri-implant osseous defects—a 7-year follow-up study

Authors: Heidi Andersen, Anne Merete Aass, Johan Caspar Wohlfahrt

Published in: International Journal of Implant Dentistry | Issue 1/2017

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Abstract

Background

A great number of different treatment protocols for peri-implantitis have been suggested but there is no consensus regarding the most effective intervention. The aim of the present study was to evaluate the long-term clinical and radiographic results from a study on peri-implant osseous defect reconstruction.
Patients having participated in a randomized clinical study 7 years earlier were invited for a re-examination. The treatment procedures included open flap debridement (OFD) with or without defect reconstruction with porous titanium granules (PTGs). Clinical parameters (probing pocket depth and bleeding on probing) and radiographic measurements were registered.

Findings

Of the original 32 patients, 12 patients with 12 implants were finally examined after 7 years (7.3 years [6.7–8]). Patients had been maintained one to two times yearly. The PTG group showed a mean probing pocket depth of 4.3 mm ± 2.4 compared with 3.5 mm ± 1.2 in the OFD group, at the deepest site. The change between the 12 months and the 7-year examination was similar in both groups.
Five of the test implants and five of the control implants had at least one site with positive bleeding on probing score.
The mean radiographic defect depth change as compared to 12 months was an increase of 1.9 mm ± 2.0 in the PTG group and a mean radiographic defect depth increase of 1.3 mm ± 1.4 in the OFD group.
Due to the small number of patients, a statistical analysis was not performed, but the results indicated a minimal difference in osseous defect depth as compared with baseline and between groups.
No PTG exposed to the oral cavity was observed, but the graft particles were seemingly scattered in the peri-implant soft tissue.

Conclusions

This long-term follow-up of surgical treatment of peri-implant osseous defects showed unpredictable results.
Literature
1.
Mombelli A, et al. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2(4):145–51.CrossRefPubMed
2.
Lindhe J, Meyle J. Peri-implant diseases: consensus report of the Sixth European Workshop on Periodontology. J Clin Periodontol. 2008;35(8 Suppl):282–5.CrossRefPubMed
3.
Zitzmann NU, Berglundh T. Definition and prevalence of peri-implant diseases. J Clin Periodontol. 2008;35(8 Suppl):286–91.CrossRefPubMed
4.
Klinge B, Meyle J. Peri-implant tissue destruction. The Third EAO Consensus Conference 2012. Clin Oral Implants Res. 2012;23(Suppl 6):108–10.CrossRefPubMed
5.
Esposito M, Grusovin MG, Worthington HV. Interventions for replacing missing teeth: treatment of peri-implantitis. Cochrane Database Syst Rev. 2012;1:Cd004970.PubMed
6.
Derks J, et al. Peri-implantitis—onset and pattern of progression. J Clin Periodontol. 2016;43(4):383–8.CrossRefPubMed
7.
Leonhardt A, Dahlen G, Renvert S. Five-year clinical, microbiological, and radiological outcome following treatment of peri-implantitis in man. J Periodontol. 2003;74(10):1415–22.CrossRefPubMed
8.
9.
Alffram PA, et al. Implantation of the femoral stem into a bed of titanium granules using vibration: a pilot study of a new method for prosthetic fixation in 5 patients followed for up to 15 years. Ups J Med Sci. 2007;112(2):183–9.CrossRefPubMed
10.
Turner TM, et al. Bone ingrowth through porous titanium granulate around a femoral stem: histological assessment in a six-month canine hemiarthroplasty model. Ups J Med Sci. 2007;112(2):191–7.CrossRefPubMed
11.
Bystedt H, Rasmusson L. Porous titanium granules used as osteoconductive material for sinus floor augmentation: a clinical pilot study. Clin Implant Dent Relat Res. 2009;11(2):101–5.CrossRefPubMed
12.
Wohlfahrt JC, et al. Porous titanium granules in the surgical treatment of peri-implant osseous defects: a randomized clinical trial. Int J Oral Maxillofac Implants. 2012;27(2):401–10.PubMed
13.
Hong J, et al. Titanium is a highly thrombogenic biomaterial: possible implications for osteogenesis. Thromb Haemost. 1999;82(1):58–64.PubMed
14.
Wohlfahrt JC, et al. Micro CT and human histological analysis of a peri-implant osseous defect grafted with porous titanium granules: a case report. Int J Oral Maxillofac Implants. 2011;26(1):e9–e14.PubMed
15.
Jepsen K, et al. Reconstruction of peri-implant osseous defects: a multicenter randomized trial. J Dent Res. 2016;95(1):58–66.CrossRefPubMed
16.
Serino G, Turri A. Outcome of surgical treatment of peri-implantitis: results from a 2-year prospective clinical study in humans. Clin Oral Implants Res. 2011;22(11):1214–20.CrossRefPubMed
17.
Faggion CM Jr, Listl S, Tu YK. Assessment of endpoints in studies on peri-implantitis treatment—a systematic review. J Dent. 2010;38(6):443–50.CrossRefPubMed
18.
Khoshkam V, et al. Long-term radiographic and clinical outcomes of regenerative approach for treating peri-implantitis: a systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2016;31(6):1303–10.CrossRefPubMed
19.
Schwarz F, et al. Combined surgical therapy of advanced peri-implantitis evaluating two methods of surface decontamination: a 7-year follow-up observation. J Clin Periodontol. 2017;44(3):337–42.CrossRefPubMed
20.
Roos-Jansaker AM, et al. Surgical treatment of peri-implantitis using a bone substitute with or without a resorbable membrane: a 5-year follow-up. J Clin Periodontol. 2014;41(11):1108–14.CrossRefPubMed
21.
Luterbacher S, et al. Diagnostic characteristics of clinical and microbiological tests for monitoring periodontal and peri-implant mucosal tissue conditions during supportive periodontal therapy (SPT). Clin Oral Implants Res. 2000;11(6):521–9.CrossRefPubMed
22.
Costa FO, et al. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Periodontol. 2012;39(2):173–81.CrossRefPubMed
23.
Heitz-Mayfield LJ, et al. Supportive peri-implant therapy following anti-infective surgical peri-implantitis treatment: 5-year survival and success. Clin Oral Implants Res; 2016. [Epub ahead of print]
24.
Armitage GC, Xenoudi P. Post-treatment supportive care for the natural dentition and dental implants. Periodontol. 2016;71(1):164–84.CrossRef
25.
Romeo E, et al. Therapy of peri-implantitis with resective surgery. A 3-year clinical trial on rough screw-shaped oral implants. Part II: radiographic outcome. Clin Oral Implants Res. 2007;18(2):179–87.CrossRefPubMed
26.
Sanz M, Chapple IL. Clinical research on peri-implant diseases: consensus report of Working Group 4. J Clin Periodontol. 2012;39(Suppl 12):202–6.
27.
28.
Schwarz F, et al. Impact of defect configuration on the clinical outcome following surgical regenerative therapy of peri-implantitis. J Clin Periodontol. 2010;37(5):449–55.CrossRefPubMed
29.
Roccuzzo M, et al. Surgical therapy of peri-implantitis lesions by means of a bovine-derived xenograft: comparative results of a prospective study on two different implant surfaces. J Clin Periodontol. 2011;38(8):738–45.CrossRefPubMed
Metadata
Title
Porous titanium granules in the treatment of peri-implant osseous defects—a 7-year follow-up study
Authors
Heidi Andersen
Anne Merete Aass
Johan Caspar Wohlfahrt
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Implant Dentistry / Issue 1/2017
Electronic ISSN: 2198-4034
DOI
https://doi.org/10.1186/s40729-017-0106-2

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