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Open Access 18-12-2023 | Polytrauma | Review Article

The outcomes of the most severe polytrauma patients: a systematic review of the use of high ISS cutoffs for performance measurement

Authors: Benjamin M. Hardy, Adrian Varghese, Megan J. Adams, Natalie Enninghorst, Zsolt J. Balogh

Published in: European Journal of Trauma and Emergency Surgery

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Abstract

Background

This systematic review aimed to describe the outcomes of the most severely injured polytrauma patients and identify the consistent Injury Severity Score based definition of utilised for their definition. This could provide a global standard for trauma system benchmarking.

Methods

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist was applied to this review. We searched Medline, Embase, Cochrane Reviews, CINAHL, CENTRAL from inception until July 2022. Case reports were excluded. Studies in all languages that reported the outcomes of adult and paediatric patients with an ISS 40 and above were included. Abstracts were screened by two authors and ties adjudicated by the senior author.

Results

7500 abstracts were screened after excluding 13 duplicates. 56 Full texts were reviewed and 37 were excluded. Reported ISS groups varied widely between the years 1986 and 2022. ISS groups reported ranged from 40–75 up to 51–75. Mortality varied between 27 and 100%. The numbers of patients in the highest ISS group ranged between 15 and 1451.

Conclusions

There are very few critically injured patients reported during the last 48 years. The most critically injured polytrauma patients still have at least a 50% risk of death. There is no consistent inclusion and exclusion criteria for this high-risk cohort. The current approach to reporting is not suitable for monitoring the epidemiology and outcomes of the critically injured polytrauma patients.

Level of evidence

Level 4—systematic review of level 4 studies.
Appendix
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Literature
3.
go back to reference Wong TH, Lumsdaine W, Hardy BM, Lee K, Balogh ZJ. The impact of specialist trauma service on major trauma mortality. J Trauma Acute Care Surg. 2013;74(3):780–4.CrossRefPubMed Wong TH, Lumsdaine W, Hardy BM, Lee K, Balogh ZJ. The impact of specialist trauma service on major trauma mortality. J Trauma Acute Care Surg. 2013;74(3):780–4.CrossRefPubMed
4.
go back to reference Optimal hospital resources for care of the seriously injured. Bull Am Coll Surg. 1976;61(9):15–22. Optimal hospital resources for care of the seriously injured. Bull Am Coll Surg. 1976;61(9):15–22.
5.
go back to reference Baker SP, O’Neill B, Haddon W Jr, Long WB. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14(3):187–96.CrossRefPubMed Baker SP, O’Neill B, Haddon W Jr, Long WB. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14(3):187–96.CrossRefPubMed
6.
go back to reference MacKenzie EJ, Shapiro S, Eastham JN. The Abbreviated Injury Scale and Injury Severity Score. Levels of inter- and intrarater reliability. Med Care. 1985;23(6):823–35.CrossRefPubMed MacKenzie EJ, Shapiro S, Eastham JN. The Abbreviated Injury Scale and Injury Severity Score. Levels of inter- and intrarater reliability. Med Care. 1985;23(6):823–35.CrossRefPubMed
7.
go back to reference Boyd CR, Tolson MA, Copes WS. Evaluating trauma care: the TRISS method. Trauma Score and the Injury Severity Score. J Trauma. 1987;27(4):370–8.CrossRefPubMed Boyd CR, Tolson MA, Copes WS. Evaluating trauma care: the TRISS method. Trauma Score and the Injury Severity Score. J Trauma. 1987;27(4):370–8.CrossRefPubMed
9.
go back to reference Palmer CS, Gabbe BJ, Cameron PA. Defining major trauma using the 2008 Abbreviated Injury Scale. Injury. 2016;47(1):109–15.CrossRefPubMed Palmer CS, Gabbe BJ, Cameron PA. Defining major trauma using the 2008 Abbreviated Injury Scale. Injury. 2016;47(1):109–15.CrossRefPubMed
10.
go back to reference Copes WS, Champion HR, Sacco WJ, Lawnick MM, Keast SL, Bain LW. The injury severity score revisited. J Trauma. 1988;28(1):69–77.CrossRefPubMed Copes WS, Champion HR, Sacco WJ, Lawnick MM, Keast SL, Bain LW. The injury severity score revisited. J Trauma. 1988;28(1):69–77.CrossRefPubMed
11.
go back to reference Champion HR, Copes WS, Sacco WJ, Lawnick MM, Keast SL, Bain LW Jr, et al. The Major Trauma Outcome Study: establishing national norms for trauma care. J Trauma. 1990;30(11):1356–65.CrossRefPubMed Champion HR, Copes WS, Sacco WJ, Lawnick MM, Keast SL, Bain LW Jr, et al. The Major Trauma Outcome Study: establishing national norms for trauma care. J Trauma. 1990;30(11):1356–65.CrossRefPubMed
12.
go back to reference Sampalis JS, Denis R, Lavoie A, Frechette P, Boukas S, Nikolis A, et al. Trauma care regionalization: a process-outcome evaluation. J Trauma. 1999;46(4):565–79 (discussion 79-81).CrossRefPubMed Sampalis JS, Denis R, Lavoie A, Frechette P, Boukas S, Nikolis A, et al. Trauma care regionalization: a process-outcome evaluation. J Trauma. 1999;46(4):565–79 (discussion 79-81).CrossRefPubMed
13.
go back to reference Rozenfeld M, Radomislensky I, Freedman L, Givon A, Novikov I, Peleg K. ISS groups: are we speaking the same language? Inj Prev. 2014;20(5):330–5.CrossRefPubMed Rozenfeld M, Radomislensky I, Freedman L, Givon A, Novikov I, Peleg K. ISS groups: are we speaking the same language? Inj Prev. 2014;20(5):330–5.CrossRefPubMed
15.
go back to reference TraumaRegister DGU. 20 years TraumaRegister DGU((R)): development, aims and structure. Injury. 2014;45(Suppl 3):S6–13. TraumaRegister DGU. 20 years TraumaRegister DGU((R)): development, aims and structure. Injury. 2014;45(Suppl 3):S6–13.
16.
go back to reference Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. PLoS Med. 2021;18(3): e1003583.CrossRefPubMedPubMedCentral Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. PLoS Med. 2021;18(3): e1003583.CrossRefPubMedPubMedCentral
17.
go back to reference Bagher A, Andersson L, Wingren CJ, Ottosson A, Wangefjord S, Acosta S. Outcome after red trauma alarm at an urban Swedish hospital: implications for prevention. Scand J Public Health. 2015;43(5):506–13.CrossRefPubMed Bagher A, Andersson L, Wingren CJ, Ottosson A, Wangefjord S, Acosta S. Outcome after red trauma alarm at an urban Swedish hospital: implications for prevention. Scand J Public Health. 2015;43(5):506–13.CrossRefPubMed
18.
go back to reference Ball CG, Das D, Roberts DJ, Vis C, Kirkpatrick AW, Kortbeek JB. The evolution of trauma surgery at a high-volume Canadian centre: implications for public health, prevention, clinical care, education and recruitment. Can J Surg. 2015;58(1):19–23.CrossRefPubMedPubMedCentral Ball CG, Das D, Roberts DJ, Vis C, Kirkpatrick AW, Kortbeek JB. The evolution of trauma surgery at a high-volume Canadian centre: implications for public health, prevention, clinical care, education and recruitment. Can J Surg. 2015;58(1):19–23.CrossRefPubMedPubMedCentral
19.
go back to reference Burdett-Smith P, Airey M, Franks A. Improvements in trauma survival in leeds. Injury. 1995;26(7):455–8.CrossRefPubMed Burdett-Smith P, Airey M, Franks A. Improvements in trauma survival in leeds. Injury. 1995;26(7):455–8.CrossRefPubMed
20.
go back to reference Cameron PA, Fitzgerald MC, Curtis K, McKie E, Gabbe B, Earnest A, et al. Over view of major traumatic injury in Australia-implications for trauma system design. Injury. 2020;51(1):114–21.CrossRefPubMed Cameron PA, Fitzgerald MC, Curtis K, McKie E, Gabbe B, Earnest A, et al. Over view of major traumatic injury in Australia-implications for trauma system design. Injury. 2020;51(1):114–21.CrossRefPubMed
21.
go back to reference Candefjord S, Asker L, Caragounis EC. Mortality of trauma patients treated at trauma centers compared to non-trauma centers in Sweden: a retrospective study. Eur. 2020;27:27. Candefjord S, Asker L, Caragounis EC. Mortality of trauma patients treated at trauma centers compared to non-trauma centers in Sweden: a retrospective study. Eur. 2020;27:27.
23.
go back to reference Duvall DB, Zhu X, Elliott AC, Wolf SE, Rhodes RL, Paulk ME, et al. Injury severity and comorbidities alone do not predict futility of care after geriatric trauma. J Palliat Med. 2015;18(3):246–50.CrossRefPubMedPubMedCentral Duvall DB, Zhu X, Elliott AC, Wolf SE, Rhodes RL, Paulk ME, et al. Injury severity and comorbidities alone do not predict futility of care after geriatric trauma. J Palliat Med. 2015;18(3):246–50.CrossRefPubMedPubMedCentral
24.
go back to reference Fatovich DM, Jacobs IG, Langford SA, Phillips M. The effect of age, severity, and mechanism of injury on risk of death from major trauma in Western Australia. J Trauma Acute Care Surg. 2013;74(2):647–51.CrossRefPubMed Fatovich DM, Jacobs IG, Langford SA, Phillips M. The effect of age, severity, and mechanism of injury on risk of death from major trauma in Western Australia. J Trauma Acute Care Surg. 2013;74(2):647–51.CrossRefPubMed
25.
go back to reference Jamulitrat S, Sangkerd P, Thongpiyapoom S, Na NM. A comparison of mortality predictive abilities between NISS and ISS in trauma patients. J Med Assoc Thai. 2001;84(10):1416–21.PubMed Jamulitrat S, Sangkerd P, Thongpiyapoom S, Na NM. A comparison of mortality predictive abilities between NISS and ISS in trauma patients. J Med Assoc Thai. 2001;84(10):1416–21.PubMed
26.
go back to reference Kaweski SM, Sise MJ, Virgilio RW. The effect of prehospital fluids on survival in trauma patients. J Trauma. 1990;30(10):1215–9.CrossRefPubMed Kaweski SM, Sise MJ, Virgilio RW. The effect of prehospital fluids on survival in trauma patients. J Trauma. 1990;30(10):1215–9.CrossRefPubMed
27.
go back to reference Kuhne CA, Ruchholtz S, Kaiser GM, Nast-Kolb D. Mortality in severely injured elderly trauma patients–when does age become a risk factor? World J Surg. 2005;29(11):1476–82.CrossRefPubMed Kuhne CA, Ruchholtz S, Kaiser GM, Nast-Kolb D. Mortality in severely injured elderly trauma patients–when does age become a risk factor? World J Surg. 2005;29(11):1476–82.CrossRefPubMed
28.
go back to reference Mann SM, Banaszek D, Lajkosz K, Brogly SB, Stanojev SM, Evans C, et al. High-energy trauma patients with pelvic fractures: management trends in Ontario, Canada. Injury. 2018;49(10):1830–40.CrossRefPubMed Mann SM, Banaszek D, Lajkosz K, Brogly SB, Stanojev SM, Evans C, et al. High-energy trauma patients with pelvic fractures: management trends in Ontario, Canada. Injury. 2018;49(10):1830–40.CrossRefPubMed
29.
go back to reference Russell R, Halcomb E, Caldwell E, Sugrue M. Differences in mortality predictions between Injury Severity Score triplets: a significant flaw. J Trauma. 2004;56(6):1321–4.CrossRefPubMed Russell R, Halcomb E, Caldwell E, Sugrue M. Differences in mortality predictions between Injury Severity Score triplets: a significant flaw. J Trauma. 2004;56(6):1321–4.CrossRefPubMed
30.
go back to reference Sampalis JS, Boukas S, Nikolis A, Lavoie A. Preventable death classification: interrater reliability and comparison with ISS-based survival probability estimates. Accid Anal Prev. 1995;27(2):199–206.CrossRefPubMed Sampalis JS, Boukas S, Nikolis A, Lavoie A. Preventable death classification: interrater reliability and comparison with ISS-based survival probability estimates. Accid Anal Prev. 1995;27(2):199–206.CrossRefPubMed
31.
go back to reference van der Sluis CK, Klasen HJ, Eisma WH, ten Duis HJ. Major trauma in young and old: what is the difference? J Trauma. 1996;40(1):78–82.CrossRefPubMed van der Sluis CK, Klasen HJ, Eisma WH, ten Duis HJ. Major trauma in young and old: what is the difference? J Trauma. 1996;40(1):78–82.CrossRefPubMed
32.
go back to reference Vyhnanek F, Fric M, Pazout J, Waldauf P, Ocadlik M, Dzupa V. Present concept for management of severely injured patients in Trauma Centre Faculty Hospital Kralovske Vinohrady. Cas Lek Cesk. 2012;151(10):468–71.PubMed Vyhnanek F, Fric M, Pazout J, Waldauf P, Ocadlik M, Dzupa V. Present concept for management of severely injured patients in Trauma Centre Faculty Hospital Kralovske Vinohrady. Cas Lek Cesk. 2012;151(10):468–71.PubMed
33.
go back to reference Wurm S, Rose M, von Ruden C, Woltmann A, Buhren V. Severe polytrauma with an ISS ≥ 50. Z Orthop Unfall. 2012;150(3):296–301.CrossRefPubMed Wurm S, Rose M, von Ruden C, Woltmann A, Buhren V. Severe polytrauma with an ISS ≥ 50. Z Orthop Unfall. 2012;150(3):296–301.CrossRefPubMed
Metadata
Title
The outcomes of the most severe polytrauma patients: a systematic review of the use of high ISS cutoffs for performance measurement
Authors
Benjamin M. Hardy
Adrian Varghese
Megan J. Adams
Natalie Enninghorst
Zsolt J. Balogh
Publication date
18-12-2023
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Trauma and Emergency Surgery
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-023-02409-3