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Polycystic ovary syndrome (PCOS) is a major health issue for females, resulting in a substantial health and economic burden globally [1]. Its manifestations often occur throughout the lifespan, typically arising in childhood and evolving through adolescence into adulthood [2], affecting approximately 6.3% of adolescent girls [3]. The aetiology of PCOS is complex, with a heterogenous clinical presentation involving reproductive, metabolic, and psychological features [4]. Women worldwide often experience delayed diagnosis and dissatisfaction with care [4], issues that are even more pronounced during adolescence [5], impacting the assessment and management of affected girls (Fig. 1).
Fig. 1
Diagnosis of polycystic ovary syndrome (PCOS) in adolescence [2]. aExclusion of other causes requires testing thyroid-stimulating hormone, prolactin, 17-OH progesterone, and follicle-stimulating hormone. If clinical assessment is suggestive, then other causes need to be excluded (e.g., Cushing’s syndrome, adrenal tumors, etc.)
Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?