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Polycystic Ovary Syndrome

Inositols and female reproductive disorders

Consensus statement from the women’s endocrinology working group of the SIE on the use of inositols across four key domains: menses irregularity and anovulation, fertility, pregnancy outcomes, and neonatal outcomes.

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Editor's Choice

Oral micronized progesterone for diagnosis and therapy

Micronized progesterone can be used for the diagnosis and therapy of various endocrine conditions, from amenorrhea to premenstrual syndrome, PCOS, perimenopause, and menopause.

Impact of PCOS on quality of life

Polycystic ovary syndrome is the most common endocrinopathy in women of reproductive age, but what impact do symptoms, including psychological symptoms and cognitive alterations, have on quality of life?

The H-P-O axis and adiposity-related alterations in PCOS

This review addresses the main adiposity-related alterations in polycystic ovary syndrome, focusing on the hypothalamic-pituitary-ovarian axis, and provides an overview of therapeutic strategies.

PCOS: A risk factor for CVD

A review on the pathophysiological pathways that confer cardiovascular risk in individuals with polycystic ovary syndrome, with discussion of effective interventions to reduce CVD risk.

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Current Reviews

The prevalence and risk of anxiety and depression in polycystic ovary syndrome: an overview of systematic reviews with meta-analysis

Polycystic ovary syndrome (PCOS) may be defined as a combination of signs and symptoms characterized by the presence of androgen excess and ovarian dysfunction once other diagnoses (e.g., hyperprolactinemia) are ruled out.(Azziz et al. 2009 ; …

What do we know about abnormally low prolactin levels in polycystic ovary syndrome? A narrative review

Hyper and hypoprolactinemia seem to be related to the occurrence of metabolic alterations in PCOS patients. In contrast, between significantly elevated and significantly low, prolactin levels seem to be protective against metabolic consequences.

Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

Polycystic Ovary Syndrome (PCOS) is a multifactorial endocrine disorder characterized by a spectrum of symptoms including ovulatory dysfunction, hyperandrogenism, and metabolic abnormalities, with insulin resistance being one of the key …

Effects of Intermittent Fasting on Female Reproductive Function: A Review of Animal and Human Studies

Intermittent fasting, a dietary approach characterized by alternating cycles of eating and fasting, has garnered considerable research attention and public interest in recent years [ 1 – 10 ]. In contrast to traditional continuous …

Further Reading

What do we know about abnormally low prolactin levels in polycystic ovary syndrome? A narrative review

Hyper and hypoprolactinemia seem to be related to the occurrence of metabolic alterations in PCOS patients. In contrast, between significantly elevated and significantly low, prolactin levels seem to be protective against metabolic consequences.

Identification of necroptosis-related gene expression and the immune response in polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a complex female reproductive dysfunction and metabolic disorder, and the main clinical manifestations are infertility, anovulation, or thin ovulation caused by menstrual disorders, hyperandrogenemia, and …

The prevalence of abnormal semen parameters in male partners of women with anovulatory polycystic ovarian syndrome: a retrospective case–control study

Polycystic ovarian syndrome (PCOS) is an endocrinologic and metabolic disorder in women of reproductive age with global prevalence estimates ranging from 6 to 10% [ 1 ]. The syndrome is commonly accompanied by irregularities in the menstrual cycle …

The effect of vitamin D supplementation on markers of insulin resistance in women with polycystic ovarian syndrome: a systematic review

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age, affecting approximately one fifth of women of reproductive age [ 1 ] and it is the leading cause of anovulatory infertility in women [ 2 ].