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Child's Nervous System
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10-01-2022 | Pineal Tumor | Case Report

Pineal anlage tumor: a case report and review of the literature

Authors: Eduardo Cambruzzi, Mateus Scarabelot Medeiros, Jose Nathan Andrade Muller da Silva, Gabriella Bezerra Cortês Nascimento, Natália Brandelli Zandoná, Willian Pegoraro Kus

Published in: Child's Nervous System | Issue 8/2022

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Abstract

Purpose

Pineal anlage tumors (PAT) are extremely rare malignant tumors in the pediatric population considered to be a variant of pineoblastomas. These tumors are characterized by a combination of neuroectodermal and heterologous ectomesenchymal components. PAT can be clinically aggressive and has a propensity to cerebrospinal fluid (CSF) dissemination. So far, only 13 cases of these tumors have been reported in the literature.

Case Article

In this article, we report the case of an anlage tumor in a 3-year-old girl with a rapidly aggressive course.
Literature
1.
Favero G, Bonomini F, Rezzani R (2021) Pineal gland tumors: a review. Cancers 13(7):1547PubMed
2.
Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger et al (2021) Neuro Oncol 23(8):1231–1251CrossRef
3.
Mc Grogan G, Rivel J, Vital C, Guerin JA (1992) Pineal tumor with features of pineal anlage tumor. Acta Neurochir 117:73–77CrossRef
4.
Ahuja A, Sharma MC, Suri V, Sarkar C, Sharma BS, Garg A (2011) Pineal anlage tumor – a rare entity with divergent histology. J Clin Neurosci 18:811–813CrossRef
5.
Uppal DK, Madan R, Chatterjee D et al (2021) Pineal anlage tumor: a case report and infant-pathological review. Clin Neurol Neurosurg 206:106629
6.
Schmidbauer M, Budka H, Pilz P (1989) Neuroepithelial and ectomesenchymal differentiation in a primitive pineal tumor (pineal anlage tumor). Clin Neuropathol 8:7–10PubMed
7.
Raisanen J, Vogel H, Horoupian DS (1990) Primitive pineal tumor with retinoblastomatous and retinal/ciliary epithelial differentiation: an immunohistochemical study. J Neurooncol 9:165–170CrossRef
8.
Gudinaviciene I, Pranys D, Zheng P, Kros JMA (2005) 10-month-old boy with a large pineal tumor. Brain Pathol 15:263–264CrossRef
9.
Berns S, Pearl G (2006) Review of pineal anlage tumor with divergent histology. Arch Pathol Lab Med 130:1233–1235CrossRef
10.
Olaya JE, Raghavan R, Totaro L, Zouros A (2010) Pineal anlage tumor in a 5-month-old boy. J Meurosurg Pediatrics 5:636–640CrossRef
11.
Rodríguez-Velasco A, Ramírez-Reyes AG (2014) Tumor pineal anlage en un niño de 8 meses. Primer caso informado en lengua hispana Rev Med Inst Mex Seguro Soc 52(Suppl 2):S90–S93
12.
Ajayi O, Palma A, Sadanand V, Deisch J (2014) Pineal anlage tumor: case report and review of literature. JSM Neurosurg Spine 2(4):1035
13.
Ramdasi R, Kothari K, Goel N, Mahore A (2015) An unusual variant of anlage tumor of pineal region in an infant. Brain Tumor Res Treat 3:52–55CrossRef
14.
Homma T, Hemmi A, Ohta T, Kusumi Y, Yoshino A, Hao H (2017) A rare case of a pineoblastoma with a rhabdomyoblastic component. Neuropathology 37:227–232CrossRef
15.
Li JY, Chen L (2020) Pineal anlage tumor: report of a case. Chin J Pathol 49(11):1190–1192
Metadata
Title
Pineal anlage tumor: a case report and review of the literature
Authors
Eduardo Cambruzzi
Mateus Scarabelot Medeiros
Jose Nathan Andrade Muller da Silva
Gabriella Bezerra Cortês Nascimento
Natália Brandelli Zandoná
Willian Pegoraro Kus
Publication date
10-01-2022
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 8/2022
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-021-05441-z

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