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14-07-2021 | Phlebothrombosis | Original Article

Postoperative venous thromboembolism event increases risk of readmissions and reoperation following total joint arthroplasty: a propensity-matched cohort study

Authors: Vivek Singh, Nishanth Muthusamy, Chibuokem P. Ikwuazom, Chelsea Sue Sicat, Ran Schwarzkopf, Joshua C. Rozell

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 6/2022

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Abstract

Purpose

The clinical impact of postoperative venous thromboembolism (VTE) following total joint arthroplasty (TJA) remains unclear. In this study, we evaluate the effect of VTE following TJA on postoperative outcomes including discharge disposition, readmission rates, and revision rates.

Methods

We retrospectively reviewed all patients over the age of 18 who underwent primary, elective THA or TKA between 2013 and 2020. Patients were stratified into two cohorts based on whether or not they had a VTE following their procedure. Baseline patient demographics and clinical outcomes such as readmissions and revisions were collected. Propensity score matching was performed to limit significant demographic differences, while independent sample t-tests and Pearson’s chi-squared test were used to compare outcomes of interest between the groups.

Results

After propensity score matching, there were 109 patients in each cohort, representing a total of 218 patients for the matched comparison. Prior to matching, the VTE cohort was noted to have a significantly higher BMI than the non-VTE cohort (32.22 ± 6.27 vs 30.93 ± 32.04 kg/m2, p = 0.032). All other patient demographics were similar. Compared to the non-VTE cohort, the VTE cohort was less likely to be discharged home (66.1% vs 80.7%; p = 0.021), had a higher rate of 90-day all-cause readmissions (27.5% vs 9.2%, p = 0.001), and a higher two-year revision rate (11.0% vs 0.9%, p = 0.003).

Conclusion

Patients with postoperative VTE were less likely to be discharged home and had higher 90-day readmission and two-year revision rates. Therefore, mitigating perioperative risk factors, initiating appropriate long-term anticoagulation, and maintaining close follow-up for patients with postoperative VTE may play significant roles in decreasing hospital costs and the economic burden to the healthcare system.

Level of evidence III

Retrospective Cohort Study.
Literature
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Metadata
Title
Postoperative venous thromboembolism event increases risk of readmissions and reoperation following total joint arthroplasty: a propensity-matched cohort study
Authors
Vivek Singh
Nishanth Muthusamy
Chibuokem P. Ikwuazom
Chelsea Sue Sicat
Ran Schwarzkopf
Joshua C. Rozell
Publication date
14-07-2021
Publisher
Springer Paris
Published in
European Journal of Orthopaedic Surgery & Traumatology / Issue 6/2022
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-021-03071-4