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04-05-2024 | Peridural Anesthesia | Original Article

Prospective observational study comparing the perioperative outcomes of laparoscopic colectomy with or without epidural anesthesia: the Kanagawa Yokohama Colorectal Cancer Study Group (KYCC) 1806

Authors: Aya Kato, Masakatsu Numata, Shota Izukawa, Takashi Ohgimi, Hironao Okamoto, Yosuke Atsumi, Keisuke Kazama, Masahiro Asari, Koji Numata, Sho Sawazaki, Takuo Watanabe, Yo Mikayama, Teni Godai, Akio Higuchi, Hiroyuki Saeki, Shinsuke Hatori, Hiroyuki Mushiake, Satomi Matsumoto, Yasushi Rino, Aya Saito, Manabu Shiozawa

Published in: Surgery Today

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Abstract

Purpose

There have been no adequate comparisons of the efficacy, safety, and efficiency of analgesia after laparoscopic colorectal resection (LAC), with and without epidural anesthesia (EDA).

Methods

This was a multicenter prospective observational study of patients undergoing LAC. The primary end point was the mean visual analog scale (VAS) score on postoperative days (PODs) 1–7. The secondary end points were the highest VAS, complication rate, days to first ambulation and fatigue, length of hospital stay, and time to commencement of surgery.

Results

We compared an EDA group (Group E, n = 48) and a no-EDA group (Group O, n = 48) after matching. The mean VAS was not significantly different between the groups (28.7 vs. 30.1, p = 0.288). On assessing the secondary end points, the highest VAS was not significantly different between the groups. In fact, the VAS was lower in Group E only on POD 2. There was no difference in the incidence of complications, the time to first postoperative evacuation was shorter in Group E, and postoperative hospitalization was similar. The time to surgery was shorter in Group O.

Conclusion

These results suggest that LAC without EDA is a feasible option, but with the early and regular use of adjunctive measures to provide more stable analgesia.
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Metadata
Title
Prospective observational study comparing the perioperative outcomes of laparoscopic colectomy with or without epidural anesthesia: the Kanagawa Yokohama Colorectal Cancer Study Group (KYCC) 1806
Authors
Aya Kato
Masakatsu Numata
Shota Izukawa
Takashi Ohgimi
Hironao Okamoto
Yosuke Atsumi
Keisuke Kazama
Masahiro Asari
Koji Numata
Sho Sawazaki
Takuo Watanabe
Yo Mikayama
Teni Godai
Akio Higuchi
Hiroyuki Saeki
Shinsuke Hatori
Hiroyuki Mushiake
Satomi Matsumoto
Yasushi Rino
Aya Saito
Manabu Shiozawa
Publication date
04-05-2024
Publisher
Springer Nature Singapore
Published in
Surgery Today
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-024-02856-4
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