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Current Cardiology Reports

Autoimmune Pericarditis: Diagnosis and New Therapeutics

  • Open Access
  • 15-07-2025
  • Pericardial Disease
  • Pericardial Disease (AL Klein and CL Jellis, Section Editors)
Published in:
Authors
Heba Wassif
Elizabeth Ghandakly
Habib Layoun
Jaideep Singh Bhalla
Emily Littlejohn
Tom Kai Ming Wang
Elaine Husni
Allan Klein
Published in
Current Cardiology Reports | Issue 1/2025

Abstract

Purpose of Review

To provide an overview of the diagnosis and updated therapeutic approach to autoimmune pericarditis.

Recent Findings

Subtypes of autoimmune pericarditis may benefit from IL-1 inhibition and future phenotyping based on clinical presentation, biomarkers, and imaging may aid in guiding future therapeutic approaches.

Summary

Autoimmune pericarditis is a unique phenotype of pericarditis for which there is scarce data. The clinical spectrum of pericardial involvement associated with autoimmune disorders varies in acuity, recurrence, severity, and symptomatic presentation. There is a pathophysiologic distinction that separates autoimmune and autoinflammatory pericarditis from other pericarditis presentations. This review explores the state of the art in diagnosis and therapeutic management.
Title
Autoimmune Pericarditis: Diagnosis and New Therapeutics
Authors
Heba Wassif
Elizabeth Ghandakly
Habib Layoun
Jaideep Singh Bhalla
Emily Littlejohn
Tom Kai Ming Wang
Elaine Husni
Allan Klein
Publication date
15-07-2025
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 1/2025
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-025-02248-1
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This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
Learn more Link opens in a new window
Image Credits
Anatomical heart made of felt textile in red background/© Carol Yepes/ Getty, Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME