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Child's Nervous System

24-08-2024 | Pediatric Neurology | Mini Review

Pott’s puffy tumor with intracranial extension in a child with incontinentia pigmenti: case based review of the eponymous disease

Authors: Debajyoti Datta, Albert Tu

Published in: Child's Nervous System

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Abstract

Background

Pott’s puffy tumor (PPT) is an uncommon infection involving the frontal bone, first described by Sir Percival Pott more than 250 years ago. It can present with intracranial extension and serious neurological morbidity. Incontinentia pigmenti (IP) is a rare inherited genodermatosis that is lethal prenatally in males and manifests clinically in females. IP is associated with recurrent infections and immune dysfunction/suppression.

Methods

We report a case of Pott’s puffy tumor presenting in a child with IP. We also performed a literature review of reported cases of PPT associated with immune dysfunction. We discuss the clinical presentation, diagnosis, and management of these lesions.

Results

We identified 12 cases of PPT associated with immune dysfunction/suppression. Diabetes was the most commonly identified cause followed by iatrogenic immunosuppression. Surgery is the standard treatment for managing PPT and the management of PPT with and without intracranial involvement, particularly in the context of underlying immune dysfunction/suppression, is discussed.

Conclusion

PPT remains a rare but not infrequent diagnosis, often requiring neurosurgical intervention. Immune dysfunction/suppression is an additional risk factor that may predispose to PPT. Early and aggressive management should be instituted for optimal outcome.
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Metadata
Title
Pott’s puffy tumor with intracranial extension in a child with incontinentia pigmenti: case based review of the eponymous disease
Authors
Debajyoti Datta
Albert Tu
Publication date
24-08-2024

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