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Published in: Journal of Clinical Psychology in Medical Settings 4/2023

21-01-2023

Pediatric Hematopoietic Cell Transplantation: A Longitudinal Assessment of Health-Related Quality of Life of Pediatric Donors

Authors: Sharon H. J. Hou, Mehak Stokoe, Hailey Zwicker, Morgan Young-Speirs, Wendy Pelletier, Gregory M. T. Guilcher, Melanie Khu, Fiona S. M. Schulte

Published in: Journal of Clinical Psychology in Medical Settings | Issue 4/2023

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Abstract

Pediatric donors may be at increased risk of psychological and social challenges following hematopoietic cell transplantation (HCT). Through a retrospective chart review, we evaluated the health-related quality of life (HRQL) of pediatric donors over time and examined facilitators and barriers to implementing a longitudinal psychosocial assessment. Fifty-one pediatric donors (M = 10.7 years, SD = 3.7) completed an HRQL questionnaire across six time points (T1 to T6) from prior to donation to 2 years after. Change in mean scores was assessed using a linear mixed-effect model for repeated measures design. Facilitators and barriers to implementation were examined. HRQL of pediatric donors improved between T1 and T6 with significant change in physical, emotional, and overall functioning. Facilitators to retention included the support of a clinical coordinator. Barriers to implementation included the absence of infrastructure to maintain contact with pediatric and their families. HRQL of pediatric donors of HCT improved steadily over time. Pattern of results suggests a need to further explore factors that contribute to change across time. Development of a longitudinal standardized assessment protocol that can be prospectively and feasibly implemented is integral to supporting the well-being of this group.
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Metadata
Title
Pediatric Hematopoietic Cell Transplantation: A Longitudinal Assessment of Health-Related Quality of Life of Pediatric Donors
Authors
Sharon H. J. Hou
Mehak Stokoe
Hailey Zwicker
Morgan Young-Speirs
Wendy Pelletier
Gregory M. T. Guilcher
Melanie Khu
Fiona S. M. Schulte
Publication date
21-01-2023
Publisher
Springer US
Published in
Journal of Clinical Psychology in Medical Settings / Issue 4/2023
Print ISSN: 1068-9583
Electronic ISSN: 1573-3572
DOI
https://doi.org/10.1007/s10880-022-09933-1

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