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Open Access 23-07-2024 | Pediatric Cardiology | Case Report

Regression of cardiac angiosarcoma in a 17-year-old: a percutaneous biopsy effect

Authors: Noor Sharrack, Martine Parent, Christopher Lethaby, Ulrich Rosendahl, MD, Alexander R Lyon, Maryum Farooq, Haqeel Jamil, John P. Greenwood, Sven Plein, Ananth Kidambi

Published in: Cardio-Oncology | Issue 1/2024

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Abstract

Background

Cardiac angiosarcoma is a very rare and aggressive primary cardiac tumor associated with poor prognosis. Diagnosis is often delayed due to non-specific symptoms, with most cases involving metastases at the time of diagnosis. We describe a unique case of apparent tumor regression of cardiac angiosarcoma post percutaneous biopsy.

Case Presentation

A young male was admitted with suspected pericarditis. Echocardiogram revealed a pericardial mass. Cardiovascular magnetic resonance (CMR) suggested primary cardiac malignancy. Percutaneous biopsy was inconclusive, with subsequent CMR demonstrating apparent tumor regression. Interval imaging revealed further tumor growth, and surgical biopsy revealed primary cardiac angiosarcoma (PCAS). Causes of tumor regression following percutaneous biopsy are discussed.

Conclusions

Cases of suspected primary cardiac malignancy require careful follow up with serial multimodality imaging. Percutaneous biopsy effects should be considered in cases of tumor regression, and serial imaging should be planned afterwards.
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Metadata
Title
Regression of cardiac angiosarcoma in a 17-year-old: a percutaneous biopsy effect
Authors
Noor Sharrack
Martine Parent
Christopher Lethaby
Ulrich Rosendahl, MD
Alexander R Lyon
Maryum Farooq
Haqeel Jamil
John P. Greenwood
Sven Plein
Ananth Kidambi
Publication date
23-07-2024
Publisher
BioMed Central
Published in
Cardio-Oncology / Issue 1/2024
Electronic ISSN: 2057-3804
DOI
https://doi.org/10.1186/s40959-024-00239-9

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