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Ophthalmology

Who’s eligible for intraocular lens implantation?

Inconsistent terminology and statistical inaccuracies have perpetuated confusion about eye axes in intraocular lens selection, leading to unnecessary exclusion of patients. What does the latest evidence say?

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Editor's Choice

Ocular adverse event of COVID-19 vaccination

A rare case of acute zonal occult outer retinopathy complex, inciting from torpedo retinopathy and starting 3 days after the patient’s second recombinant mRNA vaccine.

No rebound effect after myopic teens discontinue multifocal lenses

There is no loss of treatment effect after older children with myopia discontinue using high-add center-distance soft multifocal contact lenses.

JAK inhibition promising for refractory Behçet’s disease

A patient with Behçet's disease refractory to standard therapies, and complicated by uveitis and axial spondyloarthritis, responded to treatment with upadacitinib, pointing to a role for JAK inhibition in this setting.

How to treat neurotrophic keratitis

NK involves reduced or absent corneal sensation, which can impair vision and threaten viability of the eye. Management is challenging, but novel therapies are emerging from improved understanding of corneal nerves.

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Case Studies

Ocular adverse event of COVID-19 vaccination

A rare case of acute zonal occult outer retinopathy complex, inciting from torpedo retinopathy and starting 3 days after the patient’s second recombinant mRNA vaccine.

JAK inhibition promising for refractory Behçet’s disease

A patient with Behçet's disease refractory to standard therapies, and complicated by uveitis and axial spondyloarthritis, responded to treatment with upadacitinib, pointing to a role for JAK inhibition in this setting.

Retinal vascular complications of oral contraceptives

The first case of simultaneous central retinal vein occlusion and cilioretinal artery occlusion in a young female patient associated with short-term use of progestin-only oral contraceptives.

Current Reviews

To Treat or Not to Treat? Resolving the Question of Subretinal and Intraretinal Fluid in Age-Related Macular Degeneration: A Narrative Review

Neovascular age-related macular degeneration (nAMD) is associated with considerable quality of life and economic burden. nAMD is characterized by pathological neovascularization, leading to the accumulation of retinal fluid. Intraretinal fluid …

Cataract surgery risk stratification models: a systematic review

By systematically categorizing cataract surgery patients pre-operatively into distinct groups based on their likelihood of complications, risk stratification models can assist cataract surgeons in clinical decision-making [ 1 – 4 ]. These models …

Pediatric Society of the African League Against Rheumatism juvenile idiopathic arthritis recommendations for enthesitis-related arthritis and juvenile psoriatic arthritis

The objective of this study is to develop evidence-based recommendations for the diagnosis and management of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) in the African context. The recommendations for ERA and JPsA …

Further Reading

Dose-finding and efficacy confirmation trial of the superselective intra-arterial infusion of cisplatin and concomitant radiation therapy for locally advanced maxillary sinus cancer (JCOG1212): final analysis

Maxillary sinus squamous cell carcinoma (MS-SCC) is often detected at an advanced stage because of the lack of symptoms in early-stage cases [ 1 , 2 ]. Surgery for locally advanced maxillary sinus squamous cell carcinoma (LA-MS-SCC) leads to …

Relationships between tilt angles of rectus muscles and positions of rectus muscle pulleys in patients with sagging eye syndrome

Binocular misalignment causes approximately two-thirds of new-onset diplopia cases in adults aged > 40 years in California [ 1 ] and one-third in older patients in Japan [ 2 ]. The two most common causes of adult diplopia are sagging eye syndrome …

To Treat or Not to Treat? Resolving the Question of Subretinal and Intraretinal Fluid in Age-Related Macular Degeneration: A Narrative Review

Neovascular age-related macular degeneration (nAMD) is associated with considerable quality of life and economic burden. nAMD is characterized by pathological neovascularization, leading to the accumulation of retinal fluid. Intraretinal fluid …

AZD6738 Attenuates LPS-Induced Corneal Inflammation and Fibrosis by Modulating Macrophage Function and Polarization

This study aimed to evaluate the therapeutic potential of AZD6738, an ATR inhibitor, in LPS-induced bacterial keratitis (BK) by targeting macrophage function and polarization. A murine model of LPS-induced BK was established, with AZD6738 (100 µM) …