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High lifetime alcohol intake tied to elevated risk for CRC

Analysis of data from the PLCO cancer screening trial has revealed a significant association between higher lifetime drinking and an increased risk for colorectal cancer.

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Editor's Choice

Localized bile duct stricture mimicking cholangiocarcinoma

A case of eosinophilic cholangitis presenting as a localized biliary stricture in a 65-year-old man. As perihilar cholangiocarcinoma could not be ruled out, the patient opted for surgical intervention.

Bacterial contributions to oncogenesis

From the mechanistic contributions of pathogenic bacteria to tumor initiation, to the role dysbiosis plays in influencing systemic cancer behavior, understand the impact bacteria has as a driver of cancer development.

Long-term PPI use may not increase stomach cancer risk

A large population-based study has found no significant association between long-term use of proton pump inhibitors and an increased risk for gastric adenocarcinoma.

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Keynote webinar | Spotlight on progress in colorectal cancer

CRC remains a major global health burden, but advances in screening, treatment, and lifestyle-based prevention continue to reshape clinical practice. Gain insights into how the latest research can be leveraged to optimize patient care across the CRC continuum.

Prof. Antoni Castells
Prof. Harpreet Wasan
Prof. Edward Giovannucci
Watch now

Are you up to date on targeted therapies for relapsed/refractory AML? 

Join Prof. Amer Zeidan and his expert guests to hear about innovations in molecular testing, emerging therapies, and IDH-targeted treatments, and get practical advice for improving your patient care.

Supported by: independent educational grant from Rigel

Find out more
SPONSORED

Masterclass webinar: Expert review of CAR T-cell therapy patient cases in R/R DLBCL or R/R FL

Join Professor Joy Ho as she leads a panel of Asia-Pacific-based experts, discussing real-life patient cases and their experiences with CAR T-cell therapy for the treatment of R/R DLBCL or R/R FL. Learn about how to identify appropriate patients for CAR T-cell therapy and how to optimize outcomes with this treatment modality. Gain insights into essential aspects of pre- and post-infusion management, as well as important considerations for treatment sequencing.

This educational activity is not intended for healthcare professionals based in the UK, US, or off-label Asia-Pacific countries.

Sponsored by:
  • Novartis Pharma AG
Prof. Joy Ho
Prof. William Hwang
Dr. Kentaro Fukushima
Prof. Dok Hyun Yoon
Prof. Miki Ando
Developed by: Springer Health+
Learn more
Video

Case Studies

Localized bile duct stricture mimicking cholangiocarcinoma

A case of eosinophilic cholangitis presenting as a localized biliary stricture in a 65-year-old man. As perihilar cholangiocarcinoma could not be ruled out, the patient opted for surgical intervention.

Monozygotic twins with discordant thyroid cancers

Familial thyroid cancers are well documented, but in this rare report one monozygotic twin sister had metastatic poorly differentiated thyroid carcinoma and the other recurrent papillary thyroid carcinoma.

Episode 25: Therapeutic cancer vaccines

The next frontier in cancer treatment?

Recently there has been a renewed interest in the prospect of therapeutic cancer vaccines. But what exactly does it mean to vaccinate against cancer, where are vaccines showing the most promise, and what are the challenges of making such vaccines a reality?

Dr. Elias Sayour answers these questions and more in this episode.

Dr. Elias Sayour
Listen now
Podcast

Current Reviews

Updated evaluation of additional surgery versus non-gastrectomy treatment for early gastric cancer after noncurative endoscopic resection: a meta-analysis

In general, supplemental surgery with lymph node dissection is primarily suggested for patients who have undergone noncurative resection because of the likelihood of local and further LNM [ 5 , 6 ]. However, some patients firmly refuse additional …

CT presentations of hepatic lymphoma: what radiologists need to know

Hepatic lymphomas are rare malignancies that are classified as either primary hepatic lymphoma (PHL) or secondary hepatic lymphoma (SHL). They can present with several CT patterns, including a solid focal lesion, multifocal lesions, a diffuse …

Emerging advances in non-surgical ablation for early-stage breast cancer

Recent advances in diagnostic imaging have led to an increase in the detection of early-stage breast cancer, prompting growing interest in minimally invasive breast surgery. These approaches include the omission of axillary lymph node dissection …

Aplastic anemia: managing special patient subgroups and challenging cases (Link opens in a new window)

Learn more about the importance of adapting treatment approaches for special patient populations (eg, elderly or pregnant patients) in this third module of our interactive e-Learning program on diagnosing and treating aplastic anemia.

Supported by:
  • Pfizer
Developed by: Springer Health+ IME
Learn more

CME & eLearning

SPONSORED

Masterclass webinar: Expert review of CAR T-cell therapy patient cases in R/R DLBCL or R/R FL

Professor Joy Ho and a panel of Asia-Pacific-based experts will examine real-life patient cases in this Masterclass, exchanging insights into their clinical experiences of using CAR T-cell therapy to treat patients with R/R DLBCL or R/R FL.

This educational activity is not intended for healthcare professionals based in the UK, US, or off-label Asia-Pacific countries.

Sponsored by:
  • Novartis Pharma AG
SPONSORED

CAR T-cell therapy medical education hub

This hub presents a curated selection of educational materials focused on the latest clinically relevant topics related to the use of chimeric antigen receptor (CAR) T‑cell therapy for the treatment of relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and R/R follicular lymphoma (FL).

This content has been developed in collaboration with and funded by the sponsor Novartis Pharma AG and is not intended for healthcare professionals based in the UK and US.

Sponsored by:
  • Novartis Pharma AG

The AML expert series

Hear directly from experts in acute myeloid leukemia about innovations in molecular testing, emerging therapies, and targeted treatments, and get practical advice for improving the care of your patients with relapsed or refractory disease.

Supported by:
  • Rigel Pharmaceuticals, Inc.
Developed by: Springer Health+ IME

Further Reading

Updated evaluation of additional surgery versus non-gastrectomy treatment for early gastric cancer after noncurative endoscopic resection: a meta-analysis

In general, supplemental surgery with lymph node dissection is primarily suggested for patients who have undergone noncurative resection because of the likelihood of local and further LNM [ 5 , 6 ]. However, some patients firmly refuse additional …

Selective cytotoxicity of solamargine via oxidative stress and caspase-independent mechanisms in human glioblastoma cells

IDH-wild-type glioblastoma (IDH-wildtype GB) is an aggressive and genetically heterogeneous tumor characterized by intrinsic resistance to radiotherapy and chemotherapy, while surgical resection remains inherently limited by its diffuse …

AI software as a third reader in breast cancer screening—a prospective diagnostic observational study

Breast cancer remains a leading cause of cancer-related morbidity and mortality in women [ 1 , 2 ]. Mammography screening has reduced breast cancer mortality in many countries [ 3 , 4 ]. Nevertheless, not all cancers are detected by screening: data …

Related topics

Portal hypertension following inotuzumab treatment

Long-term monitoring for portal hypertension is important – even after resolution of acute sinusoidal obstruction syndrome and achievement of leukemia remission – to optimize outcomes in inotuzumab ozogamicin-treated patients.

Read more

High lifetime alcohol intake tied to elevated risk for CRC

Analysis of data from the PLCO cancer screening trial has revealed a significant association between higher lifetime drinking and an increased risk for colorectal cancer.

Read more
Image Credits
Assortment of glasses of wine and beer/© MarkWagonerProductions / Getty Images / iStock, Intraoperative photo of carotid endarterectomy/© 2026, Mingyang Qiu et al, J Med Case Reports, Peroral cholangioscopy at a hepatic hilar bile duct stricture/© 2026, Takeshi Mori et al, Clin J Gastroenterol, under exclusive licence to Japanese Society of Gastroenterology, Malignant cancer cells/© koto_feja / Getty Images / iStock, Transparent pink and clear capsules/© mitand73 / stock.adobe.com, Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images, Patient taking a color blindness test/© rudi_suardi / Getty Images / iStock, Man standing in a supermarket aisle and reading the label on a grocery item/© Giselleflissak / Getty Images / iStock (symbolic image with model), Older man sitting on the edge of a bed/© andreswd / E+ / Getty Images (symbolic image with model), Mammogram image on a screen/© Valerii Apetroaiei / stock.adobe.com, CAR T-cell attacking cancer cells/© LoveLive/stock.adobe.com, Poorly differentiated thyroid carcinoma with local invasion and distant metastases/© 2026, Amal El Masri et al, Thyroid Res, Medicine Matters Podcast promo image/© Springer Medizin GmbH, Aplastic Anemia/© Springer Healthcare IME, T-cell expressing chimeric antigen receptor (CAR) in the cell membrane; DNA is exposed from the T-cell to highlight the genetic engineering involved in creating CAR T-cells/© LoveLive/stock.adobe.com, Leukemia background in bright colors, including white and red blood cells in realistic style/© Double Brain/Shutterstock.com, IV drip/© Trsakaoe / stock.adobe.com, FDG PET-CT of patient with Behçet disease and Hodgkin lymphoma/© 2025, Matthew Coulter et al, under exclusive licence to International League of Associations for Rheumatology (ILAR), Clin Rheumatol, Fundus scan in vitreoretinal lymphoma/© 2025, Atsunobu Takeda et al, Jpn J Ophthalmol, Antibody drug conjugates/© huenstructurebio.com / stock.adobe.com, Close-up of subcutaneous injection syringe/© Laures / Getty Images / iStock, Doctor showing patient information on tablet/© Alina555 / Getty Images / iStock (symbolic image with models)