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Unusual metastasis of olfactory neuroblastoma

A young man previously diagnosed with olfactory neuroblastoma started experiencing thigh pain and was found to have a bone metastasis. Early identification of skeletal involvement and prompt orthopedic intervention is crucial.

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Editor's Choice

Non-islet cell tumor hypoglycemia and sarcoma

NICTH was diagnosed in a man with pelvic sarcoma. Severe hypoglycemia did not respond to standard treatments but had a partial response to rhGH and angioembolization of the tumor.

Radiation-induced lung injury

What are the underlying mechanisms that cause radiation-induced lung injury, the most common adverse effect of thoracic radiotherapy? What is the prognosis and how can it be treated?

Statins protect against HCC and hepatic decompensation in CLD

People with chronic liver disease who take statins have a reduced risk for hepatocellular carcinoma and hepatic decompensation, especially when they are taken for a longer duration.

Sugary drinks tied to increased oral cancer risk

High consumption of sugar-sweetened beverages may be associated with a significantly increased risk for oral cavity cancer in women.

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At a glance: The DESTINY-Breast trials

The antibody–drug conjugate trastuzumab deruxtecan is being investigated in the DESTINY-Breast trials for the treatment of breast cancer.

Developed by: Springer Medicine
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SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
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Video

Case Studies

Unusual metastasis of olfactory neuroblastoma

A young man previously diagnosed with olfactory neuroblastoma started experiencing thigh pain and was found to have a bone metastasis. Early identification of skeletal involvement and prompt orthopedic intervention is crucial.

Non-islet cell tumor hypoglycemia and sarcoma

NICTH was diagnosed in a man with pelvic sarcoma. Severe hypoglycemia did not respond to standard treatments but had a partial response to rhGH and angioembolization of the tumor.

Pheochromocytoma with heterotaxy syndrome

A unique finding of pheochromocytoma in a young adult with heterotaxy syndrome and a functioning ectopic spleen. The patient remained stable on alpha-blockers having decided not to undergo surgery.

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

Current Reviews

Chinese management guidelines for radioactive iodine-refractory differentiated thyroid cancer (2025 edition)

Up to two-thirds of patients with locally advanced and metastatic differentiated thyroid cancer (DTC) eventually develop radioactive iodine (RAI)-refractory or resistant DTC (RAIR-DTC), which usually progress rapidly with poor prognosis.

Advances in classification and treatment of primary cutaneous lymphomas

Primary cutaneous lymphomas (PCLs) are a heterogeneous group of extranodal non-Hodgkin lymphomas, characterized with skin involvement as the primary or predominant manifestation. While early-stage PCLs typically have a favorable prognosis …

Biomarkers in prostate cancer: current status and future directions in radiotherapy—statement from the Prostate Cancer Working Group of the German Society of Radiation Oncology (DEGRO)

Prostate cancer (PCa) is the most frequently diagnosed malignancy of men in Germany. Advances in diagnostics and treatment, with improved cure rates in localized and metastatic stages, have transformed PCa into a chronic disease. Risk …

Fear of cancer recurrence interventions for breast cancer survivors in the 2020s: a systematic review

Breast cancer survivors (BCSs) face various psychosocial challenges, including anxiety, sadness, fear of cancer recurrence (FCR), and a decreased quality of life, due to treatment or the illness itself [ 1 ]. Among them, FCR is one of the largest …

Episode 15: Breastfeeding after breast cancer

POSITIVEly reassuring results from a clinical trial

The POSITIVE trial previously showed that women with breast cancer can safely interrupt endocrine therapy in order to become pregnant. But what about breastfeeding - is that possible and safe for the mother and baby?

Women can take heart from the latest findings, says Dr. Cristina Saura, as she takes us through these important clinical updates.

Dr. Cristina Saura
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Podcast

CME & eLearning

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME

Further Reading

Chinese management guidelines for radioactive iodine-refractory differentiated thyroid cancer (2025 edition)

Up to two-thirds of patients with locally advanced and metastatic differentiated thyroid cancer (DTC) eventually develop radioactive iodine (RAI)-refractory or resistant DTC (RAIR-DTC), which usually progress rapidly with poor prognosis.

Systemic inflammatory response markers improve the discrimination for prognostic model in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the seventh most common cancer and the second leading cause of cancer-related deaths worldwide. The overlap between incidence and mortality (830,000 deaths per year) reflects the dismal prognosis of this disease …

A US Survey Across Seven Early-Stage Cancers Assessing the Humanistic Burden of Recurrence on Patients and Caregivers

More than two million people were estimated to be diagnosed with a new cancer in the USA in 2024 [ 1 ]. Patients diagnosed with early-stage cancers are at substantial risk of developing recurrences. Results from a systematic review (May 2012–May …

Advances in classification and treatment of primary cutaneous lymphomas

Primary cutaneous lymphomas (PCLs) are a heterogeneous group of extranodal non-Hodgkin lymphomas, characterized with skin involvement as the primary or predominant manifestation. While early-stage PCLs typically have a favorable prognosis …

Related topics

What is causing meningoencephalitis?

After unsuccessful antibiotic treatment of an immunocompromised patient with mantle cell lymphoma and 2 months of meningoencephalitis in the brainstem and spine, biopsy and CSF culture identified Candida albicans infection.

Read more

Unusual metastasis of olfactory neuroblastoma

A young man previously diagnosed with olfactory neuroblastoma started experiencing thigh pain and was found to have a bone metastasis. Early identification of skeletal involvement and prompt orthopedic intervention is crucial.

Read more