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The evolving treatment landscape of advanced prostate cancer

The advent of PSMA-targeted radioligand therapies and bispecific T-cell engagers has provided new hope for patients with metastatic castration-resistant prostate cancer. Explore the latest evidence.

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Editor's Choice

Reassuring results for ART use in BRCA breast cancer survivors

The use of assisted reproductive technology to conceive after breast cancer in young BRCA1/2 carriers does not appear to worsen disease-free survival or pregnancy outcomes.

A-RT promising for high-risk patients with pancreatic cancer

Ablative radiation therapy can be an alternative option to surgery for the treatment of localized, resectable pancreatic ductal adenocarcinoma, particularly in cases of high surgical risk.

YKL-40 linked to GI cancer risk in type 2 diabetes

Raised YKL-40 levels are associated with an increased risk for obesity-related and gastrointestinal cancers, particularly liver cancer, in people with type 2 diabetes.

Gastric cancer guidelines: exploring international differences

What can we learn from the similarities and differences between gastric cancer guidelines of different countries, and how might this understanding be used to improve patient care?

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Women’s health knowledge hub

Elevate your patient care with our comprehensive, evidence-based medical education on women's health. Designed to help you provide exceptional care for your female patients at every stage of life, we provide expert insights into topics such as reproductive health, menopause, breast cancer and sex-specific health risks and precision medicine.

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Incorporating comprehensive genomic profiling into the standard-of-care for NSCLC and thyroid cancer

In this interactive webinar, experts Dr. Subbiah, Dr. Drilon, and Dr. Williams discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations.

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Dr. Vivek Subbiah
Dr. Alexander Drilon
Dr. Michelle Williams
Developed by: Springer Healthcare
Watch now
Video

Case Studies

Long-term outcomes after giant cavernous sinus hemangioma

Cavernous sinus hemangiomas are rare vascular tumors characterized by significant intraoperative bleeding which makes management extremely difficult. This case reports the 15 year follow up, without neurological compromise, after successful ligation of the left internal carotid artery during resection. 

Prolactinoma management: a complex path

This case highlights the challenges associated with managing an aggressive macroprolactinoma that's resistant to conventional treatments and explores the use of immunotherapy.

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

At a glance: The DESTINY-Breast trials

The antibody–drug conjugate trastuzumab deruxtecan is being investigated in the DESTINY-Breast trials for the treatment of breast cancer.

Developed by: Springer Medicine
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Current Reviews

Current and future pharmacological therapies for extensive-stage small-cell lung cancer

  • Open Access
  • SCLC
  • short review

Small-cell lung cancer represents a highly aggressive neuroendocrine subtype of lung cancer. In distant metastatic or extensive-stage small-cell lung cancer, the primary treatment approach consists of non-curative pharmacological therapy.

Natural products that target p53 for cancer therapy

Wild-type p53 acts as a tumor suppressor, but p53 is frequently mutated and inactivated in tumor cells, promoting cancer progression, invasion, and metastasis. Thus, compounds that reactivate p53 may be leveraged for cancer treatment, and the …

Rare Genetic and Uncommon Morphological Entities in Adults with Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clonal disorder of immature hematopoietic cells and is characterized by aberrant hematopoietic cellular proliferation and maturation. Over last decades, major advances have been made in the understanding of AML …

The Improving Outcomes in Relapsed-Refractory Diffuse Large B Cell Lymphoma: The Role of CAR T-Cell Therapy

Diffuse large B cell lymphoma, not otherwise specified (DLBCL-NOS) is the most common aggressive lymphoma and can be cured with CHOP-R immunochemotherapy in 60% of cases. The second-line therapy includes salvage regimens followed by autologous …

Elevate your expertise in aplastic anemia (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME
Learn more

CME & eLearning

Webinar

In this interactive webinar, experts discuss best pathological practices within NSCLC and thyroid cancer, as well as how genomic testing can improve outcomes in clinical practice, using patient case studies as illustrations. 

This content is intended only for US-based healthcare providers.

Supported by:
  • Illumina, Inc., and Eli Lilly and Company
Developed by: Springer Healthcare

eLearning (Link opens in a new window)

Transform the way you care for your patients with aplastic anemia with our 3-module series using real-world case studies and expert insights. Discover why early diagnosis matters, explore the benefits and risks of current treatments, and develop tailored approaches for complex cases. 

Supported by:
  • Pfizer
Developed by: Springer Healthcare IME

eLearning | Interviews | Digital Treatment Map | Patient Cases (Link opens in a new window)

0.75 AMA PRA Category 1 Credit(s)

Expert-led, multiformat program which will address the individualized management of NSCLC, through education on the detection of NTRK gene fusions, current evidence-based guidelines, and new and emerging therapies. Will also include guidance on integrating shared decision making into your clinical practice, drawing on insights from a patient on how best to communicate.

Supported by:
  • Bayer HealthCare Pharmaceuticals Inc.
Developed by: Springer Healthcare IME

Further Reading

Minichromosome maintenance 4 is associated with poor survival and stemness of patients with pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the most well-known cancer types, with a persistently poor 5-year survival rate. We previously reported MCM4 as a molecule associated with cancer stem cells; however, its role in PDAC has not been …

Neuroendocrine Carcinoma Presenting as Metastasis of Unknown Origin in Cervical Lymph Nodes: An Unwonted Case Report

Neuroendocrine carcinomas occurring in cervical lymph nodes are few and far between. Such presentations demand meticulous clinic-radiological workup besides appropriate immunohistochemical evaluation. We present an adequately managed case of …

A multicenter randomized open-label phase 2 study investigating optimal antiemetic therapy for patients with advanced/recurrent gastric cancer treated with trastuzumab deruxtecan: the EN-hance study

Gastric cancer (GC) is one of the most common cancers worldwide, causing more than 700,000 deaths annually [ 1 ]. Systemic chemotherapy is the standard treatment for patients with advanced unresectable GC [ 2 , 3 ]. Despite improvements in …

Combination of pre-transplant flow cytometry, WT1 expression, and NGS for MRD monitoring is potent in predicting the prognosis of AML receiving allogeneic transplantation

Minimal residual disease (MRD) monitoring has been demonstrated to important in predicting prognosis in acute myeloid leukemia (AML) receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT), but the ideal time point and method …

Related topics

Skin infection or lymphoma in a woman with type 2 diabetes?

Cutaneous lymphoma should be considered in patients with long-standing, poorly controlled type 2 diabetes and chronic non-healing skin lesions. In this case, primary cutaneous B-cell lymphoma was misdiagnosed as a skin infection.

Read more

The evolving treatment landscape of advanced prostate cancer

The advent of PSMA-targeted radioligand therapies and bispecific T-cell engagers has provided new hope for patients with metastatic castration-resistant prostate cancer. Explore the latest evidence.

Read more