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Tumor microenvironment and management of medullary thyroid cancer

The absence or presence of primary tumor desmoplasia may be an alternative to conventional classification systems to help guide intraoperative management of sporadic medullary thyroid cancer.

Read more

Editor's Choice

EBV screening may reduce NPC mortality

A Chinese trial suggests that screening for serum Epstein-Barr virus antibodies could reduce mortality from nasopharyngeal carcinoma.

Combination therapy for HCC

Delve into the current evidence and ongoing clinical trials for combinations of immunotherapeutic and targeted agents for the treatment of hepatocellular carcinoma.

Pulmonary toxicities of NSCLC systemic therapy

  • Open Access
  • NSCLC
  • Review

Drug-induced pneumonitis is a common side effect of lung cancer systemic therapy. This review provides a detailed management approach for pneumonitis caused by chemotherapy, antibody–drug conjugates, targeted therapy, or immunotherapy.

Exceptionally rare manifestation of papillary thyroid cancer

Spontaneous hepatic hemorrhage is a rare condition that is mostly seen in patients with hepatocellular carcinoma or hepatic adenomas. But in this case it was caused by metastasized papillary thyroid cancer.

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2024 ESMO Congress

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

  • Webinar | 01-10-2024 | 12:30 (CEST)

Live event concluded

In this webinar, Professor Martin Dreyling and an esteemed, international panel of CAR-T experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by: Novartis Pharma AG

Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
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Case Studies

Exceptionally rare manifestation of papillary thyroid cancer

Spontaneous hepatic hemorrhage is a rare condition that is mostly seen in patients with hepatocellular carcinoma or hepatic adenomas. But in this case it was caused by metastasized papillary thyroid cancer.

Worsening heart failure in a survivor of cancer as a young adult

Severe cardiomyopathy presenting 20 years after anthracycline treatment for non-Hodgkin’s lymphoma during early adulthood. The patient's worsening heart failure was successfully managed with multidrug treatment with add-on vericiguat and ivabradine based on quadruple therapy. 

Unusual presentation of ALL

A child with acute lymphoblastic leukemia presented with nephrogenic diabetes insipidus as the initial symptom. ALL should be considered in the differential diagnosis of unexplained renal injury, even if blood investigations are normal.

At a glance: The KEYNOTE lung cancer trials

A quick guide to the KEYNOTE trials investigating the anti-PD-1 agent pembrolizumab in non-small-cell and small-cell lung cancer.

Developed by: Springer Medicine
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Current Reviews

Updates in Systemic Treatment of Hormone Receptor-Positive Early-Stage Breast Cancer

Hormone-receptor positive (HR +) and human epidermal growth factor receptor 2 (HER2) negative early breast cancer (eBC) is a heterogeneous disease with several contributing factors for increased risk of recurrence, including tumor features …

Traditional Chinese Medicine Herbs for Breast Cancer Prevention and Survival: A Narrative Review of Epidemiological Studies from Taiwan

Breast cancer is the most commonly diagnosed malignancy in women worldwide, accounting for 24.5% of all cancer cases globally [ 1 ]. In 2020 alone, 2.3 million women were diagnosed with breast cancer. Patients in western countries are increasingly …

Molecular Testing in Gliomas: What is Necessary in Routine Clinical Practice?

Diffuse gliomas are the most common malignant primary brain tumors in adults [ 1 ]. Diffuse gliomas are thought to arise from glial precursor (progenitor) cells. They include astrocytoma, oligodendroglioma and ependymoma, among a few other rare …

Uterine-Conserving Treatment Options for Atypical Endometrial Hyperplasia and Early Endometrial Cancer

Endometrial cancer (EC) is the only gynecologic malignancy with a rising incidence rate in the United States with 67,880 new cases and 13,250 deaths estimated in the U.S. in 2024 [ 1 ]. The median age at diagnosis of EC is 63 years, and because 67% …

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
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CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME

eLearning (Link opens in a new window)

The evolving landscape of metastatic urothelial carcinoma brings with it many challenges, such as optimally sequencing therapies and managing adverse events. Navigate your way through these with the Ultimate mUC challenge game and expert-to-expert interviews.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany and Astellas
Developed by: Springer Healthcare IME

Further Reading

Molecular Testing in Gliomas: What is Necessary in Routine Clinical Practice?

Diffuse gliomas are the most common malignant primary brain tumors in adults [ 1 ]. Diffuse gliomas are thought to arise from glial precursor (progenitor) cells. They include astrocytoma, oligodendroglioma and ependymoma, among a few other rare …

Diagnostic performance of TILs–US score and LPBC in biopsy specimens for predicting pathological complete response in patients with breast cancer

Tumor-infiltrating lymphocytes (TILs) are lymphocytes that penetrate tumor tissues and serve as prognostic and predictive factors in various types of cancer [ 1 – 3 ]. Breast cancer with high TILs is referred to as lymphocyte–predominant breast …

Interval breast cancer rates for tomosynthesis vs mammography population screening: a systematic review and meta-analysis of prospective studies

Digital mammography (DM) is currently the standard imaging method for breast cancer (BC) screening in most settings. Over the past decade, digital breast tomosynthesis (DBT) has been increasingly considered as a replacement for DM. By reducing …

Prolactin deficiency in the context of other pituitary hormone abnormalities

Prolactin deficiency is rare. It generally occurs when pituitary disorders, such as large pituitary tumors, pituitary apoplexy, and other conditions associated with sellar mass effect lead to global failure of pituitary function and …

Related topics

Worsening heart failure in a survivor of cancer as a young adult

Severe cardiomyopathy presenting 20 years after anthracycline treatment for non-Hodgkin’s lymphoma during early adulthood. The patient's worsening heart failure was successfully managed with multidrug treatment with add-on vericiguat and ivabradine based on quadruple therapy. 

Read more

Tumor microenvironment and management of medullary thyroid cancer

The absence or presence of primary tumor desmoplasia may be an alternative to conventional classification systems to help guide intraoperative management of sporadic medullary thyroid cancer.

Read more