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Cardiometabolic risks in cancer survivorship

Managing cardiometabolic health in patients with a history of cancer is increasingly important. Discover the primary considerations including impact of demographic variables, cancer types, and treatment modalities. 

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Editor's Choice

Advances in treating pLGG

Free for a limited time Glioma in Children Review

Pediatric low-grade gliomas often cause long-term morbidities despite high overall survival rates. But advances in molecular characterization, targeted therapies, and surgical techniques are improving management and outcomes.

Concurrent pulmonary cryptococcosis and lung cancer

Open Access Cryptococcosis Case Study

This case serves as a prompt to consider the possibility of cryptococcosis, even when lung cancer has already been diagnosed, when lung radiology shows multiple nodules.

Uncommon type of malignant melanoma

Open Access Melanoma Case Study

The amelanotic variant of conjunctival malignant melanoma is extremely rare and can be difficult to diagnose. But clinicians must be vigilant when changes in the conjunctiva and eyelids are noticed.

Liquid biopsy may help predict cancer-associated VTE

Liquid biopsies could help to identify patients with cancer who have an increased risk for venous thromboembolism.

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At a glance: The KEYNOTE lung cancer trials

Lung Cancer Clinical Trial Summary

A quick guide to the KEYNOTE trials investigating the anti-PD-1 agent pembrolizumab in non-small-cell and small-cell lung cancer.

Developed by: Springer Medicine
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SPONSORED

Challenges in advanced Cutaneous T-cell Lymphoma (CTCL) – diagnosis and management

Webinar | 10-06-2024 | 16:30 (CEST)

A multidisciplinary team of speakers provide practical guidance on managing patients with cutaneous T-cell lymphoma. 

Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare
Watch now to earn CME points

Case Studies

Concurrent pulmonary cryptococcosis and lung cancer

Open Access Cryptococcosis Case Study

This case serves as a prompt to consider the possibility of cryptococcosis, even when lung cancer has already been diagnosed, when lung radiology shows multiple nodules.

Uncommon type of malignant melanoma

Open Access Melanoma Case Study

The amelanotic variant of conjunctival malignant melanoma is extremely rare and can be difficult to diagnose. But clinicians must be vigilant when changes in the conjunctiva and eyelids are noticed.

Ablation of thyroid cancer: a double-edged sword?

Open Access Thyroid Cancer Case Study

Thyroid ablation technology has developed rapidly in the past 20 years, but these two cases highlight how incomplete ablation of thyroid nodules hinders its use as a treatment for thyroid cancer.

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
Listen now

Current Reviews

A Holistic Approach to Implementing Artificial Intelligence in Lung Cancer

The application of artificial intelligence (AI) in lung cancer, particularly in surgical approaches, has significantly transformed the healthcare landscape. AI has demonstrated remarkable advancements in early lung cancer detection, precise …

VEXAS Syndrome: A Review for the Inpatient Dermatologist

VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a rare adult-onset progressive autoinflammatory condition recently characterized by the NIH in 2020 [ 1 ]. UBA1 encodes for the main E1-activating enzyme that is …

NK/DC crosstalk-modulating antitumor activity via Sema3E/PlexinD1 axis for enhanced cancer immunotherapy

The complex relationship between natural killer (NK) cells and dendritic cells (DCs) within the tumor microenvironment significantly impacts the success of cancer immunotherapy. Recent advancements in cancer treatment have sought to bolster innate …

A dual biomarker in non-small cell lung cancer that predicts Li Fraumeni syndrome

NSCLC Review Article

Non-small cell lung cancer is the most common cause of cancer death globally. When apparent incidental pathogenic germline variants (PGVs) are uncovered with routine next generation sequencing (NGS) of NSCLCs, germline testing (GT) is recommended …

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Webinar | 19-02-2024 | 17:30 (CET)

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
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CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME

eLearning (Link opens in a new window)

The evolving landscape of metastatic urothelial carcinoma brings with it many challenges, such as optimally sequencing therapies and managing adverse events. Navigate your way through these with the Ultimate mUC challenge game and expert-to-expert interviews.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany and Astellas
Developed by: Springer Healthcare IME

Further Reading

MRI-based prediction of the need for wide resection margins in patients with single hepatocellular carcinoma

Open Access Hepatocellular Carcinoma Magnetic Resonance

Surgical resection constitutes a major curative-intent treatment option for resectable hepatocellular carcinoma (HCC) [ 1 ]. One of the main challenges in the surgical planning of HCC is to determine the appropriate resection margin to ensure …

PD-L1 and VEGF dual blockade enhances anti-tumor effect on brain metastasis in hematogenous metastasis model

Open Access Metastasis Research

Immunotherapy improves survival outcomes in cancer patients, but there is still an unmet clinical need in the treatment of brain metastases. Here, we used a mouse model to investigate the antitumor effect of programmed death-ligand 1 (PD-L1) and …

Potential prognostic biomarker SERPINA12: implications for hepatocellular carcinoma

Open Access Hepatocellular Carcinoma RESEARCH ARTICLE

Liver cancer is the fifth most common form of cancer and the fourth leading cause of cancer-related death. The most frequent tumor type is hepatocellular carcinoma (HCC), which accounts for more than 80% of primary liver cancer events worldwide [ 1 …]. It is projected that by the year 2040, an estimated 1.3 million people could die from liver cancer, representing a 56.4% increase compared to the figures reported in 2020 [

PCMT1 as a prognostic marker in breast cancer

Open Access Breast Cancer RESEARCH ARTICLE

Breast cancer accounts for 20–30% of all cancer cases in women and is the most often diagnosed malignancy in females [ 1 ]. Its subtype, called triple-negative breast cancer (TNBC), is characterized by the lack of human epidermal growth factor …

Related topics

Insufficient dosing of TKIs in CML

Open Access Chronic Myeloid Leukemia Case Study

In four patients with chronic myeloid leukemia and a history of bariatric surgery, TKI concentrations were found to be subtherapeutic, and all needed TKI switches and/or dose modifications to achieve a response.

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Advances in treating pLGG

Free for a limited time Glioma in Children Review

Pediatric low-grade gliomas often cause long-term morbidities despite high overall survival rates. But advances in molecular characterization, targeted therapies, and surgical techniques are improving management and outcomes.

Read more