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Chemotherapy-associated coronary thrombosis in breast cancer

This case of subacute inferolateral myocardial infarction secondary to coronary thrombosis occurring after adjuvant doxorubicin–cyclophosphamide therapy in a patient with breast cancer underscores the need for vigilance for uncommon, yet life-threatening, complications.

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Editor's Choice

Menstrual blood eases HPV screening for cervical cancer

HPV testing of self-collected menstrual blood is as effective as conventional cervical screening for the detection of grade 2 or higher cervical intraepithelial neoplasia.

Advances in bispecific ADCs for breast cancer

Bispecific antibody–drug conjugates represent a promising strategy to overcome the limitations of conventional ADCs in breast cancer, such as tumor heterogeneity and inefficient internalization.

Endarterectomy for radiation-induced carotid stenosis

In a patient with severe fibrosis and adhesion in the neck tissues 4 years after hypopharyngeal cancer therapy, thorough preoperative evaluation and precise surgical technique improved perfusion and resolved neurological symptoms.

High lifetime alcohol intake tied to elevated risk for CRC

Analysis of data from the PLCO cancer screening trial has revealed a significant association between higher lifetime drinking and an increased risk for colorectal cancer.

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Keynote webinar | Spotlight on progress in colorectal cancer

CRC remains a major global health burden, but advances in screening, treatment, and lifestyle-based prevention continue to reshape clinical practice. Gain insights into how the latest research can be leveraged to optimize patient care across the CRC continuum.

Prof. Antoni Castells
Prof. Harpreet Wasan
Prof. Edward Giovannucci
Watch now
COMMISSIONED

How-to guide for healthcare professionals: understanding genomic reports

This educational activity was initiated, funded and co-developed by Boehringer Ingelheim and is intended for healthcare professionals in the UK and Ireland only. 

Genomic testing helps inform cancer diagnosis, prognosis, and treatment. A genomic report is generated by the laboratory carrying out next-generation sequencing to analyze biopsy samples. Access this educational microsite to learn more about typical genomic report content and how to interpret test results for patients with cancer.

NP-GB-106631 | Jan 2026

Commissioned by:
  • Boehringer Ingelheim
Learn more

Case Studies

Chemotherapy-associated coronary thrombosis in breast cancer

This case of subacute inferolateral myocardial infarction secondary to coronary thrombosis occurring after adjuvant doxorubicin–cyclophosphamide therapy in a patient with breast cancer underscores the need for vigilance for uncommon, yet life-threatening, complications.

Endarterectomy for radiation-induced carotid stenosis

In a patient with severe fibrosis and adhesion in the neck tissues 4 years after hypopharyngeal cancer therapy, thorough preoperative evaluation and precise surgical technique improved perfusion and resolved neurological symptoms.

Localized bile duct stricture mimicking cholangiocarcinoma

A case of eosinophilic cholangitis presenting as a localized biliary stricture in a 65-year-old man. As perihilar cholangiocarcinoma could not be ruled out, the patient opted for surgical intervention.

Episode 25: Therapeutic cancer vaccines

The next frontier in cancer treatment?

Recently there has been a renewed interest in the prospect of therapeutic cancer vaccines. But what exactly does it mean to vaccinate against cancer, where are vaccines showing the most promise, and what are the challenges of making such vaccines a reality?

Dr. Elias Sayour answers these questions and more in this episode.

Dr. Elias Sayour
Listen now
Podcast

Current Reviews

Contrast-enhanced ultrasound for precise differentiation of hepatitis-related intrahepatic cholangiocarcinoma and hepatocellular carcinoma

Chronic viral hepatitis infection is the primary etiology of primary liver cancer (PLC), with distinct geographical distributions. In East Asia and Africa, hepatitis B virus (HBV) is the predominant cause [ 1 , 2 ]. Notably, chronic HBV infection …

Nurse-Led Educational Interventions Significantly Improve Treatment Adherence and Psychosocial Outcomes in Chemotherapy Patients: A Meta-analysis

Adherence to chemotherapy is a key determinant of clinical outcomes [ 1 ]. However, despite advancements in oncology care, nonadherence remains widespread and is associated with increased morbidity, mortality, and healthcare expenditures. Common …

Assessing frailty-related risk in older patients in hematology and oncology

The increasing prevalence of cancer among older adults underscores the need for individualized therapy approaches. Chronological age alone is insufficient to guide oncological decision-making, as comorbidities, frailty, and functional status vary …

Genomic alterations and their correlation with metabolic-related genes in lung cancer

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related mortality worldwide, with 5-year survival rates below 21% primarily due to therapeutic resistance and metastatic progression. Genomic alterations in KRAS, EGFR, TP53 …

Aplastic anemia: managing special patient subgroups and challenging cases (Link opens in a new window)

Learn more about the importance of adapting treatment approaches for special patient populations (eg, elderly or pregnant patients) in this third module of our interactive e-Learning program on diagnosing and treating aplastic anemia.

Supported by:
  • Pfizer
Developed by: Springer Health+ IME
Learn more

CME & eLearning

COMMISSIONED

How-to guide for healthcare professionals: understanding genomic reports

This educational activity was initiated, funded and co-developed by Boehringer Ingelheim and is intended for healthcare professionals in the UK and Ireland only.

Genomic testing helps inform cancer diagnosis, prognosis, and treatment. Access this educational microsite to learn more about typical genomic report content and how to interpret test results for patients with cancer.

NP-GB-106631 | Jan 2026

Commissioned by:
  • Boehringer Ingelheim
SPONSORED

Masterclass webinar: Expert review of CAR T-cell therapy patient cases in R/R DLBCL or R/R FL

Professor Joy Ho and a panel of Asia-Pacific-based experts will examine real-life patient cases in this Masterclass, exchanging insights into their clinical experiences of using CAR T-cell therapy to treat patients with R/R DLBCL or R/R FL.

This educational activity is not intended for healthcare professionals based in the UK, US, or off-label Asia-Pacific countries.

Sponsor:
  • Novartis Pharma AG
SPONSORED

CAR T-cell therapy medical education hub

This hub presents a curated selection of educational materials focused on the latest clinically relevant topics related to the use of chimeric antigen receptor (CAR) T‑cell therapy for the treatment of relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and R/R follicular lymphoma (FL).

This content has been developed in collaboration with and funded by the sponsor Novartis Pharma AG and is not intended for healthcare professionals based in the UK and US.

Sponsor:
  • Novartis Pharma AG

Further Reading

Long-Term Results of Multiple Pulmonary Metastasectomies

  • Open Access
  • Metastasis
  • Thoracic Oncology and Esophageal Cancer

HER2 testing in multiple solid tumor types: concordance of immunohistochemistry scores between three HER2 scoring algorithms

Accurate human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) scoring is crucial to identify patients for HER2-directed therapy; however, validated HER2 scoring guidelines are lacking for non-breast/gastric solid tumors. We …

Exploring extended [18F]FDG kinetics in lymphoma with ultra-late LAFOV-PET/CT

Positron emission tomography (PET) using [18F]fluorodeoxyglucose ([ 18 F]FDG) has become the method of choice in the staging and therapeutic response assessment of malignant lymphoma [ 1 – 8 ]. International guidelines recommend [ 18 F]FDG PET/CT …

Assessment of liver fibrosis and tumor burden in hepatocellular carcinoma using [18F]AlF-NOTA-FAPI-04 PET/CT: a prospective study

Hepatocellular carcinoma (HCC) has emerged as the third leading cause of cancer-related mortality worldwide and ranks among the top malignancies in many national cancer statistics [ 1 ]. The development of HCC is closely associated with the …

Related topics

Portal hypertension following inotuzumab treatment

Long-term monitoring for portal hypertension is important – even after resolution of acute sinusoidal obstruction syndrome and achievement of leukemia remission – to optimize outcomes in inotuzumab ozogamicin-treated patients.

Read more

Chemotherapy-associated coronary thrombosis in breast cancer

This case of subacute inferolateral myocardial infarction secondary to coronary thrombosis occurring after adjuvant doxorubicin–cyclophosphamide therapy in a patient with breast cancer underscores the need for vigilance for uncommon, yet life-threatening, complications.

Read more
Image Credits
Angiography showing total occlusion of LAD and LCX/© 2026, Oya Imadoglu et al, BMC Cardiovasc Disord, Lab technician loading centrifuge/© sinology / Moment / Getty, Bispecific antibody-drug conjugates/© 2026, Xuan Ji et al, Cancer Chemother Pharmacol, Intraoperative photo of carotid endarterectomy/© 2026, Mingyang Qiu et al, J Med Case Reports, Assortment of glasses of wine and beer/© MarkWagonerProductions / Getty Images / iStock, Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images, Transparent pink and clear capsules/© mitand73 / stock.adobe.com, Patient taking a color blindness test/© rudi_suardi / Getty Images / iStock, Man standing in a supermarket aisle and reading the label on a grocery item/© Giselleflissak / Getty Images / iStock (symbolic image with model), Older man sitting on the edge of a bed/© andreswd / E+ / Getty Images (symbolic image with model), DNA double helix structure on a purple background/© 2025 Adobe, Peroral cholangioscopy at a hepatic hilar bile duct stricture/© 2026, Takeshi Mori et al, Clin J Gastroenterol, under exclusive licence to Japanese Society of Gastroenterology, Medicine Matters Podcast promo image/© Springer Medizin GmbH, Aplastic Anemia/© Springer Healthcare IME, CAR T-cell attacking cancer cells/© LoveLive/stock.adobe.com, T-cell expressing chimeric antigen receptor (CAR) in the cell membrane; DNA is exposed from the T-cell to highlight the genetic engineering involved in creating CAR T-cells/© LoveLive/stock.adobe.com, IV drip/© Trsakaoe / stock.adobe.com, FDG PET-CT of patient with Behçet disease and Hodgkin lymphoma/© 2025, Matthew Coulter et al, under exclusive licence to International League of Associations for Rheumatology (ILAR), Clin Rheumatol, Fundus scan in vitreoretinal lymphoma/© 2025, Atsunobu Takeda et al, Jpn J Ophthalmol, Antibody drug conjugates/© huenstructurebio.com / stock.adobe.com, Close-up of subcutaneous injection syringe/© Laures / Getty Images / iStock