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Add-on Ra223 could be a new first-line option in mCRPC

Adding radium-223 to first-line enzalutamide significantly improves the survival of patients with bone metastatic castration-resistant prostate cancer.

Read more

Editor's Choice

FITs performance variable for detection of colorectal neoplasia

Fecal immunohistochemical tests should not be considered interchangeable due to significant differences in the ability to detect advanced colorectal neoplasia.

Gut microbiota and leukemia: a causal relationship?

Explore the intricate relationship between the gut microbiota and leukemia, including potentially causal associations that could open new avenues for prevention and treatment.

ICI-induced encephalitis in a patient with HCC

Only the third reported case of encephalitis in a patient receiving atezolizumab plus bevacizumab for advanced hepatocellular carcinoma. The neurological symptoms quickly improved once steroid pulse therapy was started.

Cardiometabolic risks in cancer survivorship

Managing cardiometabolic health in patients with a history of cancer is increasingly important. Discover the primary considerations including impact of demographic variables, cancer types, and treatment modalities. 

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2024 ESMO Congress

SPONSORED

Challenges in advanced Cutaneous T-cell Lymphoma (CTCL) – diagnosis and management

  • Webinar | 10-06-2024 | 16:30 (CEST)

A multidisciplinary team of speakers provide practical guidance on managing patients with cutaneous T-cell lymphoma. 

Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare
Watch now to earn CME points

Case Studies

ICI-induced encephalitis in a patient with HCC

Only the third reported case of encephalitis in a patient receiving atezolizumab plus bevacizumab for advanced hepatocellular carcinoma. The neurological symptoms quickly improved once steroid pulse therapy was started.

Concurrent pulmonary cryptococcosis and lung cancer

This case serves as a prompt to consider the possibility of cryptococcosis, even when lung cancer has already been diagnosed, when lung radiology shows multiple nodules.

Uncommon type of malignant melanoma

The amelanotic variant of conjunctival malignant melanoma is extremely rare and can be difficult to diagnose. Clinicians must be vigilant when changes in the conjunctiva and eyelids are noticed.

At a glance: The KEYNOTE lung cancer trials

A quick guide to the KEYNOTE trials investigating the anti-PD-1 agent pembrolizumab in non-small-cell and small-cell lung cancer.

Developed by: Springer Medicine
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Current Reviews

Dietary Recommendations for Glioma: A Mini-Review

Cancer remains a critical challenge within the healthcare system, contributing to high mortality rates worldwide [ 1 ]. Among the various types of cancer, glioma is the most common brain cancer, originating in glial cells [ 2 ]. Glioma is often …

Natural killer cells in neuroblastoma: immunological insights and therapeutic perspectives

Natural killer (NK) cells have multifaceted roles within the complex tumor milieu. They are pivotal components of innate immunity and shape the dynamic landscape of tumor-immune cell interactions, and thus can be leveraged for use in therapeutic …

Emerging immunologic approaches as cancer anti-angiogenic therapies

Targeting tumor angiogenesis, the formation of new blood vessels supporting cancer growth and spread, has been an intense focus for therapy development. However, benefits from anti-angiogenic drugs like bevacizumab have been limited by resistance …

Safety profile of trastuzumab originator vs biosimilars: a systematic review and meta-analysis of randomized clinical trials

Breast cancer is the most commonly diagnosed cancer among females with over 2 million new cases in 2018. Moreover, it is the leading cause of cancer death (626,679 deaths per year) [ 1 ]. Different modern therapeutic strategies are available to …

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
Listen now

CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME

eLearning (Link opens in a new window)

The evolving landscape of metastatic urothelial carcinoma brings with it many challenges, such as optimally sequencing therapies and managing adverse events. Navigate your way through these with the Ultimate mUC challenge game and expert-to-expert interviews.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany and Astellas
Developed by: Springer Healthcare IME

Further Reading

CRAFITY score as a predictive marker for refractoriness to atezolizumab plus bevacizumab therapy in hepatocellular carcinoma: a multicenter retrospective study

Hepatocellular carcinoma (HCC) ranks among the most common malignant tumors globally and stands as the third leading cause of cancer-related deaths [ 1 ]. In recent years, various molecular targeted agents have received approval for either first- [ …2

MRI features of histological subtypes of thyroid cancer in comparison with CT findings: differentiation between anaplastic, poorly differentiated, and papillary thyroid carcinoma

Thyroid cancer is the ninth most common type of cancer worldwide. Approximately 75% of patients with thyroid cancer are females, and the median age of diagnosis is in the early 50 s. Furthermore, this disease is the most common malignancy in the …

Natural killer cells in neuroblastoma: immunological insights and therapeutic perspectives

Natural killer (NK) cells have multifaceted roles within the complex tumor milieu. They are pivotal components of innate immunity and shape the dynamic landscape of tumor-immune cell interactions, and thus can be leveraged for use in therapeutic …

A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin

Cancer of unknown primary (CUP) is a poor prognostic malignancy with an unknown primary site and histologically known metastases[ 1 – 4 ]. Most patients with CUP, except for about 20% with favorable prognostic factors, receive empiric chemotherapy …

Related topics

Gut microbiota and leukemia: a causal relationship?

Explore the intricate relationship between the gut microbiota and leukemia, including potentially causal associations that could open new avenues for prevention and treatment.

Read more

Add-on Ra223 could be a new first-line option in mCRPC

Adding radium-223 to first-line enzalutamide significantly improves the survival of patients with bone metastatic castration-resistant prostate cancer.

Read more