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Circadian rhythms and breast cancer

What role do circadian rhythms have in the occurrence and development of breast cancer? And how can they be leveraged to enhance treatment efficacy and improve patient outcomes?

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Editor's Choice

Is heart failure a risk factor for cancer?

The causal effect of cancer and cancer therapies on the development of heart failure is well known, but what about the other way around? Explore the evidence for the pathophysiological pathways linking tumor growth with heart failure.

CAR T-cell therapy for CML in blast phase

A 16-year-old with repeatedly relapsing chronic myeloid leukemia in blast phase achieved a durable response to CAR T-cell therapy when multiple previous treatments had led only to short-term molecular remissions.

Key tests for diagnosing pLGG

Detailed pathological diagnosis – based on a combination of histology, methylation profiling, and sequencing – provides the optimal basis for deciding how to treat pediatric low-grade gliomas.

Tumor microenvironment and management of medullary thyroid cancer

The absence or presence of primary tumor desmoplasia may be an alternative to conventional classification systems to help guide intraoperative management of sporadic medullary thyroid cancer.

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2024 ESMO Congress

SPONSORED

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

  • Webinar | 01-10-2024 | 12:30 (CEST)

In this webinar, Professor Martin Dreyling and an esteemed international panel of CAR T-cell therapy experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by:
  • Novartis Pharma AG
Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
Get a reminder for the on-demand version

Case Studies

CAR T-cell therapy for CML in blast phase

A 16-year-old with repeatedly relapsing chronic myeloid leukemia in blast phase achieved a durable response to CAR T-cell therapy when multiple previous treatments had led only to short-term molecular remissions.

Exceptionally rare manifestation of papillary thyroid cancer

Spontaneous hepatic hemorrhage is a rare condition that is mostly seen in patients with hepatocellular carcinoma or hepatic adenomas. But in this case it was caused by metastasized papillary thyroid cancer.

Worsening heart failure in a survivor of cancer as a young adult

Severe cardiomyopathy presenting 20 years after anthracycline treatment for non-Hodgkin’s lymphoma during early adulthood. The patient's worsening heart failure was successfully managed with multidrug treatment with add-on vericiguat and ivabradine based on quadruple therapy. 

At a glance: The KEYNOTE lung cancer trials

A quick guide to the KEYNOTE trials investigating the anti-PD-1 agent pembrolizumab in non-small-cell and small-cell lung cancer.

Developed by: Springer Medicine
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Current Reviews

Advanced imaging techniques and non-invasive biomarkers in pediatric brain tumors: state of the art

In the pediatric age group, brain neoplasms are the second most common tumor category after leukemia, with an annual incidence of 6.13 per 100,000. Conventional MRI sequences, complemented by CT whenever necessary, are fundamental for the initial …

An Adjustable Positivity Threshold for Non-invasive Screening Tests for Colorectal Neoplasms Can Improve Screening Program Effectiveness and Feasibility

The effectiveness of two-step screening for colorectal cancer (CRC)—which initially uses a non-invasive test to identify individuals at higher risk of CRC, followed by a diagnostic colonoscopy for those identified—has been proven to reduce …

ESR Essentials: staging and restaging with FDG-PET/CT in oncology—practice recommendations by the European Society for Hybrid, Molecular and Translational Imaging

Proper selection of patients: Before deciding whether or not to perform a [ 18 F]FDG-PET/CT, carefully evaluate its appropriateness for the corresponding indication based on specific clinical criteria and existing evidence. [ 18 F]FDG-PET/CT should …

Adjuvant endocrine therapy and risk of contralateral breast cancer: a systematic review and meta-analysis of observational studies

Increases in the incidence of breast cancer, in particular, estrogen receptor (ER)-positive breast cancer [ 1 ] among women in the United States, in parallel with a steady rise in survival [ 2 , 3 ], place a growing population at high risk for …

Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
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CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

A series of patient cases underpin this interactive webinar that aims to provide practical guidance on a multidisciplinary approach to managing patients with cutaneous T-cell lymphoma.

Sponsored by:
  • Kyowa Kirin
Developed by: Springer Healthcare

Symposium (Link opens in a new window)

An independent symposium at the 10th COMy World Congress focusing on BCMA-targeting strategies for the treatment of multiple myeloma. Gain insights into the latest clinical data and the implications for clinical practice.

Supported by:
  • GlaxoSmithKline
Developed by: Springer Healthcare IME

eLearning (Link opens in a new window)

The evolving landscape of metastatic urothelial carcinoma brings with it many challenges, such as optimally sequencing therapies and managing adverse events. Navigate your way through these with the Ultimate mUC challenge game and expert-to-expert interviews.

Supported by:
  • Merck Healthcare KGaA, Darmstadt, Germany and Astellas
Developed by: Springer Healthcare IME

Further Reading

Follicular dendritic cell sarcoma involving the parotid gland with expression of the melanocytic marker PRAME

Follicular dendritic cell sarcoma is a rare mesenchymal neoplasm arising from follicular dendritic cells (FDC) of lymphoid follicles. While the majority of FDC sarcoma cases arise within lymph nodes, approximately 30% manifest in extranodal sites.

An Adjustable Positivity Threshold for Non-invasive Screening Tests for Colorectal Neoplasms Can Improve Screening Program Effectiveness and Feasibility

The effectiveness of two-step screening for colorectal cancer (CRC)—which initially uses a non-invasive test to identify individuals at higher risk of CRC, followed by a diagnostic colonoscopy for those identified—has been proven to reduce …

ESR Essentials: staging and restaging with FDG-PET/CT in oncology—practice recommendations by the European Society for Hybrid, Molecular and Translational Imaging

Proper selection of patients: Before deciding whether or not to perform a [ 18 F]FDG-PET/CT, carefully evaluate its appropriateness for the corresponding indication based on specific clinical criteria and existing evidence. [ 18 F]FDG-PET/CT should …

Preoperative evaluation of the segmental artery of left upper lobe by thin-section CT and 3d-CTA

Knowledge of pulmonary artery (PA) branching patterns is crucial for thoracic surgeons due to potential bleeding complications during pulmonary resection. Anatomic PA branching pattern variations in the left upper lobe are more common than the …

Related topics

CAR T-cell therapy for CML in blast phase

A 16-year-old with repeatedly relapsing chronic myeloid leukemia in blast phase achieved a durable response to CAR T-cell therapy when multiple previous treatments had led only to short-term molecular remissions.

Read more

Circadian rhythms and breast cancer

What role do circadian rhythms have in the occurrence and development of breast cancer? And how can they be leveraged to enhance treatment efficacy and improve patient outcomes?

Read more