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Published in: European Radiology 11/2023

22-09-2023 | Commentary

No incision required for long-lasting symptom relief in a selection of women suffering from uterine fibroids

Authors: Derk J. Slotman, Ingrid M. Nijholt, Joke M. Schutte, Martijn F. Boomsma

Published in: European Radiology | Issue 11/2023

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Excerpt

MRI-guided focused ultrasound (MRgFUS) offers an excellent non-invasive uterus-sparing treatment option for a selection of women with symptomatic uterine fibroids. MRgFUS involves precise thermal ablation of target tissue by focused ultrasound waves, guided by MRI to monitor temperature and anatomy, sparing surrounding structures. As a multidisciplinary, non-invasive, image-guided therapy, it aligns perfectly with several of radiology’s and gynecology’s missions for the future [ 1, 2]. The main advantages of MRgFUS, in addition to its non-invasive nature, are exceptionally short recovery times and low rates of periprocedural complications compared to mainstay treatments such as hysterectomy, myomectomy, and uterine artery embolization [ 3, 4]. Several single-center cohort studies have demonstrated MRgFUS to be safe and effective, but multicenter studies with long-term follow-up of clinical outcomes in terms of symptom relief and re-intervention rate are scarce [ 3, 5]. …
Literature
1.
go back to reference Radiological Society of the Netherlands (2021) Strategic Vision ’21-’30: Radiology, The Navigator Of Healthcare Radiological Society of the Netherlands (2021) Strategic Vision ’21-’30: Radiology, The Navigator Of Healthcare
2.
go back to reference Dutch Society of Obstetrics and Gynaecology (2019) Vision Statement: Gynaecologist 2025 Dutch Society of Obstetrics and Gynaecology (2019) Vision Statement: Gynaecologist 2025
3.
go back to reference Pron G (2015) Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) treatment of symptomatic uterine fibroids: an evidence-based analysis. Ont Health Technol Assess Ser 15:1–86 PubMedPubMedCentral Pron G (2015) Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) treatment of symptomatic uterine fibroids: an evidence-based analysis. Ont Health Technol Assess Ser 15:1–86 PubMedPubMedCentral
4.
go back to reference Gao H, Li T, Fu D, Wei J (2021) Uterine artery embolization, surgery and high intensity focused ultrasound in the treatment of uterine fibroids: a network meta-analysis. Quant Imaging Med Surg 11:4125–4136 CrossRefPubMedPubMedCentral Gao H, Li T, Fu D, Wei J (2021) Uterine artery embolization, surgery and high intensity focused ultrasound in the treatment of uterine fibroids: a network meta-analysis. Quant Imaging Med Surg 11:4125–4136 CrossRefPubMedPubMedCentral
5.
go back to reference Verpalen IM, Anneveldt KJ, Nijholt IM et al (2019) Magnetic resonance-high intensity focused ultrasound (MR-HIFU) therapy of symptomatic uterine fibroids with unrestrictive treatment protocols: a systematic review and meta-analysis. Eur J Radiol 120:108700 CrossRefPubMed Verpalen IM, Anneveldt KJ, Nijholt IM et al (2019) Magnetic resonance-high intensity focused ultrasound (MR-HIFU) therapy of symptomatic uterine fibroids with unrestrictive treatment protocols: a systematic review and meta-analysis. Eur J Radiol 120:108700 CrossRefPubMed
7.
go back to reference Verpalen IM, de Boer JP, Linstra M et al (2020) The Focused Ultrasound Myoma Outcome Study (FUMOS); a retrospective cohort study on long-term outcomes of MR-HIFU therapy. Eur Radiol 30:2473–2482 CrossRefPubMed Verpalen IM, de Boer JP, Linstra M et al (2020) The Focused Ultrasound Myoma Outcome Study (FUMOS); a retrospective cohort study on long-term outcomes of MR-HIFU therapy. Eur Radiol 30:2473–2482 CrossRefPubMed
8.
go back to reference Xu F, Deng L, Zhang L, Hu H, Shi Q (2021) The comparison of myomectomy, UAE and MRgFUS in the treatment of uterine fibroids: a meta analysis. Int J Hyperth Off J Eur Soc Hyperthermic Oncol North Am Hyperth Gr 38:24–29 CrossRef Xu F, Deng L, Zhang L, Hu H, Shi Q (2021) The comparison of myomectomy, UAE and MRgFUS in the treatment of uterine fibroids: a meta analysis. Int J Hyperth Off J Eur Soc Hyperthermic Oncol North Am Hyperth Gr 38:24–29 CrossRef
9.
go back to reference Keserci B, Duc NM (2017) The role of T1 perfusion-based classification in magnetic resonance-guided high-intensity focused ultrasound ablation of uterine fibroids. Eur Radiol 27:5299–5308 CrossRefPubMed Keserci B, Duc NM (2017) The role of T1 perfusion-based classification in magnetic resonance-guided high-intensity focused ultrasound ablation of uterine fibroids. Eur Radiol 27:5299–5308 CrossRefPubMed
10.
go back to reference Mindjuk I, Trumm CG, Herzog P, Stahl R, Matzko M (2015) MRI predictors of clinical success in MR-guided focused ultrasound (MRgFUS) treatments of uterine fibroids: results from a single centre. Eur Radiol 25:1317–1328 CrossRefPubMed Mindjuk I, Trumm CG, Herzog P, Stahl R, Matzko M (2015) MRI predictors of clinical success in MR-guided focused ultrasound (MRgFUS) treatments of uterine fibroids: results from a single centre. Eur Radiol 25:1317–1328 CrossRefPubMed
11.
go back to reference Suomi V, Komar G, Sainio T, Joronen K, Perheentupa A, Blanco Sequeiros R (2019) Comprehensive feature selection for classifying the treatment outcome of high-intensity ultrasound therapy in uterine fibroids. Sci Rep 9:10907 CrossRefPubMedPubMedCentral Suomi V, Komar G, Sainio T, Joronen K, Perheentupa A, Blanco Sequeiros R (2019) Comprehensive feature selection for classifying the treatment outcome of high-intensity ultrasound therapy in uterine fibroids. Sci Rep 9:10907 CrossRefPubMedPubMedCentral
13.
go back to reference Funaki K, Fukunishi H, Funaki T, Sawada K, Kaji Y, Maruo T (2007) Magnetic resonance-guided focused ultrasound surgery for uterine fibroids: relationship between the therapeutic effects and signal intensity of preexisting T2-weighted magnetic resonance images. Am J Obstet Gynecol 196:184.e1-184.e6 CrossRefPubMed Funaki K, Fukunishi H, Funaki T, Sawada K, Kaji Y, Maruo T (2007) Magnetic resonance-guided focused ultrasound surgery for uterine fibroids: relationship between the therapeutic effects and signal intensity of preexisting T2-weighted magnetic resonance images. Am J Obstet Gynecol 196:184.e1-184.e6 CrossRefPubMed
14.
go back to reference Jeong J-H, Hong GP, Kim Y-R, Ha J-E, Lee K-S (2016) Clinical consideration of treatment to ablate uterine fibroids with magnetic resonance imaging-guided high intensity focused ultrasound (MRgFUS): Sonalleve. J Menopausal Med 22:94–107 CrossRefPubMedPubMedCentral Jeong J-H, Hong GP, Kim Y-R, Ha J-E, Lee K-S (2016) Clinical consideration of treatment to ablate uterine fibroids with magnetic resonance imaging-guided high intensity focused ultrasound (MRgFUS): Sonalleve. J Menopausal Med 22:94–107 CrossRefPubMedPubMedCentral
15.
go back to reference Anneveldt KJ, Nijholt IM, Schutte JM et al (2021) Comparison of (cost-)effectiveness of magnetic resonance image-guided high-intensity-focused ultrasound with standard (minimally) invasive fibroid treatments: protocol for a multicenter randomized controlled trial (MYCHOICE). JMIR Res Protoc 10:e29467 CrossRefPubMedPubMedCentral Anneveldt KJ, Nijholt IM, Schutte JM et al (2021) Comparison of (cost-)effectiveness of magnetic resonance image-guided high-intensity-focused ultrasound with standard (minimally) invasive fibroid treatments: protocol for a multicenter randomized controlled trial (MYCHOICE). JMIR Res Protoc 10:e29467 CrossRefPubMedPubMedCentral
Metadata
Title
No incision required for long-lasting symptom relief in a selection of women suffering from uterine fibroids
Authors
Derk J. Slotman
Ingrid M. Nijholt
Joke M. Schutte
Martijn F. Boomsma
Publication date
22-09-2023
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 11/2023
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-023-10197-y

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