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Neurological Sciences

Issue 9/2025

Content (79 Articles)

Diagnostic utility of electrophysiological markers for early and differential diagnosis of Alzheimer’s, Frontotemporal, and Lewy Body dementias: A systematic review

Stéphanie De Keulenaer, Sara Van Mossevelde, Tobi Van den Bossche, David Crosiers, Patrick Cras, Tommas Ellender, Rose Bruffaerts

The Role and Mechanisms of G protein-coupled receptors in Parkinson's disease

Yajun Jing, Peisen Yao, Honglin Zhu, Lianghong Yu, Yuanxiang Lin, Dezhi Kang

Efficacy and safety of continuous subcutaneous ND0612 Infusion compared to oral and alternative regimens in managing motor fluctuations in Parkinson’s disease: a systematic review and meta-analysis

Abdallah Abunamoos, Mohammad Moayad Ahmad Alghaniem, Fares A. Qtaishat, Yumna Aljazi, Leen Omar Al-Omari, IZERE Salomon, Bara M. Hammadeh, Khaled Moghib

Exploring the role of melatonin in managing sleep and motor symptoms in Parkinson’s disease: a pooled analysis of double-blinded randomized controlled trials

Ahmed Samy Badran, Hamza Khelifa, Mohamed Ibrahim Gbreel

Optimal dose and type of exercise improve the overall balance in adults with Parkinson’s disease: a systematic review and Bayesian network meta-analysis

Xianjin Fan, Yuan Yuan, Ying Bai, Chen Cheng, Junyu Wang, Tao Wang, Yong Yang, Ko-Chia Chen

Dopa-responsive dystonia and phenotypes associated with TH gene variants: a systematic review and Mexican case series

Carlos Ulises Lopez-Urias, Nancy Monroy-Jaramillo, Renee Barreda Fierro, Miguel Ángel Ramírez-García

A comprehensive and critical narrative review on movement disorders linked through dengue virus based infection

Niraj Kumar Srivastava, Nikhil Pandey, Janki Makani, Ibrahim Hussain, Neetu Rani Dhiman, Anand Kumar, Deepika Joshi

Co-occurence of amyotrophic lateral sclerosis and sarcoidosis: a case report and systematic review of the literature

Luigi Bonan, Marcello Bombardi, Andrea Di Lionardo, Maria Vitiello, Simonetta Morresi, Marco Longoni

Arginase 1 deficiency: a treatable form of spastic paraplegia

Alessandro Burlina, Anna Ardissone, Roberta Battini, Alberto Burlina, Serena Gasperini, Andrea Pession, Francesco Porta, Carlo Dionisi Vici

Effectiveness of physical rehabilitation approaches in improving function and mobility after stroke: comprehensive insights from a Cochrane systematic review

Chun Dang, Yaoheng Lu, Ying Xiong, Li Feng

Systematic review: Resting state functional MRI as a biomarker for non-invasive brain stimulation in upper limb recovery post-stroke

Mudasar Aziz, Sheharyar Baig, Wen Hai, Ali Ali, Arshad Majid, Li Su

Causal correlation between seizure activity and brain damage

Laura Librizzi, Diogo Vila Verde, Marco de Curtis

Acute bilateral optic/chiasm neuritis with longitudinally extensive transverse myelitis and positive anti-ganglioside antibodies following mycoplasma pneumoniae pneumonia: a case report and literature review

Juan Zhao, Nan Jia, Jiabao Zhao, Jiawei Wang, Liping Zhu

Recent advances in diagnostic technologies for postoperative central nervous system infections: a review

Junan Hu, Wei Yu, Jiating Cui, Lun Zhang, Wangfang Yu

Pro-inflammatory cytokines in myasthenia gravis: a systematic review and meta-analysis

Ali Shushtari, Hamidreza Ashayeri, Amirhossein Salmannezhad, Homa Seyedmirzaei, Nima Rezaei

Neurocognitive assessment in relation to hearing impairment and retinal neurodegeneration

Chan Ho Lee, Jae-Ik Kim, Kang Min Lee, Joo Hyun Park, Kunho Bae

Beyond memory: leveraging CSF biomarkers in all MCI patients ahead of anti-amyloid therapies

Martina Poli, Chiara Giuseppina Bonomi, Luca Tretola, Marta Rosa, Martina Gaia Di Donna, Alessandra Moreschini, Marzia Nuccetelli, Sergio Bernardini, Nicola Biagio Mercuri, Alessandro Martorana, Caterina Motta

Postmortem neuropathologies are associated with retrospective tensor-based morphometry findings in Alzheimer’s dementia continuum

Amirmohammad Azizzadeh, Mahla Najafi, Zahra Nafar, Shahed Salehzehi, Sahba Azadikhah Jahromi, Hamed Fallah, Hamed Ghoshouni

Destination memory in behavioral-variant frontotemporal dementia

Mohamad el Haj, Dimitrios Kapogiannis, Claire Boutoleau-Bretonnière

“Assessing relationship between blood MAPT methylation levels and clinical expression in Frontotemporal Dementia”

Gemma Lombardi, Silvia Bagnoli, Assunta Ingannato, Alice Finocchi, Silvia Campagnini, Silvia Fostinelli, Antonio Longobardi, Roberta Ghidoni, Giuliano Binetti, Barbara Borroni, Jasmine Rivolta, Sonia Padiglioni, Valentina Bessi, Sandro Sorbi, Benedetta Nacmias

Exploring GBA1 gene in Parkinson's disease: Prevalence and variant spectrum from Asia minor

Merve Koç Yekedüz, Rezzak Yilmaz, Talha Abali, Sema Nur Kibrit, Ahmet Veli Karacan, Elif Yüsra Unutmaz, Gülnur Ayık, Dudu Genç-Batmaz, G. Rana Dilek, Binnur Çelik, Emine Gemci, Turgut Şahin, Ahmet Yalcin, Serdar Ceylaner, M. Cenk Akbostancı, Fatma Tuba Eminoğlu

Impaired glymphatic function assessed by DTI-ALPS in drug-naïve Parkinson’s disease and its association with motor and non-motor symptoms

Junying Li, Meiling Ding, Wenmin Zhang, Pan Yang, Yang Du, Weidong Wang, Jurong Ding, Xin Ding

Investigation of symptom-specific functional connectivity patterns in Parkinson’s disease

Ani Kicik, Ali Bayram, Emel Erdogdu, Elif Kurt, Dilek Betul Saridede, Sevim Cengiz, Basar Bilgic, Hasmet A. Hanagasi, Esin Ozturk-Isik, Hakan Gurvit, Erdem Tuzun, Tamer Demiralp

The evolution of tremor in Parkinson's Disease: insights from a 4-year longitudinal assessment

  • Open Access
  • Tremor
  • Original Article

Carolina Cutrona, Matteo Costanzo, Giorgio Leodori, Maria Ilenia De Bartolo, Agnese Liguori, Francesco Marchet, Marco Mancuso, Giorgio Vivacqua, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Daniele Belvisi

Ultrasonographic assessment of dysphagia in Parkinson’s disease: a controlled study

Büşra Şirin Ahısha, Nur Kesiktaş, Nurdan Paker

Correlation between Parkinson’s disease subtypes and plasma uric acid/neutrophil-to-lymphocyte ratio

Mei Ding, Han Wang, Jia Li, Xiangyang Zhu

Sarcopenia, malnutrition, and fatigue in de Novo Parkinson’s disease– support for early rehabilitation

Beata Lindholm, Ylva Dernbrant, Albert Westergren, Erika Franzen

Implications of the glymphatic system in the diagnostic and surgical workup of normal pressure hydrocephalus

Morgan Broggi, Edoardo M. Barbieri, Alessandro Gans, Pascuzzo Riccardo, Veronica Redaelli, Domenico Aquino, Francesco Restelli, Marco Schiariti, Francesco Acerbi, Giuseppe Di Fede, Paolo Ferroli, Marina Grisoli, Fabio Doniselli

Association of biological age acceleration with poor outcome after endovascular thrombectomy

Mingyue Qian, Wei Wang, Shuaiyu Chen, Yan E, Bin Wei, Lulu Liu, Jiayu Chen, Hao Wu

Application of bundle of care for spontaneous intracerebral hemorrhage in the real world: effect on hematoma expansion and functional outcome

Manuel Cappellari, Mara Zenorini, Bruno Bonetti

External validation of outcome prediction scores for aneurysmal subarachnoid hemorrhage in a real-world setting: a monocentric experience

Raffaele De Marco, Riccardo Melilli, Riccardo Russo, Mauro Bergui, Diego Garbossa, Fabio Cofano

Convexity subarachnoid hemorrhage after mechanical thrombectomy

Caixia Li, Tingyu Yi, Meihua Wu, Weifeng Huang, Shuyi Liu, Yining Yang, Jinhua Ye, Hua Jiang, Shujuan Gan, Wenhuo Chen

Unilateral contralesional versus bilateral repetitive transcranial magnetic stimulation for patients with post stroke dysphagia: a randomized controlled study

Basem Hamdy Fouda, Ahmed Mostafa Kishk

Seizure prediction in cerebral venous thrombosis– a retrospective single-centre observational study

Patrícia Faustino, Diana Melancia

Case report of ischemic stroke in a child secondary to neuroborreliosis

Dawid Zakrzewski, Mateusz Tomkiewicz, Wiktoria Kubziakowska, Marta Zawadzka, Jakub Szymarek, Maria Mazurkiewicz-Bełdzińska

Swallow sound acoustics: a cost-effective objective tool for swallowing assessment in individuals with neurogenic dysphagia

Syam Krishna Vijayan, Krishna Yeshoda

Anti-CGRP monoclonal antibodies, migraine and mood disorders: an observational study.

Marco Bolchini, Giulia Ceccardi, Francesca Schiano di Cola, Michele Di Pasquale, Renata Rao, Alessandro Padovani

Abnormalities of cortical morphology and structural covariance network in the patients with primary trigeminal neuralgia: a preliminary clinical study

Hui Xu, Li Jia, Yutao Wang, Wenjing Han, Dan Li, Ming Zhang, Yuan Wang

Changes in circulating pro-inflammatory lymphocytes and cortical excitability with extended-interval natalizumab dosing in multiple sclerosis

Marco Pisa, Tommaso Croese, Gloria Dalla Costa, Martina Congiu, Stefano Gelibter, Mario Orrico, Lucia Moiola, Giancarlo Comi, Roberto Furlan, Letizia Leocani

Intermittent theta burst stimulation improves spasticity, pain and cognitive functions in progressive multiple sclerosis: a pilot study

Rezzan Yildiz, Mehmet Ilker Yon, Tahir Kurtulus Yoldas, Evren Yasar, Elif Yalcin Topcuoglu, Funda Eren

Characteristics of pain in patients with NMOSD and MOGAD: impact on mental health, sleep and quality of life

Emine Rabia Koc, Furkan Saridas, Mehmet Fatih Yetkin, Nuray Bilge, Yasemin Dinc, Emel Oguz Akarsu, Sarra Elhamida Lazrak, Sanja Gluscevic, Abdulkadir Tunc, Meral Seferoglu, Caner Baydar, Ali Ozhan Sıvacı, O. Faruk Turan, Guven Ozkaya

Secondary hypogammaglobulinemia and lymphocytopenia in patients with inflammatory neurological diseases on anti-CD20 therapy: risk of infection and infection-related mortality

Bedriye Karaman, Göktuğ Dinçer, Rasim Tunçel, Ozgul Ekmekci, Nur Yüceyar

Risk factors for poor response to initial first-line immunotherapy and subsequent immunotherapy on prognosis in pediatric anti-NMDA receptor encephalitis

Yuhang Li, Hanyu Luo, Zhiwei Yu, Jiaxin Yang, Yan Jiang, Xiujuan Li, Jiannan Ma, Li Jiang

Rare association of Tolosa-Hunt Syndrome with Sjogren’s Syndrome: case report and review of immunological links across autoimmune disorders”

  • DBS
  • Original Article

Hosna Elshony, Rakan Almuhanna, Rabia Muddassir

Frequency of anti-GQ1b IgG antibody in Miller Fisher syndrome: a Chinese single center study

Pengfei Shao, Wenhui Wu, Xin Zhang, Haifeng Chen, Yun Xu, Qing Ye

Delphi consensus finding on paediatric-adult transition: results from the epilepsy transition working group of the italian league against epilepsy (LICE)

F. Darra, P. Biermann Klaus, D. Audenino, F. Bisulli, A. Cossu, M. Elia, A. La Neve, M. Mancardi, C. Pastori, J. Proietti, F. Ragona, R. Rizzi, A. Rosati, V. Sciruicchio, N. Specchio, C. Stipa, C. Zanus, F. Villani

Case series of functional non epileptic seizures (PNES) in patients with brain tumors

Roni Loebenstein, Shany Guly Gofrit, Mailam Eltity, Erez Magiel, Uriel Fennig, Keren Altman, Ory Haisraely, Noga Atar, Elisheva Jan, Naum Margolin, Marina Boxer, Nicola Maggio, Alisa Taliansky

TMS-Indexed neurophysiological signatures of neural compensation in spinal cord injury: associations with injury level, motor function, and affective modulation

Guilherme J. M. Lacerda, Luis Fernando Gonzalez-Gonzalez, Kevin Pacheco-Barrios, Linamara R. Battistella, Felipe Fregni

Describing phenotypes in FSHD: an update of the comprehensive clinical evaluation form

Giulia Ricci, Francesca Torri, Lucia Ruggiero, Liliana Vercelli, Giulio Gadaleta, Enrica Rolle, Barbara Risi, Elena Carraro, Teresinha Evangelista, Enrico Bugiardini, Nicolas Dubuisson, Nicol Voermans, Gabriele Siciliano, Tiziana Mongini, Massimiliano Filosto, Isabella Allegri, Andrea Barp, Roberta Battini, Angela Berardinelli, Michela Coccia, Giacomo Comi, Maurizio Moggio, Monica Sciacco, Maria Grazia D’Angelo, Eleonora Diella, Giovanni Di Muzio, Chiara Fiorillo, Davide Gabellini, Matteo Garibaldi, Giovanni Antonini, Emiliano Giardina, Claudia Strafella, Luca Colantoni, Marina Grandis, Maurizio Inghilleri, Rocco Liguori, Maria Lucia Valentino, Lorenzo Maggi, Isabella Moroni, Roberto Massa, Sabrina Mata’, Vincenzo Nigro, Elena Pegoraro, Corrado Angelini, Antonio Petrucci, Luisa Politano, Stefano Previtali, Alessandra Renieri, Enzo Ricci, Mauro Monforte, Carmelo Rodolico, Cristina Sancricca, Valeria Ada Sansone, Lucio Santoro, Antonio Trabacca, Mara Turri, Rossella Tupler, Gaetano Vattemi, Paola Tonin, Lorenzo Verriello

Long term clinical follow-up and natural history in a cohort of Italian patients with GNE myopathy: the experience of a single centre

Alessia Pugliese, M. Sframeli, P. D’Ambrosio, A. Barbaccia, F. Biasini, A. Migliorato, C. Terranova, S. Messina, A. Toscano, C. Rodolico

The effect of Gua Sha therapy on Parkinson's disease with rapid eye movement sleep behavior disorder: a randomized controlled trial

Mengyuan Chen, Jie Liu, Haotian Ge, Xinyue Zhang, Ying Zhu, Zichun Ding, Juping Chen, Qiuqin Wang, Guihua Xu

Rapidly progressive dementia in tacrolimus neurotoxicity: rare but reversible

Siddharth Chand, Riya Sharma, Alaipreet Kaur, Saurabh Mishra, Victo Varghese, Manoj Kumar, Raza A. Mahdi, Manoj K. Goyal, Ritu Shree

Intracranial vertebral artery dissection without hemorrhagic presentation

Marialuisa Zedde, Rosario Pascarella

Misdiagnosis of autoimmune glial fibrillary acidic protein astrocytopathy as infectious meningitis: a case report

Chengji Wu, Xuefei Han, Fen Yang, Guangyun Zhang, Cong Zhao

Baxter’s nerve: the hidden culprit of chronic heel pain

Roberto Tedeschi

Delayed diagnosis of myasthenia gravis caused by concurrent anxiety symptoms

Valentina Gasparini, Daniele Mattavelli, Leonardo Pantoni

From clinic to stage: Jean-Martin Charcot’s influence on the performing arts (Cinema, Theatre, Dance, and Opera)

  • History of Neurology

Francesco Brigo

COVID-19 postmortem neuropathology: insights of a meta-analysis of 464 cases

David S. Younger

A new instrument for the assessment of laterality: evidence from confirmatory analysis

  • Letter to the Editor

Muhammad Bari Hassan, Danish Kumar Goswami, Barkha Goswami, FNU Neelam, Zainab Obaidullah, Ali Karim

A reply to the letter to the editor by Bari Hassan and colleagues

  • Letter to the Editor

Mirko Duradoni, Andrea Frosini, Giorgio Gronchi, Andrea Peru

Serum sirtuin 3 levels and multimodal abnormalities in brain structure and function in Parkinson’s disease patients with depression

Mahnoor Sultana, Ayesha Parvaiz Malik, Javed Iqbal, Brijesh Sathian

Letter to the Editor: comment on article ‘Fear of falling impairs spatiotemporal gait parameters, mobility, and quality of life in Parkinson’s disease: a cross-sectional study’

Bradley Lonergan, Benjamin H. L. Harris, Vincent E. S. Allott, Michael B. Fertleman, Louis J. Koizia

Letter to the Editor regarding “The effects of transcranial magnetic stimulation in motor symptoms of Parkinson’s disease: an overview of systematic reviews with meta-analysis”

Ehsan Alimohammadi

Compound heterozygous mutations in the SYNE1 gene causing atypical juvenile motor neuron disease

Federica Ginanneschi, Francesca Mari, Nila Volpi, Giulia Maccanti, Stefania Casali

Wilson disease: time frame for improvement of neurological symptomology may exceed a decade

Vinisha Somaya, Marketa Hušáková, Radan Brůha, Petr Dušek

Stroke accompanied by diffuse salt-and-pepper skin changes: anticoagulation or anti-inflammatory therapy?

Liu Huiyi, Liu Yang

Carotid reconstitution in chronic dissection

Marialuisa Zedde, Daniele G. Romano, Luca Valvassori, Rosario Pascarella

Andexanet alfa in patients with spontaneous intracerebral hemorrhage related to apixaban or rivaroxaban

Manuel Cappellari, Andrea Zini, Danilo Toni

Artery of percheron infarction presented as encephalitis-like manifestations

Chen Ye, Youjie Wang, Biqiu Tang, Ruosu Pan, Bo Wu

Severe hypomagnesemia mimicking acute stroke: a rare but overlooked mimic?

Angelo Pascarella, Roberta Cutellè, Vittoria Cianci, Sara Gasparini, Edoardo Ferlazzo

Buccal neuralgia: a potential cause of facial pain

María-Luz Cuadrado, Farzin Falahat, Nuria González-García, José A. Arias-Navalón

Key factors influencing outcomes in children with severe traumatic brain injury

Kousar Ahmadi, Ehsan Alimohammadi

Unraveling X-linked adrenoleukodystrophy in women: a rare case of central nervous system manifestations and implications for screening

Chiara Esposto, Pietro Iaffaldano

Diaphragm ultrasound and neostigmine test as complementary tools in the diagnostic assessment of myasthenia gravis: insights from a clinical case

Zhuangzhuang Zhang, Xiaoying Lv, Yiming Zheng, Qing Yu, Xiaohui Zhang, Ran Liu, Yun Yuan, Hongjun Hao, Feng Gao

Brainstem and optic pathway involvement in wolfram syndrome

Laura Manuela Olarte Bermúdez, Ana M. Rendón-Garavito, Oscar Torres

Pseudoaneurysm of the middle meningeal artery as a delayed complication of head trauma

Nicola Romano, Annapaola Truono, Antonio Castaldi

The “H sign” in MOGAD myelitis

Santiago Aristizabal Ortiz, Laura Andrea Campaña Perilla, Angela Patricia Guarnizo Capera

Generalized cortical encephalitis in autoimmune GFAP astrocytopathy

Yu Guo, Hongjun Hao, Yunchuang Sun

Palatal tremor as the clue sign of POLG-related syndrome

Sara Satolli, Andrea Mignarri, Filippo Maria Santorelli

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Case challenge: neuroimaging in Alzheimer disease (Link opens in a new window)

Put your decision-making and interpretation skills into practice with these six cases focusing on different presentations. Can you choose the optimal PET tracer, accurately interpret the results, and advise on next steps?

This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Lilly
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Navigating neuroimaging in Alzheimer’s care: Practical applications and strategies for integration/© Springer Health+ IME