09-05-2024 | Neuroendocrine Tumor | ASO Author Reflections
ASO Author Reflections: Radio-Guided Surgery in Small Intestine Neuroendocrine Tumors: New Probe, New Perspectives?
Authors:
Emilio Bertani, MD, Francesco Mattana, MD, Francesco Collamati, PhD, Mahila E. Ferrari, MSc, Vincenzo Bagnardi, PhD, Samuele Frassoni, MSc, Eleonora Pisa, MD, Riccardo Mirabelli, PhD, Silvio Morganti, MSc, Maria Danieli, MD, Nicola Fazio, MD, Uberto Fumagalli Romario, MD, Francesco Ceci, MD
Published in:
Annals of Surgical Oncology
|
Issue 7/2024
Login to get access
Excerpt
In recent decades, various studies have delved into the realm of radioguided surgery (RGS) employing gamma probes for neuroendocrine tumors (NET).
1,2 Despite its allure, the widespread clinical adoption of this approach has been hampered. This is partly due to the limitations of gamma probes in accurately distinguishing radioactive signals emitted from malignant tissue versus those originating from distant organs with physiological radiopharmaceutical uptake. However, a novel beta
+ probe has shown promise in addressing these limitations, as shown by a recent ex vivo study.
3 …