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Neurocritical Care

Issue 2/2025

Content (47 Articles)

Caring for Coma after Severe Brain Injury: Clinical Practices and Challenges to Improve Outcomes: An Initiative by the Curing Coma Campaign

Brooke Murtaugh, DaiWai M. Olson, Neeraj Badjatia, Ariane Lewis, Venkatesh Aiyagari, Kartavya Sharma, Claire J. Creutzfeldt, Guido J. Falcone, Amy Shapiro-Rosenbaum, Elizabeth K. Zink, Jose I. Suarez, Gisele Sampaio Silva, Sachin Agarwal, Venkatesh Aiyagari, Yama Akbari, Fawaz Al-Mufti, Asher Albertson, Sheila Alexander, Anne Alexandrov, Ayham Alkhachroum, Moshagan Amiri, Brian Appavu, Hugo Ardaillon, Charlene Aubinet, Meron Awraris Gebrewold, Marc Ayounb, Rafael Badenes, Mary Kay Bader, Neeraj Badjiata, Ram Balu, Brooke Barlow, Megan Barra, Rachel Beekman, Ettore Beghi, Andreas Bender, Erta Beqiri, Tracey Berlin, Federico Bilotta, Thomas Bleck, Yelena Bodien, Varina Boerwinkle, Melanie Boly, Alexandra Bonnel, Luca Brazzi, Emery Brown, Sebina Bulic, Eder Caceres, Adrian Caceres, Tullio Cafiero, Elizabeth Carroll, Emilio G. Cediel, Sherry Chou, Giuseppe Citerio, Jan Claassen, Chad Condie, Alfredo Conti, Katie Cosmas, Paolo Costa, Claire Creutzfeldt, Neha Dangayach, Mario Dauri, Derek Debicki, Michael DeGeorgia, Caroline Der-Nigoghossian, Masoom Desai, Rajat Dhar, Michael Diringer, Karin Diseren, Emily Durr, Brian Edlow, Ari Ercole, Anna Estraneo, Guido Falcone, Salia Farrokh, Adam Ferguson, Davinia Fernandez-Espejo, Ericka Fink, Joseph Fins, Brandon Foreman, Federico Franchi, Jennifer Frontera, Rishi Ganesan, Nicolas Gaspard, Ahmeneh Ghavam, Joseph Giacino, Christie Gibbons, Emily Gilmore, Chavie Glustein, Olivia Gosseries, Theresa Green, David Greer, Mary Guanci, Deepak Gupta, Cecil Hahn, Ryan Hakimi, Flora Hammond, Daniel F. Hanley, Ahmed Hassan, Raimund Helbok, Claude Hemphill, Arthur Henrique Galvão Bruno Da Cunha, H. E. Hinson, Karen Hirsch, Sarah Hocker, Peter Hu, Xiao Hu, Theresa Human, David Hwang, Judy Illes, Matthew Jaffa, Michael L. James, Anna Janas, Susan Johnson, Jane Johr, Morgan Jones, Ralf J. Jox, Atul Kalanuria, Emanuela Keller, Lori Kennedy, Megan Kennelly, Maggie Keogh, Jenn Kim, Keri Kim, Hannah Kirsch, Matthew Kirschen, Nerissa Ko, Daniel Kondziella, Natalie Kreitzer, Julie Kromm, Abhay Kumar, Pedro Kurtz, Steven Laureys, Thomas Lawson, Nicolas Lejeune, Ariane Lewis, John Liang, Geoffrey Ling, Sarah Livesay, Jacques Luaute, Andrea Luppi, Jennifer MacDonald, Craig Maddux, Dea Mahanes, Sherif Mahmoud, Shraddha Mainali, Nelson Maldonado, Rennan Martins Ribeiro, Luciana Mascia, Errikos Maslias, Marcello Massimini, Rohan Mathur, Stephan Mayer, Victoria McCredie, Molly McNett, Jorge Mejia-Mantilla, Michael Mendoza, David Menon, Geert Meyfroidt, Julio Mijangos, Dick Moberg, Asma Moheet, Erika Molteni, Elisa Montalenti, Martin Monti, Chris Morrison, Susanne Muehlschlegel, Marina Munar, Brooke Murtaugh, Lionel Naccache, Masao Nagayama, Emerson Nairon, Thomas Nakagawa, Andrea Naldi, Ganesalingam Narenthiran, Girija Natarajan, Esther Nemetsky, Virginia Newcombe, Niklas Nielsen, Naomi Niznick, Filipa Noronha-Falcão, Paul Nyquist, Katherine O’Brien, DaiWai Olson, Marwan Othman, Berno Overbeek, Adrian Owen, Llewellyn Padayachy, Mehrnaz Pajoumand, Soojin Park, Lindsey Patton, Melissa Pergakis, Heidi Perry, Len Polizzotto, Nader Pouratian, Marilyn Price Spivack, Lara Prisco, Javier Provencio, Francesco Puglises, Louis Puybasset, Chethan Rao, Lindsay Rasmussen, Verena Rass, Frank Rasulo, Bappaditya Ray, Michael Reznik, Zaccaria Ricci, Risa Richardson, Cassia Righy Shinotsuka, Chiara Robba, Courtney Robertson, Benjamin Rohaut, John Rolston, Stefano Romagnoli, Mario Rosanova, Eric Rosenthal, Shaun Rowe, Michael Rubin, Mary Beth Russell, Gisele Sampaio Silva, Leandro Sanz, Simone Sarasso, Aarti Sarwal, Nicolas Schiff, Caroline Schnakers, David Seder, Vishank Arun Shah, Amy Shapiro-Rosenbaum, Angela Shapshak, Kartavya Sharma, Kumar Ajay Sharma, Tarek Sharshar, Lori Shutter, Jacobo Sitt, Beth Slomine, Keaton Smetana, Peter Smielewski, Wade Smith, Beth Solomine, Emmanuel Stamatakis, Alexis Steinberg, Robert Stevens, Jose Suarez, Gene Sung, Bethany Sussman, Shaurya Taran, Anna Teresa Mazzeo, Aurore Thibaut, David Thompson, Zachary Threlkeld, Lorenzo Tinti, Daniel Toker, Michel Torbey, Jenna Tosto, Stephen Trevick, Georgia Tsaousi, Alexis Turgeon, Lynne Turner Stokes, Andrew Udy, Panos Varelas, Paul Vespa, Walter Videtta, Henning Voss, Ford Vox, Michaela Waak, Amy Wagner, Sarah Wahlster, Mark Wainwright, Jennifer Weaver, John Whyte, Briana Witherspoon, Aleksandra (Sasha) Yakhkind, Susan Yeager, Michael Young, Sahar Zafar, Ross Zafonte, Darin Zahuranec, Chris Zammit, Bei Zhang, Wendy Ziai, Lara Zimmerman, Elizabeth Zink

Nimodipine in Aneurysmal Subarachnoid Hemorrhage: Are Old Data Enough to Justify Its Current Treatment Regimen?

Juan Antonio Llompart-Pou, Jon Pérez-Bárcena, Daniel Agustín Godoy

Intrathecal Nicardipine—Time to Treat the Symptom?

Ofer Sadan, Feras Akbik

Liberalization of the Systemic Glucose Management is Associated with a Reduced Frequency of Neuroglucopenia in Subarachnoid Hemorrhage Patients: An Observational Cohort Study

Mario Kofler, Anna Lindner, Verena Rass, Bogdan A. Ianosi, Lauma Putnina, Philipp Kindl, Alois J. Schiefecker, Maxime Gaasch, Ronny Beer, Paul Rhomberg, Claudius Thomé, Erich Schmutzhard, Bettina Pfausler, Raimund Helbok

Elevated Blood Pressure and Culprit Aneurysm Rebleeding During the Unsecured Period of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review

Luke A. Terrett, Jessica Reszel, Sara Ameri, Alexis F. Turgeon, Lauralyn McIntyre, Shane W. English

Contribution of an Automatic Algorithm for Quantifying the Volume of Aneurysmal Subarachnoid Hemorrhage to the Evaluation of the Risk of Occurrence of Delayed Cerebral Ischemia: A Cohort Study

Pierre Simeone, Thomas Corrias, Nicolas Bruder, Salah Boussen, Dan Cardoso, Audrey Alonzo, Anthony Reyre, Hervé Brunel, Nadine Girard, Thomas Graillon, Henry Dufour, David Couret, Lionel Velly

Comparative Efficacy and Safety of External Ventricular Drains and Intraparenchymal Pressure Monitors for Intracranial Pressure Monitoring in Traumatic Brain Injury: A Systematic Review and Meta-analysis

Luis A. Marin-Castañeda, Rolando A. Gómez-Villarroel, Geronimo Pacheco Aispuro, Nadia Palomera-Garfias, Niels Pacheco-Barrios, Valery M. Sandoval-Orellana, Pavel S. Pichardo-Rojas

Machine Learning Based Prediction of Imminent ICP Insults During Neurocritical Care of Traumatic Brain Injury

Peter Galos, Ludvig Hult, Dave Zachariah, Anders Lewén, Anders Hånell, Timothy Howells, Thomas B. Schön, Per Enblad

The Pupillary Light-Off Reflex in Acute Disorders of Consciousness

  • Open Access
  • Coma
  • Original work

Pardis Zarifkar, Marwan H. Othman, Karen Irgens Tanderup Hansen, Moshgan Amiri, Sarah Gharabaghi Stückler, Maria Louise Fabritius, Sigurdur Thor Sigurdsson, Christian Hassager, Peter F. Birkeland, John Hauerberg, Kirsten Møller, Jesper Kjaergaard, Merlin D. Larson, Daniel Kondziella

Comparison of Risk Factors for Early Seizures Between Angiogram-Negative and Aneurysmal Subarachnoid Hemorrhage

Ariyaporn Haripottawekul, Ava Stipanovich, Karen L. Furie, Michael E. Reznik, Ali Mahta

Semiautomated Hemorrhage Volume Quantification in Aneurysmal Subarachnoid Hemorrhage

Sebastian Sanchez, Jacob M. Miller, Matthew T. Jones, Rishi R. Patel, Elena Sagues, Carlos Dier, Andres Gudino, Navami Shenoy, Ariel Vargas-Sanchez, Edgar A. Samaniego

Alterations in Regional Brain Microcirculation in Patients with Sepsis: A Prospective Study Using Contrast-Enhanced Brain Ultrasound

Duc Nam Nguyen, Luc Huyghens, Truc Mai Nguyen, Marc Diltoer, Joop Jonckheer, Wilfried Cools, Lotte Segers, Johan Schiettecatte, Jean-Louis Vincent

Lower Perceived Social Support During Hospitalization by Close Family Members may have Significant Associations with Psychological Distress 1 Month After Cardiac Arrest

Mina Yuan, Isabella M. Tincher, Danielle A. Rojas, Bhanvi Sachdeva, Sabine Abukhadra, Christine E. DeForge, Kristin Flanary, Bernard P. Chang, Sachin Agarwal

Predictive Hypoxemic Threshold for Tolerating the Apnea Test While Assessing Death by Neurological Criteria

Daniel Aviram, Daniel Hikri, Michal Aharon, Amir Galoz, Yael Lichter, Noam Goder, Asaph Nini, Nimrod Adi, Dekel Stavi

Robotic Assisted Transcranial Doppler Monitoring in Acute Neurovascular Care: A Feasibility and Safety Study

  • ECMO
  • Original work

Alvise Fattorello Salimbeni, Caterina Kulyk, Francesco Favruzzo, Ludovica De Rosa, Federica Viaro, Alessio Pieroni, Stefano Mozzetta, Milan R. Vosko, Claudio Baracchini

Noninvasive Method Using Mechanical Extensometer for the Estimation of Intracranial Compliance by Repeated Measures Agreement Analysis

Sanem Pinar Uysal, Hayley G. Williams, Mina Huerta, Nicolas R. Thompson, Catherine E. Hassett

A Survey on the Management of Patients with Severe Traumatic Brain Injury During Pregnancy: The MAMA Study

Edoardo Picetti, Monica S. Vavilala, Raul Coimbra, Rafael Badenes, Marta V. Antonini, Goran Augustin, Rocco Armonda, Walter L. Biffl, Simone Di Filippo, Daniel A. Godoy, Brian Gordon, Matthew J. Martin, Kevin G. Phung, Fabio S. Taccone, Gianluigi Zona, Fausto Catena, Chiara Robba

Development of a Quality Indicator Set for the Optimal Acute Management of Moderate to Severe Traumatic Brain Injury in the Australian Context

Toby Jeffcote, Camila R. Battistuzzo, Rebecca Roach, Catherine Bell, Cino Bendinelli, Stephen Rashford, Ron Jithoo, Belinda J. Gabbe, Oliver Flower, Gerard O’Reilly, Lewis T. Campbell, D. James Cooper, Zsolt J. Balogh, Andrew A. Udy, Andrew Chow, Anthony Delaney, Andrew Hooper, Aniket Nadkarni, Amber-Louise J. Poulter, Adam Wells, Benjamin Reddi, Biswadev Mitra, Brad Sheridan, Brian Burns, Carly Rienecker, Daniel Bodnar, David Bowen, Dashiell Gantner, Fatima Nasrallah, Geoffrey Healy, Gleen Ryan, James R. Anstey, Jeremy Hsu, Judith Bellapart, Kate King, Kelly Harbour, Rosalind L. Jeffree, Shailesh Bihari, Melinda Fitzgerald, Michael Noonan, Mark Plummer, Michael C. Reade, Michaela Waak, Mark Weeden, Paul David Cooper, Peter Cameron, Rinaldo Bellomo, Robert McNamara, Stephen McGloughlin, Terence J. O’Brien, Teresa Withers, Torg Westerlund

Factors Related to Nonachievement of Intensive Blood Pressure–Lowering Target in Patients with Intracerebral Hemorrhage

Daniel Vázquez-Justes, Miriam Paul-Arias

Effectiveness of Fosphenytoin and Levetiracetam to Prevent Posttraumatic Seizures in Young Children with Accidental or Abusive Traumatic Brain Injury

Caitlin R. McNamara, Cesar I. Menchaca, Taylor J. Abel, Christopher M. Horvat, Rachel P. Berger, Ericka L. Fink, Patrick M. Kochanek, Dennis W. Simon

Feasibility Study of Endoscopic Surgery for Spontaneous Intracerebral Hemorrhage with Large Hematoma: a Comparison with Craniotomy Using Propensity Score Matching Analysis

Min Cui, XiaoYong Tang, WeiMing Xiong, YongBing Deng, Qiang Yang

Oxygen-Based Autoregulation Indices Associated with Clinical Outcomes and Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage

Andrew P. Carlson, Thomas Jones, Yiliang Zhu, Masoom Desai, Ali Alsarah, C. William Shuttleworth

Effects of Argon in the Acute Phase of Subarachnoid Hemorrhage in an Endovascular Perforation Model in Rats

Harald Krenzlin, Dominik M. A. Wesp, Anika A. E. Korinek, Henning Ubbens, Jakob Volland, Julia Masomi-Bornwasser, Katharina J. Weber, Dominik Mole, Clemens Sommer, Florian Ringel, Beat Alessandri, Naureen Keric

Quantitative and Radiological Assessment of Post-cardiac-Arrest Comatose Patients with Diffusion-Weighted Magnetic Resonance Imaging

Sam Van Roy, Liangge Hsu, Joseph Ho, Benjamin M. Scirica, David Fischer, Samuel B. Snider, Jong Woo Lee

Sedation Intensity in Patients with Moderate to Severe Traumatic Brain Injury in the Intensive Care Unit: A TRACK-TBI Cohort Study

Rianne G. F. Dolmans, Jason Barber, Brandon Foreman, Nancy R. Temkin, David O. Okonkwo, Claudia S. Robertson, Geoffrey T. Manley, Eric S. Rosenthal

Seizure Characteristics and EEG Features in Intoxication Type and Energy Deficiency Neurometabolic Disorders in the Pediatric Intensive Care Unit: Single-Center Experience Over 10 Years

Kuntal Sen, Dana Harrar, Nicole Pariseau, Karis Tucker, Julia Keenan, Anqing Zhang, Andrea Gropman

Predictive Models of Long-Term Outcome in Patients with Moderate to Severe Traumatic Brain Injury are Biased Toward Mortality Prediction

Florian P. Martin, Thomas Goronflot, Jean D. Moyer, Olivier Huet, Karim Asehnoune, Raphaël Cinotti, Pierre A. Gourraud, Antoine Roquilly

Impact of Aphasia on Brain Activation to Motor Commands in Patients with Acute Intracerebral Hemorrhage

Samuel D. Jacobson, Vedant Kansara, Stephanie Assuras, Qi Shen, Lucie Kruger, Jerina Carmona, You Lim Song, Lizbeth Cespedes, Mariam Yazdi, Angela Velazquez, Ian Gonzales, Satoshi Egawa, E. Sander Connolly, Shivani Ghoshal, David Roh, Sachin Agarwal, Soojin Park, Jan Claassen

Intrathecal Nicardipine After Aneurysmal Subarachnoid Hemorrhage: A Scoping Review

Jared F. Sweeney, John Chen, Bassem Darwish, Devin Holden, Erin Barnes, Panayiotis Varelas

Ketamine for Critically Ill Patients with Severe Acute Brain Injury: A Systematic Review with Meta-analysis and Trial Sequential Analysis of Randomized Clinical Trials

Trine Hjorslev Andreasen, Frederik Andreas Madsen, Marija Barbateskovic, Jane Lindschou, Christian Gluud, Kirsten Møller

Efficacy of N-Methyl-D-Aspartate (NMDA) Receptor Antagonists in Treating Traumatic Brain Injury–Induced Brain Edema: A Systematic Review and Meta-analysis of Animal Studies

Fernanda Cristina Poscai Ribeiro, Nadine Vieira de Oliveira, Gabriela Regonha Coral, Alcântara Ramos de Assis César, Moisés Willian Aparecido Gonçalves, Erika Said Abu Egal, Kleber Fernando Pereira

Decompressive Craniectomy with or Without Dural Closure: Systematic Review and Meta-analysis

Henrique L. Lepine, Gabriel Semione, Raphael G. Povoa, Gustavo de Oliveira Almeida, David Abraham, Eberval G. Figueiredo

Shared Decision-Making for Patients with Stroke in Neurocritical Care: A Qualitative Meta-Synthesis

Hui Zhang, Carmel Davies, Diarmuid Stokes, Deirdre O’Donnell

The Impact of Sedative Choice in the Management of Aneurysmal Subarachnoid Hemorrhage: A Scoping Review

James Then, Samuel Tawfik, Timothy Law, Alastair Brown, Vanessa Carnegie, Andrew Udy, Toby Jeffcote

Cyclooxygenase 2 Inhibitors for Headache After Elective Cranial Neurosurgery: Results from a Systematic Review of Efficacy of Cyclooxygenase 2 Inhibitors for Headache After Acute Brain Injury

Hector David Meza Comparan, Anum Khaliq, Luciola Martins Frota, Daniela Pomar-Forero, Bakhtawar Ahmad, Erica Marnet, Fernanda J. P. Teixeira, Anita Thomas, Priyank Patel, Haley Brunkal, Saanvi Singireddy, Brandon Lucke-Wold, Carolina B. Maciel, Katharina M. Busl

Peer-Delivered Interventions for Caregivers in the ICU with a Focus on Severe Acute Brain Injury: A Scoping Review

Mira Reichman, Victoria A. Grunberg, Alexander M. Presciutti, Katherine T. Foster, Ana-Maria Vranceanu, Claire J. Creutzfeldt

Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis

Khalid Sarhan, Rashad G. Mohamed, Reem Reda Elmahdi, Youstina Mohsen, Asmaa Elsayed, Dania Mosaad Zayed, Menna A. Elkholi, Nagat Gabr, Enjy M. El-Bialy, Ibrahim Serag

Which Intravenous Isotonic Fluid Offers Better Outcomes for Patients with a Brain Injury?

Akshitkumar M. Mistry

Futurology: What Would Future Historians of Neurocritical Care Write About?

  • Neurocritical Care Through History

Eelco F. M. Wijdicks

A Case of Guillain–Barré Syndrome and Repurposing cEEG to Enable Communication in Total Locked-in Syndrome

Thomas J. Pisano, Joshua M. Levine

Brain Ultrasound for External Ventricular Drain Catheter Localization and Intrathecal Antibiotic Administration: Overcoming Transport Challenges

Gabriel Machado Naus dos Santos, Marcus Arthur Pereira, Fernanda Alves, Juliana Caldas

Missing Elements that Can Possibly Influence Manual and Robotic-Assisted Transcranial Doppler Monitoring

Indu Kapoor, Hemanshu Prabhakar, Charu Mahajan

Authors’ Response: Robotic Assisted Transcranial Doppler Monitoring in Acute Neurovascular Care: A Feasibility and Safety Study

Alvise Fattorello Salimbeni, Ludovica De Rosa, Claudio Baracchini

Commentary on “Efficacy of N-Methyl-D-Aspartate (NMDA) Receptor Antagonists in Treating Traumatic Brain Injury–Induced Brain Edema: A Systematic Review and Meta-Analysis of Animal Studies”

Ankur Kapoor, Rachana Mehta, Muhammed Shabil, Sanjit Sah

Reply to the Comment on “Efficacy of N-Methyl-D-Aspartate (NMDA) Receptor Antagonists in Treating Traumatic Brain Injury–Induced Brain Edema: A Systematic Review and Meta-Analysis of Animal Studies”

Fernanda Cristina Poscai Ribeiro, Nadine Vieira de Oliveira, Gabriela Regonha Coral, Alcântara Ramos de Assis César, Moisés Willian Aparecido Gonçalves, Erika Said Abu Egal, Kleber Fernando Pereira

Modifying the Apnea Test to Minimize Complications

  • Letters to the editor

Summit Dev Bloria

Proceedings of the Sixth Regional Neurocritical Care Meeting in the Middle East and Africa in Conjunction with the Kuwait 12th Critical Care Conference

Feb 25
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Jun 25
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