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Neurocritical Care

Issue 1/2026

Content (45 Articles)

Commentary: Invasive and Noninvasive Intracranial Pressure Pulse Waveform in Neurocritical Care Patients with Different Cranium Integrity

Shraddha Mainali

Is it Time to Upgrade Neuromonitoring in ECPR Recipients to Evaluate Cerebral Perfusion Imbalances Adequately?

Alberto Marabotti, Giovanni Cianchi, Andrea Franci, Manuela Bonizzoli

Transfusion in Surgical SAH: Between Guidelines, New Evidence, and Physiology

  • Viewpoint

Cyril Pernod, Hilaire de Malleray, Philippe Goutorbe

Effect of Ketamine Analgosedation on Neurological Outcome in patients with Severe Traumatic Brain Injury: A Randomized Controlled Pilot Study

Sourav Burman, Rajendra Singh Chouhan, Niraj Kumar, Charu Mahajan

Systolic Blood Pressure Reduction with Stability as a New Therapeutic Goal in Patients with Intracerebral Hemorrhage: Results of the Pooled Analysis of ATACH 2 and INTERACT 2 Trials

Adnan I. Qureshi, William Baskett, Renee H. Martin, Pashmeen Lakhani, Ibrahim A. Bhatti, Hijrah El Sabae, Fawaz Al-Mufti, Joao A. Gomes, Ali Seifi, Alejandro A. Rabinstein, Jose I. Suarez, Thorsten Steiner, Chi-Ren Shyu, Craig S. Anderson

Traumatic Venous Sinus Thrombosis: Patient and Practice Patterns at a Major Trauma Center

Deborah L. Huang, Ritwik Bhatia, Rubinee Simmasalam, Jason F. Talbott, Michael C. Huang, Vineeta Singh

The Cognitive Status Scale: A Preliminary Investigation of Psychometric Properties in a Clinically Referred Pediatric Critical Care Sample

  • Original work

Trevor A. Hall, Susanne W. Duvall, Lauren Demers, Natalia Rich-Wimmer, Cydni N. Williams

Paroxysmal Cortical Slowing Predicts Posttraumatic Epilepsy After Severe Traumatic Brain Injury

Yonatan Serlin, Hamza Imtiaz, Mark A. Maclean, Matthew W. Pease, David O. Okonkwo, Ava M. Puccio, Shawn Eagle, James F. Castellano, Sara K. Inati, Alon Friedman

An Exploratory Analysis of Chemical and Mechanical VTE Prophylaxis in Patients with High Rebleeding Risk Traumatic Brain Injury

Heather X. Rhodes-Lyons, Adel Elkbuli, Sanjan Kumar, Nikita Nunes Espat, Sarah E. Johnson, David L. McClure, Antonio Pepe

Hemoglobin and Perihematomal Edema After Intracerebral Hemorrhage: A Post Hoc Analysis of the i-DEF Trial

Alexandros A. Polymeris, Vasileios-Arsenios Lioutas, Sarah Marchina, David J. Seiffge, David J. Roh, Fernanda Carvalho Poyraz, Magdy H. Selim

Hypothermia Alleviates TBI-Induced Tau Hyperphosphorylation Through RBM3-Dependent GSK-3β and AMPK Pathways

Bingjin Liu, Qunfang Zhao, Qingqing Shi, Weiqi Xu, Fangxiao Shi, Ruhui Yang, Xinwen Zhou

KidsBrainIT: Visualization of the Impact of Cerebral Perfusion Pressure Insult Intensity and Duration on Childhood Brain Trauma Outcome

Bavo Kempen, Bart Depreitere, Ian Piper, Maria Poca, Stefan Mircea Iencean, Mireia Garcia, James Weitz, Gayathri Subramanian, Roddy O’Kane, Julian Zipfel, Arta Barzdina, Stefano Pezzato, Patricia A. Jones, Tsz-Yan Milly Lo

Characterizing Stressors and Coping Strategies Among Caregivers of Patients with Severe Acute Brain Injury by Level of Distress

Katherine J. Meurer, Alexander M. Presciutti, Sarah M. Bannon, Rina Kubota, Nithyashri Baskaran, Jisoo Kim, Qiang Zhang, Mira Reichman, Nathan S. Fishbein, Kaitlyn Lichstein, Melissa Motta, Susanne Muehlschlegel, Michael E. Reznik, Matthew N. Jaffa, Claire J. Creutzfeldt, Corey R. Fehnel, Amanda D. Tomlinson, Craig A. Williamson, Ana-Maria Vranceanu, David Y. Hwang

Ability of a Composite Brain Magnetic Resonance Imaging Score to Predict Neurologic Outcomes in Survivors of Out-Of-Hospital Cardiac Arrest

Thuhien Nguyen, Nicolas Poilvert, Victor Lin, Hope Opara, Nassim Matin, Arielle P. Davis, Breana L. Taylor, Catherine R. Counts, Penelope Chung Thomas, Monisha Sharma, James A. Town, Sarah Wahlster, Nicholas J. Johnson

A Machine Learning Model to Predict Treatment Effect Associated with Targeted Temperature Management After Cardiac Arrest

Jocelyn Hsu, Han Kim, Kirby Gong, Carl Harris, Tej D. Azad, Robert D. Stevens

Near-Infrared Spectroscopy to Assess Covert Volitional Brain Activity in Intensive Care

  • Open Access
  • Coma
  • Original work

Pardis Zarifkar, Matthew Kolisnyk, Marwan H. Othman, Melika Hassani, Karen Irgens Tanderup Hansen, Morten Hylander Møller, Kirsten Møller, Christine Sølling, Jens Christian Nilsson, Sigurdur Thor Sigurdsson, Michael E. Benros, Jack de Jeu, Karnig Kazazian, John Hauerberg, Kåre Fugleholm, Peter F. Birkeland, Tobias S. Andersen, Jesper Kjaergaard, Daniel Kondziella

Impact of Low-Dose Ketamine Infusion on Intracranial Pressure and Hemodynamics in Septic Shock Patients

Essamedin M. Negm, Hossam Tharwat Ali, Hanaa A. Nofal, Ahmed Mosallem, Ashraf Elsayed Ahmed, Ahmed Ali Morsy, Tamer S. Elserafy, Marwan Elgohary, Khaled Mohamed Altaher, Sherif Sharaf EL Deen, Hani A. Albialy, Ahmed M. Gouda, Ahmed Beniamen

In vivo Testing of the Pressio Intracranial Pressure Monitor

Laurent Gergelé, Jérémy Mallard, Clément Magand, Kevin Lagarde, Russel Chabanne, Jérôme Morel, Jean François Payen, Yoann Launey

Fast and Slow Recovery of Consciousness Following Traumatic Brain Injury

Sujith Swarna, Jordan R. Saadon, Jermaine Robertson, Vaibhav Vagal, Nathaniel A. Cleri, Kurt Butler, Xi Cheng, Yindong Hua, Seyed Morsal Mosallami Aghili, Chiemeka Uwakwe, Jason Zhang, Xuwen Zheng, Aniket Singh, Cassie Wang, Thomas Hagan, Chuan Huang, Petar M. Djurić, Charles B. Mikell, Sima Mofakham

Treatment, Diagnostic Approach, and Long-Term Outcomes of Lance-Adams Syndrome

Helena Xeros, Amra Sakusic, Jennifer E. Fugate, Maximiliano A. Hawkes, Eelco F. M. Wijdicks, Alejandro A. Rabinstein, Sherri A. Braksick

Development and Validation of Machine Learning Models for Predicting 7-Day Mortality in Critically Ill Patients with Traumatic Spinal Cord Injury: A Multicenter Retrospective Study

  • Original work

Yixi Wang, Xinkai Luo, Jingjie Wang, Wenzhe Li, Jian Cui, Yuqian Li

Impact of Hemorrhage Extent on External Ventricular Drain-Associated Infections in Aneurysmal Subarachnoid Hemorrhage

Florian Ebel, Emilia Westarp, Matteo Poretti, Matthias von Rotz, Simon Stohler, Raymond Chen, Raphael Guzman, Maja Weisser, Sarah Tschudin-Sutter, Luigi Mariani, Michel Roethlisberger

Volume of Aneurysmal Subarachnoid Hemorrhage and Cognitive Outcomes

Elena Sagues, Navami Shenoy, Alex Van Dam, Lidia Diaz, Andres Gudino, Carlos Dier, Domenica Cifuentes, Ruben Calle, Linder Wendt, Kathleen Dlouhy, Mario Zanaty, Santiago Ortega-Gutierrez, Natalia Garcia-Casares, Edgar A. Samaniego

Feasibility and Clinical Utility of Low-Field Magnetic Resonance Imaging in Critically Ill Children: An Experience from Pakistan

Kiran Hilal, Qalab Abbas, Aniqa Abdul Rasool, Sidra Khan, Shahiryar Khan, Haider Ali, Kumail Khandwala, Iraj Khan, Sana Saeed, Akber Madhwani, Imran Nisar, Fyezah Jehan

Vagus Nerve Stimulation Attenuates Cognitive Impairment in Traumatic Brain Injury via the mtDNA/cGAS-STING/NLRP3 Inflammasome Axis

Bingkai Ren, Junwei Kang, Xiaoyang Dong, Lianghua Huang, Xiao Wu, Yunliang Tang

Exploring the Upper Limits of Cerebral Perfusion Pressure in Pediatric Traumatic Brain Injury: A STARSHIP Analysis

Stefan Yu Bögli, Ihsane Olakorede, Claudia Ann Smith, Peter Hutchinson, Marek Czosnyka, Peter Smielewski, Shruti Agrawal

Altered Neurocritical Care Management of Patients with Severe Traumatic Brain Injury Following Changed Positions of the Zero-Reference Points for Intracranial and Arterial Pressure Measurement

Linus Réen, Hannes Wikström, Edward Visse, David Cederberg, Peter Siesjö, Niklas Marklund

Impact of Minimally Invasive Surgery on Midline Shift and Outcomes in Large Supratentorial Spontaneous Intracerebral Hemorrhage: Post Hoc Analysis of MISTIE III

Wendy C. Ziai, Anusha Yarava, Joshua B. Gruber, Yunke Li, Nathan Walborn, Nick Rizzutti, Meghan Hildreth, Issam Awad, Daniel F. Hanley

Clinical Features and Outcomes in Adult Patients with Autoimmune Encephalitis Requiring Intensive Care: A Retrospective Cohort Study

Lixia Qin, Kexin Chen, Yiwen Zhou, Wei Wang, Wei Lu, Hainan Zhang

Invasive and Noninvasive Intracranial Pressure Pulse Waveform in Neurocritical Care Patients with Different Cranium Integrity

Magdalena Kasprowicz, Agnieszka Kazimierska, Marta Hendler, Danilo Cardim, Zofia Czosnyka, Marek Czosnyka, Wellingson Paiva, Sergio Brasil

Clinical Applications of Point-of-Care and Diagnostic Transcranial Doppler in the Pediatric Acute Care Setting: A Scoping Review

Virginie Plante, Nicole O’Brien, Simon MacDonald, Laurence Tabone, Camille Jutras, Eric Dornoff, Catherine Boulet, Kerri LaRovere

Neuropalliative Care in the Emergency Department: Three Roles, One Goal

Kristopher A. Hendershot, Kei Ouchi

Restrictive vs. Liberal Transfusion Strategy in Critically Ill Patients with Acute Brain Injury: A Systematic Review and Meta-analysis

Amanda Boutrik, Udenilson Nunes da Silva Junior, Matheus de Medeiros Fernandes, Luís Otávio Nogueira, Douglas Dias e Silva, Dayany Leonel Boone

Echoes of Danger: Clot in Transit Causing Stroke and Pulmonary Embolism

Kevin R. Olsen, Ekkehard M. Kasper

Quantitative EEG Markers of Elevated Intracranial Pressure in a Case of Carcinomatous Meningitis

Cody L. Nathan, Diamond A. Dominguez, Elizabeth Gerard

Corroborating the Monro–Kellie Principles

Eelco F. M. Wijdicks

Response to Commentary by Dr. Ofer Sadan and Dr. Feras Akbik

  • Letter To The Editor

Cappi Lay, Hae Young Baang

Re: Response to Commentary

Ofer Sadan, Feras Akbik

Ongoing Debate on IV Milrinone for Cerebral Vasospasm: “It Ain’t Over ‘Til It’s Over”

Karim Lakhal, Sigismond Lasocki

Response to Commentary by Dr. Lakhal and Dr. Lasocki

Cappi Lay, Hae Young Baang

Blood Pressure Variability Targets in Stroke Care: The Need for Prospective Validation Before Clinical Implementation

  • Stroke
  • Letters to the editor

Arnaldo Alves da Silva, Rogerio da Hora Passos, Mauricio Reis Pedrosa, João Manoel da Silva Jr

Blood Pressure Variability in Stroke: Building a Framework, Conceptualizing Intervention Opportunities, and Identifying Practical Research Objectives

  • Open Access
  • Stroke
  • Response to Letter To The Editor

David Z. Rose, Alejandro A. Rabinstein, May Kim-Tenser, Sergio D. Bergese, Gabriel V. Fontaine, Charles Kircher, Adnan I. Qureshi

Does Celecoxib Actually Reduce Mortality in Patients with Spontaneous Intracerebral Hemorrhage?

Ravi Garg

Spontaneous Eye Blinking as a Potential Clinical Marker for Arousal in the Intensive Care Unit

  • Letters to the editor

Sarah Gharabaghi Stückler, Marwan H. Othman, Pardis Zarifkar, Daniel Kondziella

Publisher Correction: Systemic Metabolic Alterations After Aneurysmal Subarachnoid Hemorrhage: A Plasma Metabolomics Approach

Bosco Seong Kyu Yang, Jude P. J. Savarraj, Hua Chen, Sarah N. Hinds, Glenda L. Torres, Alice S. Ryan, Folefac D. Atem, Philip L. Lorenzi, Xuefang S. Ren, Louise D. McCullough, Neeraj Badjatia, Huimahn A. Choi, Aaron M. Gusdon

Dec 25
Issue: 3/2025

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Mini masterclass: enhancing outcomes in LGS (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)™

These six bite-sized videos will equip you with insights into the pathophysiological processes underlying Lennox–Gastaut syndrome, the burden on patients and caregivers, and opportunities to increase diagnostic accuracy and optimize treatment strategies.

Independent Medical Education Grant:
  • Jazz Pharmaceuticals
Watch now TODO (Link opens in a new window)

Keynote webinar | Spotlight on functional neurological disorder

FND perplexes and frustrates patients and physicians alike. Limited knowledge and insufficient awareness delays diagnosis and treatment, and many patients feel misunderstood and stigmatized. How can you recognize FND and what are the treatment options?

Prof. Mark Edwards
Watch now
Video
Image Credits
Enchancing Lennox-Gastaut Syndrome program image/© Springer Health+ IME, Human brain illustration/© (M) CHRISTOPH BURGSTEDT / SCIENCE PHOTO LIBRARY / Getty Images