Skip to main content
Top
Published in: Archives of Orthopaedic and Trauma Surgery 9/2022

Open Access 21-10-2021 | Nerve Block | Arthroscopy and Sports Medicine

A reduced concentration femoral nerve block is effective for perioperative pain control following ACL reconstruction: a retrospective review

Authors: Lukas N. Muench, Megan Wolf, Cameron Kia, Daniel P. Berthold, Mark P. Cote, Adam Fischler, Robert A. Arciero, Cory Edgar

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 9/2022

Login to get access

Abstract

Introduction

Femoral nerve block (FNB) is a routinely used regional analgesic technique for anterior cruciate ligament (ACL) reconstruction. One method to balance the analgesic effect and functional impairment of FNBs may be to control the concentration of local anesthetics utilized for the block.

Materials and methods

Retrospective chart review was performed on 390 consecutive patients who underwent ACL reconstruction between June 2014 and May 2017. Patients were divided into those who received a standard (0.5%-bupivacaine) or low (0.1–0.125%-bupivacaine) concentration single-shot FNB performed with ultrasound guidance. Maximum postoperative VAS, Post-Anaesthesia Care Unit (PACU) time prior to discharge, need for additional ‘rescue’ block, and intravenous postoperative narcotic requirements were recorded.

Results

A total of 268 patients (28.4 ± 11.9 years) were included for final analysis, with 72 patients in the low-concentration FNB group and 196 patients receiving the standard concentration. There were no differences in the maximum postoperative VAS between the low (6.4 ± 2.5) and standard (5.7 ± 2.9) concentration groups (P = 0.08). Similarly, the time from PACU arrival to discharge was not different between groups (P = 0.64). A sciatic rescue block was needed in 22% of patients with standard-dose FNB compared to 30% of patients receiving the low-concentration FNB (P = 0.20). Patients with a hamstring autograft harvest were more likely to undergo a postoperative sciatic rescue block compared to a bone-patellar tendon autograft (P = 0.005), regardless of preoperative block concentration. Quadriceps activation was preserved with low-concentration blocks.

Conclusions

Using 1/5th to 1/4th the standard local anesthetic concentration for preoperative femoral nerve block in ACL reconstruction did not significantly differ in peri-operative outcomes, PACU time, need for rescue blockade, or additional immediate opioid requirements.

Level of Evidence

III.
Literature
1.
go back to reference Albrecht E, Niederhauser J, Gronchi F et al (2011) Transient femoral neuropathy after knee ligament reconstruction and nerve stimulator-guided continuous femoral nerve block: a case series. Anaesthesia 66(9):849–850 CrossRef Albrecht E, Niederhauser J, Gronchi F et al (2011) Transient femoral neuropathy after knee ligament reconstruction and nerve stimulator-guided continuous femoral nerve block: a case series. Anaesthesia 66(9):849–850 CrossRef
2.
go back to reference Andrade R, Pereira R, van Cingel R, Staal JB, Espregueira-Mendes J (2019) How should clinicians rehabilitate patients after ACL reconstruction? A systematic review of clinical practice guidelines (CPGs) with a focus on quality appraisal (AGREE II). Br J Sports Med 54:512–519 CrossRef Andrade R, Pereira R, van Cingel R, Staal JB, Espregueira-Mendes J (2019) How should clinicians rehabilitate patients after ACL reconstruction? A systematic review of clinical practice guidelines (CPGs) with a focus on quality appraisal (AGREE II). Br J Sports Med 54:512–519 CrossRef
3.
go back to reference Andres-Cano P, Godino M, Vides M, Guerado E (2015) Postoperative complications of anterior cruciate ligament reconstruction after ambulatory surgery. Rev Esp Cir Ortop Traumatol 59(3):157–164 PubMed Andres-Cano P, Godino M, Vides M, Guerado E (2015) Postoperative complications of anterior cruciate ligament reconstruction after ambulatory surgery. Rev Esp Cir Ortop Traumatol 59(3):157–164 PubMed
4.
go back to reference Bertini L, Palmisani S, Mancini S, Martini O, Ioculano R, Arcioni R (2009) Does local anesthetic dilution influence the clinical effectiveness of multiple-injection axillary brachial plexus block?: a prospective, double-blind, randomized clinical trial in patients undergoing upper limb surgery. Reg Anesth Pain Med 34(5):408–413 CrossRef Bertini L, Palmisani S, Mancini S, Martini O, Ioculano R, Arcioni R (2009) Does local anesthetic dilution influence the clinical effectiveness of multiple-injection axillary brachial plexus block?: a prospective, double-blind, randomized clinical trial in patients undergoing upper limb surgery. Reg Anesth Pain Med 34(5):408–413 CrossRef
5.
go back to reference Cappelleri G, Aldegheri G, Ruggieri F, Carnelli F, Fanelli A, Casati A (2008) Effects of using the posterior or anterior approaches to the lumbar plexus on the minimum effective anesthetic concentration (MEAC) of mepivacaine required to block the femoral nerve: a prospective, randomized, up-and-down study. Reg Anesth Pain Med 33(1):10–16 PubMed Cappelleri G, Aldegheri G, Ruggieri F, Carnelli F, Fanelli A, Casati A (2008) Effects of using the posterior or anterior approaches to the lumbar plexus on the minimum effective anesthetic concentration (MEAC) of mepivacaine required to block the femoral nerve: a prospective, randomized, up-and-down study. Reg Anesth Pain Med 33(1):10–16 PubMed
6.
go back to reference Faul F, Erdfelder E, Lang AG, Buchner A (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39(2):175–191 CrossRef Faul F, Erdfelder E, Lang AG, Buchner A (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39(2):175–191 CrossRef
7.
go back to reference Frost S, Grossfeld S, Kirkley A, Litchfield B, Fowler P, Amendola A (2000) The efficacy of femoral nerve block in pain reduction for outpatient hamstring anterior cruciate ligament reconstruction: a double-blind, prospective, randomized trial. Arthroscopy 16(3):243–248 CrossRef Frost S, Grossfeld S, Kirkley A, Litchfield B, Fowler P, Amendola A (2000) The efficacy of femoral nerve block in pain reduction for outpatient hamstring anterior cruciate ligament reconstruction: a double-blind, prospective, randomized trial. Arthroscopy 16(3):243–248 CrossRef
8.
go back to reference Harris NJ, Bickerstaff DR, Farquharson D (1997) Post-operative analgesia following anterior cruciate ligament reconstruction: a controlled study using femoral nerve regional anaesthesia. Knee 4(4):197–201 CrossRef Harris NJ, Bickerstaff DR, Farquharson D (1997) Post-operative analgesia following anterior cruciate ligament reconstruction: a controlled study using femoral nerve regional anaesthesia. Knee 4(4):197–201 CrossRef
9.
go back to reference Höher J, Kersten D, Bouillon B, Neugebauer E, Tiling T (1997) Local and intra-articular infiltration of bupivacaine before surgery: effect on postoperative pain after anterior cruciate ligament reconstruction. Arthroscopy 13(2):210–217 CrossRef Höher J, Kersten D, Bouillon B, Neugebauer E, Tiling T (1997) Local and intra-articular infiltration of bupivacaine before surgery: effect on postoperative pain after anterior cruciate ligament reconstruction. Arthroscopy 13(2):210–217 CrossRef
10.
go back to reference Hsu LP, Oh S, Nuber GW et al (2013) Nerve block of the infrapatellar branch of the saphenous nerve in knee arthroscopy: a prospective, double-blinded, randomized, placebo-controlled trial. J Bone Joint Surg Am 95(16):1465–1472 CrossRef Hsu LP, Oh S, Nuber GW et al (2013) Nerve block of the infrapatellar branch of the saphenous nerve in knee arthroscopy: a prospective, double-blinded, randomized, placebo-controlled trial. J Bone Joint Surg Am 95(16):1465–1472 CrossRef
11.
go back to reference Jaksch W, Lang S, Reichhalter R, Raab G, Dann K, Fitzal S (2002) Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used. Anesth Analg 94(4):981–986 CrossRef Jaksch W, Lang S, Reichhalter R, Raab G, Dann K, Fitzal S (2002) Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used. Anesth Analg 94(4):981–986 CrossRef
12.
go back to reference Kristensen PK, Pfeiffer-Jensen M, Storm JO, Thillemann TM (2014) Local infiltration analgesia is comparable to femoral nerve block after anterior cruciate ligament reconstruction with hamstring tendon graft: a randomised controlled trial. Knee Surg Sports Traumatol Arthrosc 22(2):317–323 CrossRef Kristensen PK, Pfeiffer-Jensen M, Storm JO, Thillemann TM (2014) Local infiltration analgesia is comparable to femoral nerve block after anterior cruciate ligament reconstruction with hamstring tendon graft: a randomised controlled trial. Knee Surg Sports Traumatol Arthrosc 22(2):317–323 CrossRef
13.
go back to reference Kurosaka K, Tsukada S, Nakayama H et al (2018) Periarticular injection versus femoral nerve block for pain relief after anterior cruciate ligament reconstruction: a randomized controlled trial. Arthroscopy 34(1):182–188 CrossRef Kurosaka K, Tsukada S, Nakayama H et al (2018) Periarticular injection versus femoral nerve block for pain relief after anterior cruciate ligament reconstruction: a randomized controlled trial. Arthroscopy 34(1):182–188 CrossRef
14.
go back to reference Luo TD, Ashraf A, Dahm DL, Stuart MJ, McIntosh AL (2015) Femoral nerve block is associated with persistent strength deficits at 6 months after anterior cruciate ligament reconstruction in pediatric and adolescent patients. Am J Sports Med 43(2):331–336 CrossRef Luo TD, Ashraf A, Dahm DL, Stuart MJ, McIntosh AL (2015) Femoral nerve block is associated with persistent strength deficits at 6 months after anterior cruciate ligament reconstruction in pediatric and adolescent patients. Am J Sports Med 43(2):331–336 CrossRef
15.
go back to reference Mall NA, Chalmers PN, Moric M et al (2014) Incidence and trends of anterior cruciate ligament reconstruction in the United States. Am J Sports Med 42(10):2363–2370 CrossRef Mall NA, Chalmers PN, Moric M et al (2014) Incidence and trends of anterior cruciate ligament reconstruction in the United States. Am J Sports Med 42(10):2363–2370 CrossRef
16.
go back to reference Mehdi SA, Dalton DJ, Sivarajan V, Leach WJ (2004) BTB ACL reconstruction: femoral nerve block has no advantage over intraarticular local anaesthetic infiltration. Knee Surg Sports Traumatol Arthrosc 12(3):180–183 CrossRef Mehdi SA, Dalton DJ, Sivarajan V, Leach WJ (2004) BTB ACL reconstruction: femoral nerve block has no advantage over intraarticular local anaesthetic infiltration. Knee Surg Sports Traumatol Arthrosc 12(3):180–183 CrossRef
17.
go back to reference Peng P, Claxton A, Chung F, Chan V, Miniaci A, Krishnathas A (1999) Femoral nerve block and ketorolac in patients undergoing anterior cruciate ligament reconstruction. Can J Anaesth 46(10):919–924 CrossRef Peng P, Claxton A, Chung F, Chan V, Miniaci A, Krishnathas A (1999) Femoral nerve block and ketorolac in patients undergoing anterior cruciate ligament reconstruction. Can J Anaesth 46(10):919–924 CrossRef
18.
go back to reference Runner RP, Boden SA, Godfrey WS et al (2018) Quadriceps strength deficits after a femoral nerve block versus adductor canal block for anterior cruciate ligament reconstruction: a prospective, single-blinded, randomized trial. Orthop J Sports Med 6(9):2325967118797990 CrossRef Runner RP, Boden SA, Godfrey WS et al (2018) Quadriceps strength deficits after a femoral nerve block versus adductor canal block for anterior cruciate ligament reconstruction: a prospective, single-blinded, randomized trial. Orthop J Sports Med 6(9):2325967118797990 CrossRef
19.
go back to reference Sanders TL, Maradit Kremers H, Bryan AJ et al (2016) Incidence of anterior cruciate ligament tears and reconstruction: a 21-year population-based study. Am J Sports Med 44(6):1502–1507 CrossRef Sanders TL, Maradit Kremers H, Bryan AJ et al (2016) Incidence of anterior cruciate ligament tears and reconstruction: a 21-year population-based study. Am J Sports Med 44(6):1502–1507 CrossRef
20.
go back to reference Schloss B, Bhalla T, Klingele K, Phillips D, Prestwich B, Tobias JD (2014) A retrospective review of femoral nerve block for postoperative analgesia after knee surgery in the pediatric population. J Pediatr Orthop 34(4):459–461 CrossRef Schloss B, Bhalla T, Klingele K, Phillips D, Prestwich B, Tobias JD (2014) A retrospective review of femoral nerve block for postoperative analgesia after knee surgery in the pediatric population. J Pediatr Orthop 34(4):459–461 CrossRef
21.
go back to reference Secrist ES, Freedman KB, Ciccotti MG, Mazur DW, Hammoud S (2016) Pain management after outpatient anterior cruciate ligament reconstruction: a systematic review of randomized controlled trials. Am J Sports Med 44(9):2435–2447 CrossRef Secrist ES, Freedman KB, Ciccotti MG, Mazur DW, Hammoud S (2016) Pain management after outpatient anterior cruciate ligament reconstruction: a systematic review of randomized controlled trials. Am J Sports Med 44(9):2435–2447 CrossRef
22.
go back to reference Tetzlaff JE, Andrish J, O’Hara JJ, Dilger J, Yoon HJ (1997) Effectiveness of bupivacaine administered via femoral nerve catheter for pain control after anterior cruciate ligament repair. J Clin Anesth 9(7):542–545 CrossRef Tetzlaff JE, Andrish J, O’Hara JJ, Dilger J, Yoon HJ (1997) Effectiveness of bupivacaine administered via femoral nerve catheter for pain control after anterior cruciate ligament repair. J Clin Anesth 9(7):542–545 CrossRef
23.
go back to reference Veneziano G, Tripi J, Tumin D et al (2016) Femoral nerve blockade using various concentrations of local anesthetic for knee arthroscopy in the pediatric population. J Pain Res 9:1073–1079 CrossRef Veneziano G, Tripi J, Tumin D et al (2016) Femoral nerve blockade using various concentrations of local anesthetic for knee arthroscopy in the pediatric population. J Pain Res 9:1073–1079 CrossRef
24.
go back to reference Westergaard B, Jensen K, Lenz K et al (2014) A randomised controlled trial of ultrasound-guided blockade of the saphenous nerve and the posterior branch of the obturator nerve for postoperative analgesia after day-case knee arthroscopy. Anaesthesia 69(12):1337–1344 CrossRef Westergaard B, Jensen K, Lenz K et al (2014) A randomised controlled trial of ultrasound-guided blockade of the saphenous nerve and the posterior branch of the obturator nerve for postoperative analgesia after day-case knee arthroscopy. Anaesthesia 69(12):1337–1344 CrossRef
25.
go back to reference Widmer B, Lustig S, Scholes CJ et al (2013) Incidence and severity of complications due to femoral nerve blocks performed for knee surgery. Knee 20(3):181–185 CrossRef Widmer B, Lustig S, Scholes CJ et al (2013) Incidence and severity of complications due to femoral nerve blocks performed for knee surgery. Knee 20(3):181–185 CrossRef
26.
go back to reference Wulf H, Lowe J, Gnutzmann KH, Steinfeldt T (2010) Femoral nerve block with ropivacaine or bupivacaine in day case anterior crucial ligament reconstruction. Acta Anaesthesiol Scand 54(4):414–420 CrossRef Wulf H, Lowe J, Gnutzmann KH, Steinfeldt T (2010) Femoral nerve block with ropivacaine or bupivacaine in day case anterior crucial ligament reconstruction. Acta Anaesthesiol Scand 54(4):414–420 CrossRef
Metadata
Title
A reduced concentration femoral nerve block is effective for perioperative pain control following ACL reconstruction: a retrospective review
Authors
Lukas N. Muench
Megan Wolf
Cameron Kia
Daniel P. Berthold
Mark P. Cote
Adam Fischler
Robert A. Arciero
Cory Edgar
Publication date
21-10-2021
Publisher
Springer Berlin Heidelberg
Keyword
Nerve Block
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 9/2022
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-021-04221-3

Other articles of this Issue 9/2022

Archives of Orthopaedic and Trauma Surgery 9/2022 Go to the issue