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08-08-2022 | Necrotizing Fasciitis | Hospital-Based Dermatology (L Guggina and C Nguyen, Section Editors)

Cellulitis and Its Mimickers: an Approach to Diagnosis and Management

Authors: Bianca Biglione, Bethany Cucka, Daniela Kroshinsky

Published in: Current Dermatology Reports | Issue 3/2022

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Abstract

Purpose of Review

This article reviews the pathophysiology, clinical presentation, clinical mimickers, and management strategies for cellulitis in hospitalized patients.

Recent Findings

Cellulitis is a common skin infection with increasing hospitalizations and healthcare costs. The clinical presentation of cellulitis is mimicked by a wide spectrum of diagnoses including other infectious, inflammatory, vascular, and neoplastic conditions. Evaluating for and optimizing modifiable risk factors is paramount to treating cellulitis and preventing recurrences. These include local factors such as edema, previous cellulitis, skin barrier disruption due to trauma or pre-existing infection, skin inflammation, obesity, and immunosuppression.

Summary

Cellulitis is an infection of the deep dermis and subcutaneous tissue presenting with expanding erythema, edema, and warmth. Misdiagnosis is common and adds a significant burden to healthcare costs. A thorough history and physical examination can help distinguish cellulitis from its clinical mimickers. In addition to antimicrobial therapy, predisposing dermatological conditions should be addressed to prevent recurrences.
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Metadata
Title
Cellulitis and Its Mimickers: an Approach to Diagnosis and Management
Authors
Bianca Biglione
Bethany Cucka
Daniela Kroshinsky
Publication date
08-08-2022
Publisher
Springer US
Published in
Current Dermatology Reports / Issue 3/2022
Electronic ISSN: 2162-4933
DOI
https://doi.org/10.1007/s13671-022-00363-8