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Open Access 01-12-2025 | Myocardial Infarction | Research

Sex-specific outcome after minimally invasive direct coronary artery bypass for single-vessel disease: a propensity score matching analysis

Authors: Hao Ma, Fengbo Pei, Zengqiang Han, Bo Lian, Gang Liu, Yi Shi, Zhou Zhao

Published in: Journal of Cardiothoracic Surgery | Issue 1/2025

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Abstract

Objective

To evaluate the influence of gender on surgical outcome in patients with single-vessel disease undergoing minimally invasive direct coronary artery bypass (MIDCAB).

Methods

This retrospective, non-randomized study analyzed 471 patients who underwent MIDCAB between February 2012 and January 2021 through left lateral thoracic small incision in the Department of Cardiac Surgery of our hospital were selected. Data were collected on demographics, clinical characteristics, operative and postoperative outcomes, and follow-up mortality and morbidity. Propensity score matching (PSM) was used to match patients between the groups.

Results

Before matching, female patients were older, had higher incidence of DM (40.2% Vs 27.3%, p = 0.013), higher LVEF (66.7 ± 8.0 Vs 63.6 ± 10.1, p<0.001) and smaller LVEDD (4.7 ± 0.5 Vs 5.1 ± 0.6, p = 0.001). After matching, the differences in baseline characteristics between both groups were eliminated. PS matching selected 103 matched pairs for final comparison. No significant differences were observed between both groups in terms of in-hospital mortality, the incidence of MACCE, incidence of perioperative MI, incidence of stroke, reoperation for bleeding. Female patients had longer length of stay compared to male patients (18.9 ± 14.3 Vs 15.5 ± 5.9, p = 0.027).

Conclusion

Female sex is not connected with higher risk of mortality or other major events in MIDCAB. Wound healing complications remain the leading attribute associated with female sex.
Literature
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Metadata
Title
Sex-specific outcome after minimally invasive direct coronary artery bypass for single-vessel disease: a propensity score matching analysis
Authors
Hao Ma
Fengbo Pei
Zengqiang Han
Bo Lian
Gang Liu
Yi Shi
Zhou Zhao
Publication date
01-12-2025
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2025
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-024-03163-2
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