Multiple myeloma complicated with spinal infiltration: a case report
- 10-09-2025
- Multiple Myeloma
- Letter to the Editor
- Authors
- Man Guo
- Guohui Zhao
- Zhenyu Zhang
- Jie Zhou
- Published in
- Neurological Sciences
Excerpt
MM is a frequently encountered malignant hematological disorder, typically localized within the bone marrow. A subset of patients may develop extramedullary manifestations, with metastasis to other soft tissues and potential involvement of multiple organs and tissues, either as the initial presenting symptom or concurrently. Literature indicates that the incidence of extramedullary spread at the time of diagnosis of multiple myeloma ranges from 7 to 18%, with an additional 20% experiencing extramedullary spread during the course of treatment [1]. Extramedullary plasmacytomas (EMPs) within the spinal canal can precipitate severe spinal cord compression syndrome (SCCS), which is characterized by rapid disease progression. Despite this, there remains a significant debate surrounding the optimal management of MM patients who develop SCCS. …
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- Title
- Multiple myeloma complicated with spinal infiltration: a case report
- Authors
-
Man Guo
Guohui Zhao
Zhenyu Zhang
Jie Zhou
- Publication date
- 10-09-2025
- Publisher
- Springer International Publishing
- Published in
-
Neurological Sciences
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478 - DOI
- https://doi.org/10.1007/s10072-025-08481-4
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