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Successful sequential application of CAR T-cell-therapies in relapsed refractory multiple myeloma

Published in:

Abstract

We here report on a patient with relapsed-refractory multiple myeloma (RRMM) who received chimeric antigen receptor (CAR) T-cells (Ciltacabtagene Autoleucel, cilta-cel, Carvykti®) after achieving a partial but not durable remission with Idecabtagene Vicleucel (ide-cel, Abecma®). Both CAR T-cells target the B-cell maturation antigen (BCMA) and their sequential use is as yet rare, thus data on safety and efficacy of their sequential employment are precious and relevant for the myeloma commmunity.
Title
Successful sequential application of CAR T-cell-therapies in relapsed refractory multiple myeloma
Authors
Paul Mobascher
Monika Engelhardt
Ralph Wäsch
Publication date
03-04-2025
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 3/2025
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-025-06340-y
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