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16-01-2024 | Mild Neurocognitive Disorder | Sleep Breathing Physiology and Disorders • Original Article

Continuous positive airway pressure compliance in patients with mild cognitive impairment

Authors: Raphaël Briand, Thibaud Lebouvier, Lise Lanvin, Nassima Ramdane, Emilie Skrobala, Mélanie Leroy, Cécile Chenivesse, Stéphanie Fry, Olivier Le Rouzic

Published in: Sleep and Breathing | Issue 3/2024

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Abstract

Purpose

Sleep apnoea (SA) is associated with accelerated cognitive decline in patients with mild cognitive impairment (MCI). Treatment of SA by continuous positive airway pressure (CPAP) may slow this decline if patients comply with the treatment. The aim of this study was to assess the rate of CPAP compliance in this population.

Methods

In this single-centre retrospective study conducted in a tertiary care institution, patients with a diagnosis of MCI and SA initiating CPAP between January 2015 and August 2021 were included. Data from the initial sleep recording, the 3-month follow-up and compliance with at least 12 months of CPAP were analysed. Compliance was defined as an average CPAP use of at least 4 h per night.

Results

55 patients were included (49% women, age 70.7 ± 8.9 years, body mass index 28.9 ± 6.5 kg/m2). Aetiology of MCI was vascular (45.5%), psychiatric (12.7%) and related to Alzheimer’s disease (7.3%), with 47.3% of amnesic disorders and 45.5% of dysexecutive disorders. The MiniMentalState score was 26.7 ± 3.1. SA was mostly obstructive (81.8%) with a mean apnoea-hypopnoea index of 41.1 ± 16.4/h. At 3 months, 38 patients were compliant (69%) with a CPAP median use of 5.9 h per night and 83% of nights. Self-reported tolerance was better in compliant patients (75.7% vs 38.5% p = 0.017). Thirty-four patients remained compliant at 12 months (62%).

Conclusion

Our results suggest a high rate of CPAP compliance in patients suffering from MCI. Compliance was related to the device tolerance, emphasizing the need to closely monitor and improve this factor.
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Literature
9.
go back to reference Crawford-Achour E, Dauphinot V, Saint Martin M et al (2015) Protective Effect of Long-Term CPAP Therapy on Cognitive Performance in Elderly Patients with Severe OSA: The PROOF Study. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med 11:519–524. https://doi.org/10.5664/jcsm.4694CrossRef Crawford-Achour E, Dauphinot V, Saint Martin M et al (2015) Protective Effect of Long-Term CPAP Therapy on Cognitive Performance in Elderly Patients with Severe OSA: The PROOF Study. J Clin Sleep Med JCSM Off Publ Am Acad Sleep Med 11:519–524. https://​doi.​org/​10.​5664/​jcsm.​4694CrossRef
21.
go back to reference Richards KC, Vallabhaneni V, Moelter S et al (2020) 0861 Age, Race, And Continuous Positive Airway Pressure (CPAP) Confidence Score At 1-week Predict 3-month CPAP Adherence In Older Adults With Amnestic Mild Cognitive Impairment And Moderate To Severe Obstructive Sleep Apnea. Sleep 43:A328. https://doi.org/10.1093/sleep/zsaa056.857CrossRef Richards KC, Vallabhaneni V, Moelter S et al (2020) 0861 Age, Race, And Continuous Positive Airway Pressure (CPAP) Confidence Score At 1-week Predict 3-month CPAP Adherence In Older Adults With Amnestic Mild Cognitive Impairment And Moderate To Severe Obstructive Sleep Apnea. Sleep 43:A328. https://​doi.​org/​10.​1093/​sleep/​zsaa056.​857CrossRef
Metadata
Title
Continuous positive airway pressure compliance in patients with mild cognitive impairment
Authors
Raphaël Briand
Thibaud Lebouvier
Lise Lanvin
Nassima Ramdane
Emilie Skrobala
Mélanie Leroy
Cécile Chenivesse
Stéphanie Fry
Olivier Le Rouzic
Publication date
16-01-2024
Publisher
Springer International Publishing
Published in
Sleep and Breathing / Issue 3/2024
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-024-02995-5

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