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METTL3-mediated m6A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca2+ signaling

  • Open Access
  • 19-01-2026
  • Research
Title
METTL3-mediated m6A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca2+ signaling
Authors
Chaotao Chen
Kai Xiong
Feiyuan Liang
Yanping Zhong
Xiong Qin
Nanchang Huang
Yuqi Fang
Bo Zhu
Jianwen Cheng
Qingjun Wei
Li Zheng
Jinmin Zhao
Publication date
19-01-2026
Publisher
BioMed Central
Published in
Molecular Cancer
Electronic ISSN: 1476-4598
DOI
https://doi.org/10.1186/s12943-025-02553-x

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Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images