European Archives of Oto-Rhino-Laryngology

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Open Access 22-05-2023 | Metastasis | Head and Neck

Incidence and spread pattern of lymph node metastasis from submandibular gland cancer

Authors: Kotaro Tamagawa, Naoki Otsuki, Hikari Shimoda, Naruhiko Morita, Tatsuya Furukawa, Masanori Teshima, Hirotaka Shinomiya, Ken-ichi Nibu

Published in: European Archives of Oto-Rhino-Laryngology | Issue 9/2023

Abstract

Objectives

To clarify the indication of neck dissection (ND) for patient with submandibular gland (SMG) cancer.

Methods

A total of 43 patients with SMG cancer were retrospectively analyzed. Forty-one patients underwent ND: Levels I–V in 19 patients, Levels I–III in 18 patients, and Level Ib in 4 patients. The other two patients did not undergo ND, since preoperative diagnoses were benign. Postoperative radiotherapy was performed in 19 patients with positive surgical margin, high grade cancer or stage IV disease.

Results

LN metastases were pathologically confirmed in all patients with cN + and 6 out of 31 patients with cN–. No patients developed regional recurrence during follow-up periods. Ultimately, LN metastases were pathologically confirmed in 17 of 27 high grade, one out of 9 intermediate grade, but not in 7 low grade.

Conclusions

Prophylactic neck dissection should be considered in T3/4 and high grade SMG cancers.

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Title: Incidence and spread pattern of lymph node metastasis from submandibular gland cancer
Authors: Kotaro Tamagawa
Naoki Otsuki
Hikari Shimoda
Naruhiko Morita
Tatsuya Furukawa
Masanori Teshima
Hirotaka Shinomiya
Ken-ichi Nibu
Publication date: 22-05-2023
Publisher: Springer Berlin Heidelberg
Keywords: Metastasis
Neck Dissection
Radiotherapy
Published in: European Archives of Oto-Rhino-Laryngology / Issue 9/2023
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08020-x

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Abstract

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