Skip to main content
Top
Published in:

Open Access 01-12-2024 | Metastasis | Case Report

Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report

Authors: Lanyue Huang, Yanhui Li, Rui Li, Houjuan Zuo, Daowen Wang, Hesong Zeng, Peng Deng, Ligang Liu, Xiang Wei, Jingqun Zhang

Published in: World Journal of Surgical Oncology | Issue 1/2024

Login to get access

Abstract

Background

Metastasis of malignant tumors to the cardiac endocardium is rare and mainly involves the right side of the heart. It is extremely rare to involve the left cardiac endocardium, especially when there is neither pulmonary metastasis nor primary lung cancer, which we call “isolated” left cardiac endocardium metastasis in this paper. Few such cases previously reported in the literature were not screened for patent foramen ovale (PFO).

Case presentation

This article reports a case of a young woman with a history of surgery for cervical cancer, who was transferred to our hospital with a suspected diagnosis of PFO after recent recurrent multiple cerebral infarctions. On admission, transthoracic echocardiography revealed multiple stringy vegetations in the left ventricle, which were subsequently removed surgically, with intraoperative confirmation of a patent foramen ovale and closure of it simultaneously. According to her medical history and pathological results, she was diagnosed with left ventricular metastasis of cervical cancer, a rare case of isolated left heart endocardium metastasis without previous pulmonary metastasis, presumably through the patent foramen ovale.

Conclusion

PFO may play an important role in the process of isolated left heart endocardium metastasis in patients with distant malignancies and paradoxical embolism. Screening for PFO in high-risk patients may have significant clinical significance.
Appendix
Available only for authorised users
Literature
1.
go back to reference Byun SW, Park ST, Ki EY et al. Intracardiac metastasis from known cervical cancer: a case report and literature review. World J Surg Oncol, 2013, 11. Byun SW, Park ST, Ki EY et al. Intracardiac metastasis from known cervical cancer: a case report and literature review. World J Surg Oncol, 2013, 11.
2.
go back to reference Jian-Qiang M, a O, Li-Jin Z, Yi-Min X. One case report of left ventricular metastatic malignant tumor. J Shanghai Jiaotong Univ. 2009;29(1):120–120. Jian-Qiang M, a O, Li-Jin Z, Yi-Min X. One case report of left ventricular metastatic malignant tumor. J Shanghai Jiaotong Univ. 2009;29(1):120–120.
3.
go back to reference Guowei C, Qinghua Z. Simultaneous operation of Lung Cancer Metastatic to Left ventricle and review of the literatures. Chin J Lung Cancer. 2009;12(6):527–9. Guowei C, Qinghua Z. Simultaneous operation of Lung Cancer Metastatic to Left ventricle and review of the literatures. Chin J Lung Cancer. 2009;12(6):527–9.
4.
go back to reference Shah AH, Horlick EM, Kass M et al. The pathophysiology of patent Foramen Ovale and its related complications. Am Heart J, 2024: 186–8. Shah AH, Horlick EM, Kass M et al. The pathophysiology of patent Foramen Ovale and its related complications. Am Heart J, 2024: 186–8.
5.
go back to reference Schawkat K, Hoksch B, Schwerzmann M, et al. Diagnosis of cardiac metastasis from cervical cancer in a 33-year-old patient using multimodal imaging studies: a case report and literature review. Acta Radiol Short Rep. 2014;3(8):2047981614530287–2047981614530287.PubMedPubMedCentral Schawkat K, Hoksch B, Schwerzmann M, et al. Diagnosis of cardiac metastasis from cervical cancer in a 33-year-old patient using multimodal imaging studies: a case report and literature review. Acta Radiol Short Rep. 2014;3(8):2047981614530287–2047981614530287.PubMedPubMedCentral
6.
go back to reference Saitoh Y, Aota M, Koike H, et al. Isolated right ventricular metastasis of uterine cervical carcinoma. Jpn J Thorac Cardiovasc Surg. 2005;53(12):645–8.CrossRefPubMed Saitoh Y, Aota M, Koike H, et al. Isolated right ventricular metastasis of uterine cervical carcinoma. Jpn J Thorac Cardiovasc Surg. 2005;53(12):645–8.CrossRefPubMed
7.
8.
go back to reference Nakayama R, Takaya Y, Akagi T, et al. Identification of high-risk patent Foramen Ovale Associated with Cryptogenic Stroke: development of a Scoring System. J Am Soc Echocardiogr. 2019;32(7):811–6.CrossRefPubMed Nakayama R, Takaya Y, Akagi T, et al. Identification of high-risk patent Foramen Ovale Associated with Cryptogenic Stroke: development of a Scoring System. J Am Soc Echocardiogr. 2019;32(7):811–6.CrossRefPubMed
9.
go back to reference Riccioni L, Damiani S, Pasquinelli G, et al. Solitary left ventricle metastasis by renal cell carcinoma with sarcomatoid features. Tumori. 1996;82(3):266–9.PubMed Riccioni L, Damiani S, Pasquinelli G, et al. Solitary left ventricle metastasis by renal cell carcinoma with sarcomatoid features. Tumori. 1996;82(3):266–9.PubMed
10.
go back to reference Bradley SM, Bolling SF. Late renal cell carcinoma metastasis to the left ventricular outflow tract. Ann Thorac Surg. 1995;60(1):204–6.CrossRefPubMed Bradley SM, Bolling SF. Late renal cell carcinoma metastasis to the left ventricular outflow tract. Ann Thorac Surg. 1995;60(1):204–6.CrossRefPubMed
11.
go back to reference Ishiko R, Yamasaki J, Kasahara T, et al. Metastatic tumor of the heart from gall bladder cancer detected by echocardiography: a case report. J Cardiol. 1987;17(3):653–8.PubMed Ishiko R, Yamasaki J, Kasahara T, et al. Metastatic tumor of the heart from gall bladder cancer detected by echocardiography: a case report. J Cardiol. 1987;17(3):653–8.PubMed
12.
go back to reference Cordioli E, Pizzi C, Bugiardini R. Left ventricular metastasis from uterine leiomyosarcoma. Cardiologia (Rome Italy). 1999;44(11):1001–3.PubMed Cordioli E, Pizzi C, Bugiardini R. Left ventricular metastasis from uterine leiomyosarcoma. Cardiologia (Rome Italy). 1999;44(11):1001–3.PubMed
13.
go back to reference Zhu L-K, Li Z-J, Wang Z-B et al. A rare case of bladder cancer that metastasized to brain, heart, and lung lymph nodes benefited from immunotherapy. World J Surg Oncol, 2022, 20(1). Zhu L-K, Li Z-J, Wang Z-B et al. A rare case of bladder cancer that metastasized to brain, heart, and lung lymph nodes benefited from immunotherapy. World J Surg Oncol, 2022, 20(1).
14.
go back to reference Shang W, Lu Z, Haibo Y. A case of misdiagnose of non-gestational choriocarcinoma metastasis to left atrium. Chin J Cardiol. 2019;47(7):575–6. Shang W, Lu Z, Haibo Y. A case of misdiagnose of non-gestational choriocarcinoma metastasis to left atrium. Chin J Cardiol. 2019;47(7):575–6.
Metadata
Title
Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report
Authors
Lanyue Huang
Yanhui Li
Rui Li
Houjuan Zuo
Daowen Wang
Hesong Zeng
Peng Deng
Ligang Liu
Xiang Wei
Jingqun Zhang
Publication date
01-12-2024
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2024
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-024-03603-2
SPONSORED

Mastering chronic pancreatitis pain: A multidisciplinary approach and practical solutions

  • Webinar | 06-02-2024 | 20:00 (CET)

Severe pain is the most common symptom of chronic pancreatitis. In this webinar, experts share the latest insights in pain management for chronic pancreatitis patients. Experts from a range of disciplines discuss pertinent cases and provide practical suggestions for use within clinical practice.

Sponsored by:
  • Viatris
Developed by: Springer Healthcare
Watch now