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Current Nutrition Reports

Metabolomics and Transcriptomics of Metabolic Disorders

  • 01-12-2013
  • Diabetes and Obesity (A Sánchez-Villegas, Section Editor)
Published in:
Authors
Laura Paternain
Javier Campion
Published in
Current Nutrition Reports | Issue 4/2013

Abstract

The current prevalence of metabolic diseases such as obesity and type 2 diabetes mellitus (T2DM) is increasing not only due to genetic causes, but also because of lifestyle factors such as lack of physical exercise and consumption of high fat and high glycemic index diets, being one of the most serious public health problems around the world. Different omic approaches such as metabolomics or transcriptomics have revolutionized the quantitative analysis of an organism’s state, linking cellular pathways to biological mechanisms, and could be applicable for identifying metabolic markers, which could be useful as diagnostic tools in a personalized healthcare setting. It may also open the door to novel biomarker discovery, disease diagnosis, and novel therapeutic avenues. This review covers the metabolomics and transcriptomic studies analyzing different biomarkers involved in the development of obesity and T2DM.
Title
Metabolomics and Transcriptomics of Metabolic Disorders
Authors
Laura Paternain
Javier Campion
Publication date
01-12-2013
Publisher
Springer US
Published in
Current Nutrition Reports / Issue 4/2013
Electronic ISSN: 2161-3311
DOI
https://doi.org/10.1007/s13668-013-0062-2
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