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Open Access 11-01-2025 | Metabolic Dysfunction-Associated Steatotic Liver Disease | REVIEW

Nutritional Strategies for Battling Obesity-Linked Liver Disease: the Role of Medical Nutritional Therapy in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Management

Authors: Daniel Simancas-Racines, Giuseppe Annunziata, Ludovica Verde, Federica Fascì-Spurio, Claudia Reytor-González, Giovanna Muscogiuri, Evelyn Frias-Toral, Luigi Barrea

Published in: Current Obesity Reports | Issue 1/2025

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Abstract

Purpose of Review

This narrative review explores the role of Medical Nutritional Therapy (MNT) in managing Metabolic-Associated Steatotic Liver Disease (MASLD), previously known as nonalcoholic fatty liver disease. It aims to examine the effectiveness of specific nutritional strategies in preventing and treating this obesity-linked liver disease.

Recent Findings

Emerging evidence underscores the benefits of the Mediterranean diet, low-carbohydrate diets, and intermittent fasting in reducing liver fat, improving insulin sensitivity, and mitigating inflammation. Supplementing with vitamin E, omega-3 fatty acids, and silymarin can potentially reduce liver fibrosis and promote liver health.

Summary

MNT is a key intervention for MASLD management, emphasizing dietary patterns, caloric restriction, and nutraceutical supplementation. Integrating these strategies with lifestyle modifications, including regular physical activity, offers a comprehensive approach to improving metabolic and liver outcomes in patients with MASLD. Further research is needed to refine and personalize these therapeutic interventions.
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Metadata
Title
Nutritional Strategies for Battling Obesity-Linked Liver Disease: the Role of Medical Nutritional Therapy in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Management
Authors
Daniel Simancas-Racines
Giuseppe Annunziata
Ludovica Verde
Federica Fascì-Spurio
Claudia Reytor-González
Giovanna Muscogiuri
Evelyn Frias-Toral
Luigi Barrea
Publication date
11-01-2025

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