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06-09-2024 | Meningioma | Case Report

Malignant meningioma of the falx cerebri in a child: case report and literature review

Authors: Rongzeng Guo, Changxiang Yan, Xiaojun Fu

Published in: Child's Nervous System

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Abstract

Meningiomas are common intracranial tumors in adults but rare in pediatric cases, with malignant histological features being even less frequent. Primary pediatric malignant meningioma of the falx cerebri has not been previously reported in the literature. We present a case of a malignant meningioma of the falx cerebri in a child who was admitted to the hospital following head trauma, presenting with mental impairment and limb weakness. CT examination revealed a right parietal epidural hematoma and a large intracranial lesion. The patient underwent drainage of the intracranial hematoma and a two-frontal craniotomy with tumor resection under microscopy. Histopathological analysis confirmed malignant meningioma, and genetic testing identified a YAP1-MAML2 gene fusion. There is no consensus on the clinical, imaging, and pathological features of pediatric meningiomas. In this paper, we discuss the clinical features, diagnostic and treatment protocols, and pathological characteristics of this case, along with a review of the relevant literature.
Literature
Metadata
Title
Malignant meningioma of the falx cerebri in a child: case report and literature review
Authors
Rongzeng Guo
Changxiang Yan
Xiaojun Fu
Publication date
06-09-2024
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-024-06600-8

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