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01-12-2022 | Malaria | Research article

Factors associated with prolonged hospital stay of imported malaria cases in Chengdu, China: a retrospective study

Authors: Liang Huang, Hong Jin, Hong Zhang, Yang Liu, Xinxing Shi, Xintong Kang, Yilan Zeng, Lin Wang

Published in: BMC Infectious Diseases | Issue 1/2022

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Abstract

Background

Although China has entered the post-malaria-elimination era, imported cases remain a public health concern in China.

Methods

We retrospectively analyzed data from cases of imported malaria from January 2017 to December 2020 in Chengdu Public Health Clinical Center. We assessed potential clinical, epidemiological, geographical, and seasonal effects on duration of hospital stay. Cox proportional hazards model was used to identify predictive factors for prolonged hospital stay. Multivariate logistic regression was used to assess the potential risk factors associated with severe cases.

Results

The highest number of imported cases of malaria were from the Democratic Republic of the Congo (23%, 34/150) and most patients (74%, 26/34) were infected by Plasmodium falciparum. The Edwards test indicated no significant seasonality in imported cases of malaria (χ2 = 2.51, p = 0.28). Bacterial infection (adjusted hazard ratio [aHR] for discharge = 0.58, p = 0.01) and thrombocytopenia (aHR = 0.66, p = 0.02) were risk factors for prolonged hospital stay. The C-reactive protein (OR = 1.02, p = 0.01) and procalcitonin (OR = 1.03, p = 0.01) were risk factors for severe cases.

Conclusions

Bacterial infection and thrombocytopenia are risk factors for prolonged hospital stay among imported malaria cases. The C-reactive protein and procalcitonin level were risk factors for severe cases.
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Metadata
Title
Factors associated with prolonged hospital stay of imported malaria cases in Chengdu, China: a retrospective study
Authors
Liang Huang
Hong Jin
Hong Zhang
Yang Liu
Xinxing Shi
Xintong Kang
Yilan Zeng
Lin Wang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-022-07464-6

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