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Skeletal Radiology
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Open Access 09-07-2024 | Magnetic Resonance Imaging | Review Article

Cartilage compositional MRI—a narrative review of technical development and clinical applications over the past three decades

Authors: Xiaojuan Li, Jeehun Kim, Mingrui Yang, Ahmet H. Ok, Štefan Zbýň, Thomas M. Link, Sharmilar Majumdar, C. Benjamin Ma, Kurt P. Spindler, Carl S. Winalski

Published in: Skeletal Radiology | Issue 9/2024

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Abstract

Articular cartilage damage and degeneration are among hallmark manifestations of joint injuries and arthritis, classically osteoarthritis. Cartilage compositional MRI (Cart-C MRI), a quantitative technique, which aims to detect early-stage cartilage matrix changes that precede macroscopic alterations, began development in the 1990s. However, despite the significant advancements over the past three decades, Cart-C MRI remains predominantly a research tool, hindered by various technical and clinical hurdles. This paper will review the technical evolution of Cart-C MRI, delve into its clinical applications, and conclude by identifying the existing gaps and challenges that need to be addressed to enable even broader clinical application of Cart-C MRI.
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Metadata
Title
Cartilage compositional MRI—a narrative review of technical development and clinical applications over the past three decades
Authors
Xiaojuan Li
Jeehun Kim
Mingrui Yang
Ahmet H. Ok
Štefan Zbýň
Thomas M. Link
Sharmilar Majumdar
C. Benjamin Ma
Kurt P. Spindler
Carl S. Winalski
Publication date
09-07-2024
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 9/2024
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-024-04734-z

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