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Open Access 06-09-2024 | Lung Cancer

Symptom clusters and impact on quality of life in lung cancer patients undergoing chemotherapy

Authors: Yuanyuan Luo, Le Zhang, Dongmei Mao, Zhihui Yang, Benxiang Zhu, Jingxia Miao, Lili Zhang

Abstract

Purpose

To identify symptom clusters (SCs) in lung cancer patients undergoing chemotherapy and explore their impact on health-related quality of life (HRQoL).

Methods

Patients were invited to complete the Chinese version of the M.D. Anderson Symptom Inventory with the Lung Cancer Module and the Quality of Life Questionnaire-core 30. Network analysis was employed to identify SCs. The associations between SCs and each function of HRQoL were examined using the Pearson correlation matrix. Multiple linear regression was applied to analyze the influencing factors of each function of HRQoL.

Results

A total of 623 lung cancer patients who were receiving chemotherapy were recruited. The global health status of lung cancer patients was 59.71 ± 21.09, and 89.73% of patients developed symptoms. Three SCs (Somato-psychological SC, Respiratory SC, and Gastrointestinal SC) were identified, and Somato-psychological SC and Gastrointestinal SC were identified as influencing factors for HRQoL in lung cancer patients.

Conclusion

Most lung cancer patients who undergo chemotherapy experience a range of symptoms, which can be categorized into three SCs. The Somato-psychological SC and Gastrointestinal SC negatively impacted patients' HRQoL. Health care providers should prioritize monitoring these SCs to identify high-risk patients early and implement targeted preventive and intervention measures for each SC, aiming to alleviate symptom burden and enhance HRQoL.

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Title: Symptom clusters and impact on quality of life in lung cancer patients undergoing chemotherapy
Authors: Yuanyuan Luo
Le Zhang
Dongmei Mao
Zhihui Yang
Benxiang Zhu
Jingxia Miao
Lili Zhang
Publication date: 06-09-2024
Publisher: Springer International Publishing
Keywords: Lung Cancer
Lung Cancer
Lung Cancer
Cytostatic Therapy
Published in: Quality of Life Research
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-024-03778-x

Keynote webinar | Spotlight on modern management of frailty

Springer Medicine

Symptom clusters and impact on quality of life in lung cancer patients undergoing chemotherapy

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on modern management of frailty

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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