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Early menopause increases lung disease risk

Menopause before the age of 45 years increases the risk for lung morbidities and mortality in women, regardless of smoking status and whether menopause is natural or medical.

Editor's Choice

A challenging diagnosis of lung cancer

Open Access Lung Cancer Case Study

Although uncommon, lung cancer in patients with granulomatosis with polyangiitis can be difficult to diagnose due to similarities in imaging findings.

Bronchopleural fistula after neoadjuvant immunochemotherapy

Bronchopleural fistula is a rare but potentially fatal complication that can occur after surgery in patients receiving neoadjuvant immunochemotherapy for stage III NSCLC.

Late onset of immune checkpoint inhibitor-induced type 1 diabetes

Open Access Type 1 Diabetes Case Study

A patient with small-cell lung cancer developed type 1 diabetes many weeks after receiving serplulimab, highlighting the need for continued monitoring of blood glucose levels and early signs and symptoms of diabetes.

Asbestos-related lung disorders

Exposure to asbestos is associated with various pathologies, such as asbestosis, mesothelioma, and pleural plaques. As treatment for these disorders is not curative, the main aim should be to limit exposure.

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Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine

Case Studies

A challenging diagnosis of lung cancer

Open Access Lung Cancer Case Study

Although uncommon, lung cancer in patients with granulomatosis with polyangiitis can be difficult to diagnose due to similarities in imaging findings.

Bronchopleural fistula after neoadjuvant immunochemotherapy

Bronchopleural fistula is a rare but potentially fatal complication that can occur after surgery in patients receiving neoadjuvant immunochemotherapy for stage III NSCLC.

Rare example of a metastatic brain tumor infiltrating a meningioma

Open Access Meningioma Case Study

Tumor-to-tumor metastasis is the most common extracranial cancer metastasis to existing brain tumors, whereas a rare form is metastasis infiltrating tumor. In this case, a lung cancer tumor metastasized adjacent to and partially infiltrated an existing meningioma.

Case-Based Insights: Oncology and Hematology (Link opens in a new window)


Refresh your knowledge in Oncology and Hematology: 

  • 45 clinical cases across different topics with relevant clinical images
  • Written by renowned experts 
  • Knowledge-check questions with answers
Try the first set of cases now

Current Reviews

The pros and cons of lung cancer screening

Open Access Lung Cancer Invited Review

Lung cancer (LC) is the leading cause of cancer-related death worldwide [ 1 ]. The premise of lung cancer screening (LCS) is that early detection of LC reduces mortality. Indeed, low-dose computed tomography (LDCT)-based LCS showed a 20–39% …

RET Inhibitors in RET Fusion-Positive Lung Cancers: Past, Present, and Future

NSCLC Review Article

While activating RET fusions are identified in various cancers, lung cancer represents the most common RET fusion-positive tumor. The clinical drug development of RET inhibitors in RET fusion-positive lung cancers naturally began after RET fusions …

Deep learning in pulmonary nodule detection and segmentation: a systematic review

Open Access Pulmonary Nodule Review

Lung cancer is responsible for 18.4% of all cancer deaths globally and is the leading cause of cancer-related mortality worldwide [ 1 ]. Pulmonary nodules, often an early indicator of lung cancer, do not always indicate malignancy [ 2 ]. Early …

Emerging Roles of Galectin-3 in Pulmonary Diseases

Galectin-3 is a multifunctional protein that is involved in various physiological and pathological events. Emerging evidence suggests that galectin-3 also plays a critical role in the pathogenesis of pulmonary diseases. Galectin-3 can be produced …

CME & eLearning

eLearning | Interviews | Digital Treatment Map (Link opens in a new window)

1.0 AMA PRA Category 1 Credit(s)

Expert-led, multiformat program which will address the individualized management of NSCLC, through education on the detection of NTRK gene fusions, current evidence-based guidelines, and new and emerging therapies. Will also include guidance on integrating shared decision making into your clinical practice, drawing on insights from a patient on how best to communicate.

Supported by:
  • Bayer HealthCare Pharmaceuticals Inc.
Developed by: Springer Healthcare IME

Further Reading

Combining [177Lu]Lu-DOTA-TOC PRRT with PARP inhibitors to enhance treatment efficacy in small cell lung cancer

Open Access SCLC Original Article

Small cell lung cancer (SCLC) is a highly aggressive tumor associated with early metastasis formation and – despite often a good response to initial therapy – a 5-year survival rate of less than 10% [ 1 ]. For limited-stage disease, the current …

The pros and cons of lung cancer screening

Open Access Lung Cancer Invited Review

Lung cancer (LC) is the leading cause of cancer-related death worldwide [ 1 ]. The premise of lung cancer screening (LCS) is that early detection of LC reduces mortality. Indeed, low-dose computed tomography (LDCT)-based LCS showed a 20–39% …

Detection of pulmonary nodules in chest radiographs: novel cost function for effective network training with purely synthesized datasets

Open Access Lung Cancer Original Article

Lung cancer, one of the most common malignant tumors worldwide, caused 1.79 million deaths in 2020 [ 1 ]. Computed tomography (CT) is the gold standard among imaging examinations for diagnosing lung cancer. However, due to its costs and radiation …

A DPC Database Study on the Safety of Atezolizumab/Carboplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer in Japanese Patients

Open Access SCLC Original Research

Lung cancer is a highly prevalent malignant disease and the most common cause of cancer-related deaths worldwide; in Japan, approximately 75,585 deaths (53,247 men and 22,338 women) in 2020 were due to lung cancer [ 1 ]. Approximately 10–15% of all …