Extracellular Vesicles in Heart Disease: Excitement for the Future?

Authors

  • Kirsty M. Danielson Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA
  • Saumya Das Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA

DOI:

https://doi.org/10.33393/jcb.2014.2040

Keywords:

Exosome, Microvesicle, Apoptotic Bodies, Cardiovascular Disease

Abstract

Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including proteins, lipids and nucleic acids. The role of EVs in cardiac physiology and heart disease is an emerging field that has produced intriguing findings in recent years. This review will outline what is currently known about EVs in the cardiovascular system, including cellular origins, functional roles and utility as biomarkers and potential therapeutics.

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Published

2014-01-01

How to Cite

Danielson, K. M., & Das, S. (2014). Extracellular Vesicles in Heart Disease: Excitement for the Future?. Journal of Circulating Biomarkers, 2(1). https://doi.org/10.33393/jcb.2014.2040

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