Dental Materials Journal
Online ISSN : 1881-1361
Print ISSN : 0287-4547
ISSN-L : 0287-4547
Original papers
Guinea Pig Maximization Test of Tri-ethylene Glycol Mono-methacrylate
Takashi AKIYAMAAtsufumi MANABEChihiro TANIYoichi TAKAHASHIKazuo ITOHHisashi HISAMITSU
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JOURNAL FREE ACCESS

2007 Volume 26 Issue 3 Pages 312-315

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Abstract

The aim of this study was to evaluate tri-ethylene glycol mono-methacrylate (TEGMA) in terms of dermatological allergic reaction using a Guinea Pig Maximization Test. Skin reaction was evaluated according to the criteria of International Contact Dermatitis Research Group. TEGMA, as a constituent in new primers, has been reported to contribute to a priming ability similar to that of highly purified glyceryl mono-methacrylate (GM). In this study, it was found that its adverse effect was less than that of 2-hydroxy ethyl methacrylate (2-HEMA), but similar to that of highly purified GM. In conclusion, it was anticipated that TEGMA would hereafter replace 2-HEMA as a primer, as it posed a lower risk of triggering dermatological allergic reaction.

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© 2007 The Japanese Society for Dental Materials and Devices
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