Preoperative Identification of Subthalamic Nucleus for Deep Brain Stimulation Using Three-dimensional Phase Sensitive Inversion Recovery Technique

Takashi ISHIMORI; Satoru NAKANO; Yasutane MORI; Reiko SEO; Taro TOGAMI; Tetsuya MASADA; Toshiaki KUSUHARA; Motoomi OHKAWA; Seigo NAGAO; Yuichi YAMASHITA; Satoshi SUGIURA

doi:10.2463/mrms.6.225

Technical Notes

Preoperative Identification of Subthalamic Nucleus for Deep Brain Stimulation Using Three-dimensional Phase Sensitive Inversion Recovery Technique

Takashi ISHIMORI, Satoru NAKANO, Yasutane MORI, Reiko SEO, Taro TOGAMI, Tetsuya MASADA, Toshiaki KUSUHARA, Motoomi OHKAWA, Seigo NAGAO, Yuichi YAMASHITA, Satoshi SUGIURA

Author information

Takashi ISHIMORI
Department of Radiology, Faculty of Medicine, Kagawa University
Satoru NAKANO
Department of Radiology, Kurashiki Central Hospital
Yasutane MORI
Department of Radiology, Uchinomi Hospital
Reiko SEO
Department of Radiology, Faculty of Medicine, Kagawa University
Taro TOGAMI
Department of Radiology, Faculty of Medicine, Kagawa University
Tetsuya MASADA
Department of Neurosurgery, Faculty of Medicine, Kagawa University
Toshiaki KUSUHARA
Department of Radiology, Faculty of Medicine, Kagawa University
Motoomi OHKAWA
Department of Radiology, Faculty of Medicine, Kagawa University
Seigo NAGAO
Department of Neurosurgery, Faculty of Medicine, Kagawa University
Yuichi YAMASHITA
Toshiba Medical Systems Corporation
Satoshi SUGIURA
Toshiba Medical Systems Corporation

Keywords: deep brain stimulation, MRI, Parkinson's disease, subthalamic nucleus, three-dimensional phase sensitive IR

JOURNAL OPEN ACCESS

2007 Volume 6 Issue 4 Pages 225-229

DOI https://doi.org/10.2463/mrms.6.225

Details

Abstract

Purpose: We assessed the feasibility of utilizing three-dimensional (3D) phase sensitive inversion recovery (IR) images for preoperatively determining deep brain stimulator position.
Methods: We measured geometric distortion with a grid phantom and evaluated images of 3 volunteers to determine optimum imaging parameters for 3D phase sensitive IR.
Results: Geometric distortion measured less than 1.0%. Respective inversion and recovery times, which provided high T₁ contrast between the subthalamic nucleus and adjacent tissue, were 200 and 4000 ms. In studies of 3 volunteers and 2 patients, the subthalamic nucleus was clearly depicted in 3D phase sensitive IR images. The measured coordinates of the subthalamic nucleus agreed well with those calculated by conventional estimation from midpoint of the anterior and posterior commissure.
Conclusion: Three-dimensional phase sensitive inversion recovery was useful in visualizing the subthalamic nucleus for effective deep brain stimulation.

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