REVIEW  HIGH-GRADE GLIOMA 

The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2018 September;62(3):239-53

DOI: 10.23736/S1824-4785.18.03086-8

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma

Whitney B. POPE ✉, Garth BRANDAL

Department of Radiological Sciences, David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA, USA

Magnetic resonance imaging is integral to the care of patients with high-grade gliomas. Anatomic detail can be acquired with conventional structural imaging, but newer approaches also add capabilities to interrogate image-derived physiologic and molecular characteristics of central nervous system neoplasms. These advanced imaging techniques are increasingly employed to generate biomarkers that better reflect tumor burden and therapy response. The following is an overview of current strategies based on advanced magnetic resonance imaging that are used in the assessment of high-grade glioma patients with an emphasis on how novel imaging biomarkers can potentially advance patient care.

KEY WORDS: Glioma - Glioblastoma - Diffusion magnetic resonance imaging - Magnetic resonance angiography - Spectrum analysis