Effect of Implantation of Carbachol Pellet Near the Suprachiasmatic Nucleus on the Free-Running Period of Rat Locomotor Activity Rhythm
1987 Volume 37 Issue 2 Pages 321-326
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1987 Volume 37 Issue 2 Pages 321-326
To clarify the effect of a cholinergic agent on free-running period of circadian rhythm, locomotor activities were continuously recorded in the rat implanted with a paraffin pellet mixed with or without carbachol near the suprachiasmatic nucleus. Implantation of carbachol, but not paraffin alone, resulted in shortening of the free-running period under constant darkness.
