Primary Pancreatic Malignant Lymphoma Diagnosed from Endoscopic Ultrasound-guided Fine-needle Aspiration Findings

Nobuhiko Fukuba; Ichiro Moriyama; Shunji Ishihara; Hiroki Sonoyama; Noritsugu Yamashita; Yasumasa Tada; Akihiko Oka; Naoki Oshima; Takafumi Yuki; Kousaku Kawashima; Yoshikazu Kinoshita

doi:10.2169/internalmedicine.55.5749

CASE REPORTS

Primary Pancreatic Malignant Lymphoma Diagnosed from Endoscopic Ultrasound-guided Fine-needle Aspiration Findings

Nobuhiko Fukuba, Ichiro Moriyama, Shunji Ishihara, Hiroki Sonoyama, Noritsugu Yamashita, Yasumasa Tada, Akihiko Oka, Naoki Oshima, Takafumi Yuki, Kousaku Kawashima, Yoshikazu Kinoshita

Author information

Nobuhiko Fukuba
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Ichiro Moriyama
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Division of Cancer Center, Shimane University Hospital, Japan
Shunji Ishihara
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Hiroki Sonoyama
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Noritsugu Yamashita
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Yasumasa Tada
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Akihiko Oka
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Naoki Oshima
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Takafumi Yuki
Division of Gastrointestinal Endoscopy, Shimane University Hospital, Japan
Kousaku Kawashima
Department of Internal Medicine II, Shimane University School of Medicine, Japan
Yoshikazu Kinoshita
Department of Internal Medicine II, Shimane University School of Medicine, Japan

Keywords: EUS-FNA, diffuse large B cell lymphoma, pancreas

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 1 Pages 31-35

DOI https://doi.org/10.2169/internalmedicine.55.5749

Details

Abstract

A 60-year-old woman was admitted to our hospital with upper abdominal pain and jaundice. Computed tomography showed a 9-cm mass that was penetrated by the common hepatic artery in the pancreatic head area. Endoscopic retrograde pancreatography revealed no stenosis or obstruction of the main pancreatic duct, and a cytologic examination of the patient's pancreatic juice was negative. Next, endoscopic ultrasound-guided fine needle aspiration was performed. The immunohistological findings of the specimen revealed a diffuse large B-cell lymphoma. The size of the tumor was significantly reduced after 8 cycles of R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone).

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