Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Late-onset Anticonvulsant Hypersensitivity Syndrome Mimicking Lymphoma
Ayfer GedukElif Birtas AtesogluOzgur MehtapEsra Terzi DemirsoyBurak CanPinar TarkunAbdullah Hacihanefioglu
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JOURNAL OPEN ACCESS

2015 Volume 54 Issue 24 Pages 3201-3204

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Abstract

Anticonvulsant hypersensitivity syndrome is a fatal, idiosyncratic drug reaction that is caused by aromatic antiepileptic drugs. This cutaneous drug reaction is also called pseudolymphoma because of its clinical and histological similarities with malignant lymphoma. The primary clinical findings are fever, skin rashes, enlarged lymph nodes, single or multiple internal organ involvement and hematological abnormalities. Typically, anticonvulsant hypersensitivity syndrome occurs 1-8 weeks after drug administration. We herein present the case of a patient who had been on anticonvulsant therapy for five years and died from late-onset anticonvulsant hypersensitivity syndrome.

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© 2015 by The Japanese Society of Internal Medicine
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