2010 Volume 22 Issue 4 Pages 239-243
Low-grade myofibroblastic sarcoma (LGMS) represents a distinct atypical myofibroblastic tumor that occurs at several sites, primarily within the head and neck regions. A painless, enlarged mass is the most common clinical presentation, but a definitive diagnosis requires both histopathological and immunohistochemical analyses. Histologically, LGMS commonly presents as a cellular lesion composed of spindle-shaped tumor cells arranged primarily in fascicles with a diffusely infiltrative pattern. Immunohistochemically, LGMS shows positive staining for at least one myogenic marker, such as desmin or muscle actin. Here we report a case of LGMS in the base of the tongue. Our case showed positive immunostaining for desmin and vimentin, and was thus diagnosed as LGMS. The patient received surgery, but no chemotherapy or radiotherapy, and was completely without evidence of the disease 38 months after the surgery.
