12 June 2018 : Clinical Research
Mediating Effects of Patients’ Stigma and Self-Efficacy on Relationships Between Doctors’ Empathy Abilities and Patients’ Cellular Immunity in Male Breast Cancer Patients
Ningxi Yang12ABEF, Yingnan Cao3BCDE, Xiaoyan Li1BCD, Shiyue Li1AEG*, Hong Yan1BEG, Qingshan Geng4AEFDOI: 10.12659/MSM.910794
Med Sci Monit 2018; 24: CLR3978-3986
Abstract
BACKGROUND: Doctors’ empathy is closely related to patients’ health. This study aimed to examine whether patients’ stigma and self-efficacy play a mediating role in the relationship between doctors’ empathy abilities and patients’ cellular immunity in male patients with breast cancer.
MATERIAL AND METHODS: Doctors’ empathy scores and patients’ demographic data, disease condition, stigma, and self-efficacy were measured. Patient T cell subset was tested at admission and 3 months after the operation and was compared by paired t test. The multivariate linear regression model was applied to analyze the factors influencing the immune index. Pearson correlation analysis and structural equation modeling were applied to explore the relationships among patients’ stigma, self-efficacy, and cellular immunity and doctors’ empathy abilities.
RESULTS: At the 2 time points, only the change in NK subset was statistically significant, while the changes in percentage of CD3+, CD4+, CD8+, and B cells were not statistically significant. The doctors’ empathy abilities were negatively correlated with patients’ stigma and were positively related to patients’ self-efficacy. Patients’ stigma was negatively related to NK subset, while self-efficacy was positively associated with NK subset. Patients’ stigma and self-efficacy played a mediating role in the relationship between doctors’ empathy abilities and patients’ NK subset, and stigma had a stronger effect than self-efficacy.
CONCLUSIONS: Doctors’ empathy abilities affected breast cancer patients’ NK subset through their stigma and self-efficacy. The mental health of male breast cancer patients need more attention and empathy education needs to be improved.
Keywords: Breast Neoplasms, Male, Empathy, Immunity, Cellular, Self Efficacy
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
Clinical Research
Effectiveness of Shoulder Taping in Treating Hemiplegic Shoulder Subluxation: A Randomized Controlled Study...Med Sci Monit In Press; DOI: 10.12659/MSM.944222
Clinical Research
Comparison of Fentanyl, Ketamine, and Lidocaine Combined with Propofol Anesthesia in Patients with Crohn Di...Med Sci Monit In Press; DOI: 10.12659/MSM.944116
Database Analysis
ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular CarcinomaMed Sci Monit In Press; DOI: 10.12659/MSM.943523
Laboratory Research
Effect of Dentin Contamination with Hemostatic Agents and Cleaning Techniques on Bonding with Self-Adhesive...Med Sci Monit In Press; DOI: 10.12659/MSM.943353
Most Viewed Current Articles
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952